A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis
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Title
A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 118, Issue 13, Pages e2025102118
Publisher
Proceedings of the National Academy of Sciences
Online
2021-03-26
DOI
10.1073/pnas.2025102118
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Note: Only part of the references are listed.- Inflammatory profiles relate to survival in subtypes of amyotrophic lateral sclerosis
- (2020) Mads Nikolaj Olesen et al. Neurology-Neuroimmunology & Neuroinflammation
- Systematic comparison of single-cell and single-nucleus RNA-sequencing methods
- (2020) Jiarui Ding et al. NATURE BIOTECHNOLOGY
- Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target
- (2020) Lauren Mifflin et al. NATURE REVIEWS DRUG DISCOVERY
- Neuroinflammation During RNA Viral Infections
- (2019) Robyn S. Klein et al. Annual Review of Immunology
- Microglial MHC class II is dispensable for experimental autoimmune encephalomyelitis and cuprizone-induced demyelination
- (2018) Yochai Wolf et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression
- (2018) Kezhou Zhu et al. Cell Death & Disease
- TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
- (2018) Daichao Xu et al. CELL
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases
- (2018) Junying Yuan et al. NATURE REVIEWS NEUROSCIENCE
- Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
- (2018) Qingyun Li et al. NEURON
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Microglia emerge as central players in brain disease
- (2017) Michael W Salter et al. NATURE MEDICINE
- Single-cell mRNA quantification and differential analysis with Census
- (2017) Xiaojie Qiu et al. NATURE METHODS
- Reversed graph embedding resolves complex single-cell trajectories
- (2017) Xiaojie Qiu et al. NATURE METHODS
- RIPK1 mediates a disease-associated microglial response in Alzheimer’s disease
- (2017) Dimitry Ofengeim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo
- (2016) B Shutinoski et al. CELL DEATH AND DIFFERENTIATION
- Single-cell barcoding and sequencing using droplet microfluidics
- (2016) Rapolas Zilionis et al. Nature Protocols
- RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS
- (2016) Yasushi Ito et al. SCIENCE
- How neuroinflammation contributes to neurodegeneration
- (2016) R. M. Ransohoff SCIENCE
- Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells
- (2015) Allon M. Klein et al. CELL
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Spatial reconstruction of single-cell gene expression data
- (2015) Rahul Satija et al. NATURE BIOTECHNOLOGY
- Microglia: Dynamic Mediators of Synapse Development and Plasticity
- (2015) Yuwen Wu et al. TRENDS IN IMMUNOLOGY
- Activation of Necroptosis in Multiple Sclerosis
- (2015) Dimitry Ofengeim et al. Cell Reports
- Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo
- (2014) Apostolos Polykratis et al. JOURNAL OF IMMUNOLOGY
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- I B Is a Transcriptional Key Regulator of CCL2/MCP-1
- (2013) D. G. Hildebrand et al. JOURNAL OF IMMUNOLOGY
- Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death
- (2013) Dimitry Ofengeim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
- (2013) Isaac M. Chiu et al. Cell Reports
- Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
- (2012) A Degterev et al. CELL DEATH AND DIFFERENTIATION
- A novel role for RIP1 kinase in mediating TNFα production
- (2012) D E Christofferson et al. Cell Death & Disease
- The Role of Microglia in the Healthy Brain
- (2011) M.-E. Tremblay et al. JOURNAL OF NEUROSCIENCE
- Optineurin in neurodegenerative diseases
- (2011) Tenshi Osawa et al. NEUROPATHOLOGY
- Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway
- (2008) Junichi Hitomi et al. CELL
- TNF and sTNFR1/2 plasma levels in ALS patients
- (2008) Cristina Cereda et al. JOURNAL OF NEUROIMMUNOLOGY
- Identification of RIP1 kinase as a specific cellular target of necrostatins
- (2008) Alexei Degterev et al. Nature Chemical Biology
- The Immunological Genome Project: networks of gene expression in immune cells
- (2008) Tracy S P Heng et al. NATURE IMMUNOLOGY
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