A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantation

COVID‐19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine

(2020) Francesco Fontana et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Pig-to-non-human primate heart transplantation: the final step toward clinical xenotransplantation?

(2020) Bruno Reichart et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Interleukin 6

(2020) Stanley C. Jordan et al.   TRANSPLANTATION

Early Hemoperfusion for Cytokine Removal May Contribute to Prevention of Intubation in Patients Infected with COVID-19

(2020) Ali Esmaeili Vardanjani et al.   BLOOD PURIFICATION

Effect of Intraoperative Dexamethasone on Major Complications and Mortality Among Infants Undergoing Cardiac Surgery

(2020) Vladimir Lomivorotov et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

(2020) Bingwen Liu et al.   JOURNAL OF AUTOIMMUNITY

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Long-Term Survival of Pig-to-Rhesus Macaque Renal Xenografts is Dependent on CD4 T cell Depletion

(2019) S C Kim et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Evidence for the important role of inflammation in xenotransplantation

(2019) Juan Li et al.   Journal of Inflammation-London

Capillary leak syndrome: a cytokine and catecholamine storm?

(2019) Eric Siddall et al.   KIDNEY INTERNATIONAL

Early experience with preclinical peri-operative cardiac xenograft dysfunction in a single program

(2019) Laura DiChiacchio et al.   ANNALS OF THORACIC SURGERY

Improved outcomes of islet autotransplant after total pancreatectomy by combined blockade of IL-1β and TNFα

(2018) B. Naziruddin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates

(2018) Liaoran Wang et al.   TRANSPLANTATION

Regulation of the Immune Response by the Inflammatory Metabolic Microenvironment in the Context of Allotransplantation

(2018) Nicolas Degauque et al.   Frontiers in Immunology

Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft Survival

(2018) Andrew B. Adams et al.   ANNALS OF SURGERY

Zero-Balance Ultrafiltration of Priming Blood Attenuates Procalcitonin and Improves the Respiratory Function in Infants After Cardiopulmonary Bypass: A Randomized Controlled Trial

(2018) Maziar Gholampour Dehaki et al.   ARTIFICIAL ORGANS

Consistent success in life-supporting porcine cardiac xenotransplantation

(2018) Matthias Längin et al.   NATURE

Adrenaline fuels a cytokine storm during immunotherapy

(2018) Stanley R. RIddell   NATURE

The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome?

(2018) David Cleveland et al.   PEDIATRIC CARDIOLOGY

Serum amyloid a as an indicator of impending xenograft failure: Experimental studies

(2018) Guoqiang Zhang et al.   International Journal of Surgery

An Investigation of Extracellular Histones in Pig-To-Baboon Organ Xenotransplantation

(2017) Tao Li et al.   TRANSPLANTATION

Human IL-6, IL-17, IL-1β, and TNF-α differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial cells

(2017) Hanchao Gao et al.   XENOTRANSPLANTATION

Therapeutic regulation of systemic inflammation in xenograft recipients

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

Peri- and Postoperative Treatment with the Interleukin-1 Receptor Antagonist Anakinra Is Safe in Patients Undergoing Renal Transplantation: Case Series and Review of the Literature

(2017) Catharina M. Mulders-Manders et al.   Frontiers in Pharmacology

Erosion of Transplantation Tolerance After Infection

(2016) J. S. Young et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Systemic inflammatory response syndrome is reduced by preoperative plasma-thrombo-leukocyte aphaeresis in a pig model of cardiopulmonary bypass

(2016) Robert Wagner et al.   BIOMEDICAL PAPERS-OLOMOUC

Activation of the lectin pathway of complement by cardiopulmonary bypass contributes to the development of systemic inflammatory response syndrome after paediatric cardiac surgery

(2016) I. Pągowska-Klimek et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome

(2016) Bita Shakoory et al.   CRITICAL CARE MEDICINE

Effect of Ultrafiltration on Pulmonary Function and Interleukins in Patients Undergoing Cardiopulmonary Bypass

(2016) Carolina Kosour et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Role of TLRs and DAMPs in allograft inflammation and transplant outcomes

(2016) Faouzi Braza et al.   Nature Reviews Nephrology

Retrospective analysis of eliminating modified ultrafiltration after pediatric cardiopulmonary bypass

