Extracellular vesicle-mediated miR135a-5p transfer in hypertensive rat contributes to vascular smooth muscle cell proliferation via targeting FNDC5

FNDC5 Attenuates Oxidative Stress and NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells via Activating the AMPK-SIRT1 Signal Pathway

(2020) Bing Zhou et al.   Oxidative Medicine and Cellular Longevity

New insights into the cellular activities of Fndc5/Irisin and its signaling pathways

(2020) Farzaneh Rabiee et al.   Cell and Bioscience

miRNA Reference Genes in Extracellular Vesicles Released from Amniotic Membrane-Derived Mesenchymal Stromal Cells

(2020) Enrico Ragni et al.   Pharmaceutics

MiRNAs, lncRNAs, and circular RNAs as mediators in hypertension-related vascular smooth muscle cell dysfunction

(2020) Ji-Ru Zhang et al.   HYPERTENSION RESEARCH

Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective Effectors

(2020) Saveria Femminò et al.   VASCULAR PHARMACOLOGY

Exosomal miR-211 contributes to pulmonary hypertension via attenuating CaMK1/PPAR-γaxis

(2020) Shuhao Zhang et al.   VASCULAR PHARMACOLOGY

Downregulation of lysyl oxidase‐like 4 LOXL4 by miR‐135a‐5p promotes lung cancer progression in vitro and in vivo

(2019) Ying Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition

(2019) Kai-li Zhang et al.   ACTA PHARMACOLOGICA SINICA

FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NFκB-mediated NLRP3 upregulation

(2019) Ying-Hao Zang et al.   VASCULAR PHARMACOLOGY

Recent Developments in Vascular Adventitial Pathobiology

(2019) Maria G. Tinajero et al.   AMERICAN JOURNAL OF PATHOLOGY

MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression

(2019) Xing-Sheng Ren et al.   Journal of Extracellular Vesicles

Inhibiting extracellular vesicles formation and release: a review of EV inhibitors

(2019) Mariadelva Catalano et al.   Journal of Extracellular Vesicles

Vascular smooth muscle cell proliferation as a therapeutic target. Part 1: molecular targets and pathways

(2018) Dongdong Wang et al.   BIOTECHNOLOGY ADVANCES

MiR-135a-5p represses proliferation of HNSCC by targeting HOXA10

(2018) Lei-ming Guo et al.   CANCER BIOLOGY & THERAPY

Fibronectin type III domain containing 5 attenuates NLRP3 inflammasome activation and phenotypic transformation of adventitial fibroblasts in spontaneously hypertensive rats

(2018) Li Ling et al.   JOURNAL OF HYPERTENSION

FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity

(2018) Xiao-Qing Xiong et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Dysregulation of miR-135a-5p promotes the development of rat pulmonary arterial hypertension in vivo and in vitro

(2018) Hong-mei Liu et al.   ACTA PHARMACOLOGICA SINICA

Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration

(2018) Ying Tong et al.   HYPERTENSION

Role of flow-sensitive microRNAs and long noncoding RNAs in vascular dysfunction and atherosclerosis

(2018) Sandeep Kumar et al.   VASCULAR PHARMACOLOGY

The function of miR-143, miR-145 and the MiR-143 host gene in cardiovascular development and disease

(2018) Francesca Vacante et al.   VASCULAR PHARMACOLOGY

Endothelial Cells Inhibit the Angiotensin II Induced Phenotypic Modulation of Rat Vascular Adventitial Fibroblasts

(2017) Jia-Ying Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension

(2017) Hai-Jian Sun et al.   Cell Death & Disease

Salusin-β Promotes Vascular Smooth Muscle Cell Migration and Intimal Hyperplasia After Vascular Injury via ROS/NFκB/MMP-9 Pathway

(2016) Hai-Jian Sun et al.   ANTIOXIDANTS & REDOX SIGNALING

FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation, and Lipogenesis in Mice

(2016) Tong-Yan Liu et al.   DIABETES

FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity

(2015) Xiao-Qing Xiong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes

(2015) T.-Y. Liu et al.   CLINICAL SCIENCE

The Adventitia: Essential Regulator of Vascular Wall Structure and Function

(2012) Kurt R. Stenmark et al.   Annual Review of Physiology

From Skeleton to Cytoskeleton

(2012) Chi Yung Yuen et al.   CIRCULATION RESEARCH

Vascular Remodeling in Hypertension

(2011) Ernesto L. Schiffrin   HYPERTENSION