Copper-Catalyzed Asymmetric Deconstructive Alkynylation of Cyclic Oximes

Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

(2020) Zhaodong Li et al.   Nature Communications

When Light Meets Nitrogen-Centered Radicals: From Reagents to Catalysts

(2020) Xiao-Ye Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Visible Light-Driven Radical-Mediated C–C Bond Cleavage/Functionalization in Organic Synthesis

(2020) Xiao-Ye Yu et al.   CHEMICAL REVIEWS

Copper-Catalyzed Asymmetric Radical 1,2-Carboalkynylation of Alkenes with Alkyl Halides and Terminal Alkynes

(2020) Xiao-Yang Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light-Driven Copper-Catalyzed C(sp3)–O Cross-Coupling of Benzylic Radicals with Phenols

(2020) Xiao-Ye Yu et al.   ORGANIC LETTERS

Electrochemical Annulation–Iodosulfonylation of 1,5-Enyne-containing para-Quinone Methides (p-QMs) to Access (E)-Spiroindenes

(2020) Hang-Dong Zuo et al.   ORGANIC LETTERS

Cobalt/Bisoxazolinephosphine-Catalyzed Asymmetric Alkynylation of Isatins

(2020) Jia-Feng Chen et al.   ORGANIC LETTERS

Photoinduced Copper‐Catalyzed Asymmetric Decarboxylative Alkynylation with Terminal Alkynes

(2020) Hai-Dong Xia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances for the photoinduced C C bond cleavage of cycloketone oximes

(2020) Wei Xiao et al.   CHINESE CHEMICAL LETTERS

Enantioselective Copper-Catalyzed Alkynylation of Benzylic C–H Bonds via Radical Relay

(2020) Liang Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper‐Catalyzed Enantioconvergent Cross‐Coupling of Racemic Alkyl Bromides with Azole C(sp2)–H Bonds

(2020) Xiao-Long Su et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper‐Catalyzed Asymmetric Coupling of Allenyl Radicals with Terminal Alkynes to Access Tetrasubstituted Allenes

(2020) Xiao-Yang Dong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cleavage of Carbon–Carbon σ-Bonds of Four-Membered Rings

(2020) Masahiro Murakami et al.   CHEMICAL REVIEWS

Organocatalytic Enantioselective Conjugate Alkynylation of β-Aminoenones: Access to Chiral β-Alkynyl-β-Amino Carbonyl Derivatives

(2020) Jian-Fei Wang et al.   ORGANIC LETTERS

Photo-mediated selective deconstructive geminal dihalogenation of trisubstituted alkenes

(2020) Han Wang et al.   Nature Communications

Ring-opening functionalizations of unstrained cyclic amines enabled by difluorocarbene transfer

(2020) Youyoung Kim et al.   Nature Communications

Recent Developments in Radical Cross‐Coupling of Redox‐Active Cycloketone Oximes

(2020) Fang Xiao et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Intermolecular Aminoalkynylation of Styrenes via Copper-Catalyzed Radical Relay

(2020) Zhoumi Hu et al.   ORGANIC LETTERS

Deacylative transformations of ketones via aromatization-promoted C–C bond activation

(2019) Yan Xu et al.   NATURE

Transition-Metal-Free Deconstructive Lactamization of Piperidines

(2019) Julio Romero-Ibañez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Acyclic Quaternary Carbon Stereocenters by Catalytic Asymmetric Hydroalkynylation of Unactivated Alkenes

(2019) Zi-Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Dual-Functional Chiral Cu-Catalyst-Induced Photoredox Asymmetric Cyanofluoroalkylation of Alkenes

(2019) Quanping Guo et al.   ACS Catalysis

Radical-Promoted C−C Bond Cleavage: A Deconstructive Approach for Selective Functionalization

(2019) Sara P. Morcillo   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cu/chiral phosphoric acid-catalyzed radical-initiated asymmetric aminosilylation of alkene with hydrosilane

(2019) Yang Zeng et al.   Science China-Chemistry

Photoinduced Copper-Catalyzed Radical Aminocarbonylation of Cycloketone Oxime Esters

(2019) Bin Lu et al.   ACS Catalysis

Copper(I)-Catalyzed Asymmetric Reactions Involving Radicals

(2019) Qiang-Shuai Gu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Applications of fluorine-containing amino acids for drug design