(2016) Craig M. McRobb et al.   PERFUSION-UK

Thyroid hormone: relevance to xenotransplantation

(2016) Hayato Iwase et al.   XENOTRANSPLANTATION

The pathobiology of pig-to-primate xenotransplantation: a historical review

(2016) David K.C. Cooper et al.   XENOTRANSPLANTATION

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

(2016) Muhammad M. Mohiuddin et al.   Nature Communications

Circulating histones for predicting prognosis after cardiac surgery: a prospective study

(2016) Hongxiang Gao et al.   Interactive Cardiovascular and Thoracic Surgery

Effect of Timing and Route of Methylprednisolone Administration During Pediatric Cardiac Surgical Procedures

(2015) Juho Keski-Nisula et al.   ANNALS OF THORACIC SURGERY

A Single-Center Randomized Trial of Intraoperative Zero-Balanced Ultrafiltration During Cardiopulmonary Bypass for Patients With Impaired Kidney Function Undergoing Cardiac Surgery

(2015) Bashir M. Matata et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Further evidence for sustained systemic inflammation in xenograft recipients (SIXR)

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Systemic inflammation in xenograft recipients (SIXR): A new paradigm in pig-to-primate xenotransplantation?

(2015) Mohamed B. Ezzelarab et al.   International Journal of Surgery

Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation

(2014) Muhammad M. Mohiuddin et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Thyroid Hormone Therapy in the Management of 63,593 Brain-Dead Organ Donors

(2014) Dimitri Novitzky et al.   TRANSPLANTATION

Systemic inflammation in xenograft recipients precedes activation of coagulation

(2014) Mohamed B. Ezzelarab et al.   XENOTRANSPLANTATION

Plasma free triiodothyronine (fT3) levels in baboons undergoing pig organ transplantation: relevance to early recovery of organ function

(2014) Hayato Iwase et al.   XENOTRANSPLANTATION

One-Year Heterotopic Cardiac Xenograft Survival in a Pig to Baboon Model

(2013) M. M. Mohiuddin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Anakinra and Tocilizumab Enhance Survival and Function of Human Islets during Culture: Implications for Clinical Islet Transplantation

(2013) Afaf Sahraoui et al.   CELL TRANSPLANTATION

Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model

(2013) Muhammad M. Mohiuddin et al.   XENOTRANSPLANTATION

Cardiac xenotransplantation

(2012) Guerard W. Byrne et al.   Current Opinion in Organ Transplantation

Triiodothyronine supplementation and cytokines during cardiopulmonary bypass in infants and children

(2012) James R. Priest et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Serum C-reactive protein is a useful biomarker for predicting outcomes after liver transplantation in patients with hepatocellular carcinoma

(2012) Ho Jung An et al.   LIVER TRANSPLANTATION

Anakinra Potentiates the Protective Effects of Etanercept in Transplantation of Marginal Mass Human Islets in Immunodeficient Mice

(2011) M. McCall et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Innate immunity in transplant tolerance and rejection

(2011) Shaun P. Murphy et al.   IMMUNOLOGICAL REVIEWS

Changes in cardiac gene expression after pig-to-primate orthotopic xenotransplantation

(2011) Guerard W. Byrne et al.   XENOTRANSPLANTATION

The Relationship Between Inflammatory Activation and Clinical Outcome After Infant Cardiopulmonary Bypass

(2010) Catherine K. Allan et al.   ANESTHESIA AND ANALGESIA

Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): A Multicenter Placebo-Controlled Randomized Trial: Age Analysis

(2010) M. A. Portman et al.   CIRCULATION

Protective Effects of Steroids in Cardiac Surgery: A Meta-Analysis of Randomized Double-Blind Trials

(2010) Giangiuseppe Cappabianca et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Modified ultrafiltration attenuates pulmonary-derived inflammatory mediators in response to cardiopulmonary bypass☆,☆☆

(2010) Broadus Zane Atkins et al.   Interactive Cardiovascular and Thoracic Surgery

A review of studies relating to thyroid hormone therapy in brain-dead organ donors

(2009) Davi et al.   Frontiers in Bioscience-Landmark

IL-6 and TNF-  Synergistically Inhibit Allograft Acceptance

(2009) H. Shen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Clinical benefit of steroid use in patients undergoing cardiopulmonary bypass: a meta-analysis of randomized trials

(2008) R. P. Whitlock et al.   EUROPEAN HEART JOURNAL

Effect of exogenous catecholamines on tumor necrosis factor alpha, interleukin-6, interleukin-10 and beta-endorphin levels following severe trauma

(2008) Chrysanthi Batistaki et al.   VASCULAR PHARMACOLOGY