Leptin Regulation of Synaptic Function at Hippocampal TA-CA1 and SC-CA1 Synapses: Implications for Health and Disease

Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses

(2017) Gemma McGregor et al.   FASEB JOURNAL

Amyloid-β Decreases Cell-Surface AMPA Receptors by Increasing Intracellular Calcium and Phosphorylation of GluR2

(2017) Shi-Jie Liu et al.   JOURNAL OF ALZHEIMERS DISEASE

Leptin Reduces Pathology and Improves Memory in a Transgenic Mouse Model of Alzheimer's Disease

(2017) Steven J. Greco et al.   JOURNAL OF ALZHEIMERS DISEASE

A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

(2016) Yasaman Malekizadeh et al.   CEREBRAL CORTEX

IRS proteins and diabetic complications

(2016) Deborah P. Lavin et al.   DIABETOLOGIA

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy

(2016) C. A. Booth et al.   JOURNAL OF NEUROSCIENCE

Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease

(2016) T.L. Platt et al.   NEUROSCIENCE

Leptin Regulation of Immune Responses

(2016) Caitlin Naylor et al.   TRENDS IN MOLECULAR MEDICINE

Long-term Potentiation at Temporoammonic Path-CA1 Synapses in Freely Moving Rats

(2016) Jossina Gonzalez et al.   Frontiers in Neural Circuits

Complementary Roles of Human Hippocampal Subfields in Differentiation and Integration of Spatial Context

(2015) Jared Stokes et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment

(2015) Sasanka Chakrabarti et al.   Aging and Disease

Leptin-Induced Spine Formation Requires TrpC Channels and the CaM Kinase Cascade in the Hippocampus

(2014) M. Dhar et al.   JOURNAL OF NEUROSCIENCE

Adipokine pathways are altered in hippocampus of an experimental mouse model of Alzheimer’s disease

(2014) I. Pedrós et al.   Journal of Nutrition Health & Aging

Leptin Induces Hippocampal Synaptogenesis via CREB-Regulated MicroRNA-132 Suppression of p250GAP

(2014) Matasha Dhar et al.   MOLECULAR ENDOCRINOLOGY

Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy

(2014) Hervé Maurin et al.   PLoS One

Leptin at the Intersection of Neuroendocrinology and Metabolism: Current Evidence and Therapeutic Perspectives

(2013) Maria Dalamaga et al.   Cell Metabolism

The interplay between Hebbian and homeostatic synaptic plasticity

(2013) Nathalia Vitureira et al.   JOURNAL OF CELL BIOLOGY

Spatial memory impairment and changes in hippocampal morphology are triggered by high-fat diets in adolescent mice. Is there a role of leptin?

(2013) Ismael Valladolid-Acebes et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Leptin regulation of hippocampal synaptic function in health and disease

(2013) A. J. Irving et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β

(2012) Gayle H. Doherty et al.   NEUROBIOLOGY OF AGING

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

(2012) Céline S. Nicolas et al.   NEURON

Diversity in NMDA Receptor Composition

(2012) Antonio Sanz-Clemente et al.   NEUROSCIENTIST

NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity

(2011) Peter R. Moult et al.   NEUROPHARMACOLOGY

Adipocytokines and CD34+ Progenitor Cells in Alzheimer's Disease

(2011) Boris Bigalke et al.   PLoS One

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

(2010) P. R. Moult et al.   JOURNAL OF NEUROSCIENCE

Long-term depression in the CNS

(2010) Graham L. Collingridge et al.   NATURE REVIEWS NEUROSCIENCE

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo

(2010) Michael A. Yassa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of glutamate receptor trafficking by leptin

(2009) Peter R. Moult et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Association of Plasma Leptin Levels With Incident Alzheimer Disease and MRI Measures of Brain Aging

(2009) Wolfgang Lieb   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Leptin targets in the mouse brain

(2009) Michael M. Scott et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Recruitment of N-Type Ca2+ Channels during LTP Enhances Low Release Efficacy of Hippocampal CA1 Perforant Path Synapses

(2009) Mohsin S. Ahmed et al.   NEURON

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Disruption of the direct perforant path input to the CA1 subregion of the dorsal hippocampus interferes with spatial working memory and novelty detection

(2008) David R. Vago et al.   BEHAVIOURAL BRAIN RESEARCH

Developmental changes in short-term facilitation are opposite at temporoammonic synapses compared to Schaffer collateral synapses onto CA1 pyramidal cells

(2008) Haley E. Speed et al.   HIPPOCAMPUS

Leptin reverses long-term potentiation at hippocampal CA1 synapses

(2008) Peter R. Moult et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons

(2008) T Chiba et al.   MOLECULAR PSYCHIATRY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Leptin Replacement Improves Cognitive Development

(2008) Gilberto J. Paz-Filho et al.   PLoS One

A Review of Glutamate Receptors I: Current Understanding of Their Biology

(2008) Colin G. Rousseaux   Journal of Toxicologic Pathology

Convergence of entorhinal and CA3 inputs onto pyramidal neurons and interneurons in hippocampal area CA1—An anatomical study in the rat

(2007) Riichi Kajiwara et al.   HIPPOCAMPUS