(2019) Haibo Mei et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A general asymmetric copper-catalysed Sonogashira C(sp3)–C(sp) coupling

(2019) Xiao-Yang Dong et al.   Nature Chemistry

Photocatalytic Annulation–Alkynyl Migration Strategy for Multiple Functionalization of Dual Unactivated Alkenes

(2019) Qi Zhao et al.   ORGANIC LETTERS

Enantioselective Radical Ring-Opening Cyanation of Oxime Esters by Dual Photoredox and Copper Catalysis

(2019) Jun Chen et al.   ORGANIC LETTERS

Enantioselective cyanation via radical-mediated C–C single bond cleavage for synthesis of chiral dinitriles

(2019) Tao Wang et al.   Nature Communications

Enantioselective Alkynylation of Trifluoromethyl Ketones Catalyzed by Cation-Binding Salen Nickel Complexes

(2019) Dongseong Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed enantioselective Sonogashira-type oxidative cross-coupling of unactivated C(sp3)−H bonds with alkynes

(2019) Zhen-Hua Zhang et al.   Nature Communications

(Guanidine)copper Complex-Catalyzed Enantioselective Dynamic Kinetic Allylic Alkynylation under Biphasic Condition

(2018) Xi-Yang Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Merging “Anti-Baldwin” 3-Exo-Dig Cyclization with 1,2-Alkynyl Migration for Radical Alkylalkynylation of Unactivated Olefins

(2018) Qi Zhao et al.   ORGANIC LETTERS

Fine-tuned organic photoredox catalysts for fragmentation-alkynylation cascades of cyclic oxime ethers

(2018) Franck Le Vaillant et al.   Chemical Science

Enantioselective Trifluoromethylalkynylation of Alkenes via Copper-Catalyzed Radical Relay

(2018) Liang Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deconstructive fluorination of cyclic amines by carbon-carbon cleavage

(2018) Jose B. Roque et al.   SCIENCE

Copper-Catalyzed Radical Cross-Coupling of Redox-Active Oxime Esters, Styrenes, and Boronic Acids

(2018) Xiao-Ye Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deconstructive diversification of cyclic amines

(2018) Jose B. Roque et al.   NATURE

Highly Enantioselective Synthesis of Propargyl Amides through Rh-Catalyzed Asymmetric Hydroalkynylation of Enamides: Scope, Mechanism, and Origin of Selectivity

(2017) Xiao-Yan Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Enantioselective Hydroalkynylation of Enamides for the Synthesis of Homopropargyl Amides

(2016) Xiao-Yan Bai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper/Guanidine-Catalyzed Asymmetric Alkynylation of Isatins

(2016) Quangang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alkenylation of Arenes and Heteroarenes with Alkynes

(2016) Vadim P. Boyarskiy et al.   CHEMICAL REVIEWS

Synthesis of Amides with Remote Stereocenters by Catalytic Asymmetric γ-Alkynylation of α,β-Unsaturated Amides

(2016) Zi-Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Unsaturated N-Heterocycles by Cycloadditions of Aziridines and Alkynes

(2016) Jian-Jun Feng et al.   ACS Catalysis

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Dual 1,1-H-Abstraction/Insertion for Domino Spirocyclizations

(2015) Jiang-Kai Qiu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Enantioselective Allylic Alkylation of Terminal Alkyne Pronucleophiles

(2014) Ayumi Harada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alkynes in Organocatalysis

(2014) Riccardo Salvio et al.   Asian Journal of Organic Chemistry

Iridium-Catalyzed Enantioselective Allylic Alkynylation

(2013) James Y. Hamilton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Reactions of Acetylene: A Feedstock for the Chemical Industry Revisited

(2013) Ioan-Teodor Trotuş et al.   CHEMICAL REVIEWS

Production of Acetylene and Acetylene-based Chemicals from Coal

(2013) Harold Schobert   CHEMICAL REVIEWS

Regiocontrolled Hydroarylation of (Trifluoromethyl)acetylenes in Superacids: Synthesis of CF3-Substituted 1,1-Diarylethenes

(2013) Haider M. H. Alkhafaji et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Synthesis of Alkyne-Substituted Quaternary Carbon Stereogenic Centers through NHC−Cu-Catalyzed Allylic Substitution Reactions with (i-Bu)2(Alkynyl)aluminum Reagents

(2011) Jennifer A. Dabrowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS