Journal
BIOTECHNOLOGY ADVANCES
Volume 36, Issue 6, Pages 1586-1607Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2018.04.006
Keywords
Atherosclerosis; Cardiovascular diseases; Cell cycle; Proliferation; Pulmonary hypertension; Restenosis; Signaling pathway; Vascular smooth muscle cells
Categories
Funding
- Homing Grant from Foundation for Polish Sciences [DPK/432-935/18]
- Austrian Science Fund (FWF) project [P25971-B23]
- Ernst Mach Grant-worldwide [ICM-2016-03293]
- Post-doc from KNOW - Healthy Animals - Safe Food [KNOW2017/CB/PDC4/6]
- Polish KNOW (Leading National Research Centre) Scientific Consortium Healthy Animal Safe Food [05-1/KNOW2/2015]
- Peter and Traudl Engelhorn Foundation for the promotion of Life Sciences
Ask authors/readers for more resources
Cardiovascular diseases are a major cause of human death worldwide. Excessive proliferation of vascular smooth muscle cells contributes to the etiology of such diseases, including atherosclerosis, restenosis, and pulmonary hypertension. The control of vascular cell proliferation is complex and encompasses interactions of many regulatory molecules and signaling pathways. Herein, we recapitulated the importance of signaling cascades relevant for the regulation of vascular cell proliferation. Detailed understanding of the mechanism underlying this process is essential for the identification of new lead compounds (e.g., natural products) for vascular therapies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available