Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2–expressing Treg cells

Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4+Foxp3+ induced Treg cells in vitro and in vivo periphery in autoimmune diseases

(2019) Sujuan Yang et al.   Cell Death & Disease

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

(2019) Garima Garg et al.   Cell Reports

Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

(2019) James B. Wing et al.   IMMUNITY

Cre-loxP Reporter Mouse Reveals Stochastic Activity of the Foxp3 Promoter

(2019) Peter D. Bittner-Eddy et al.   Frontiers in Immunology

Hidden Caveat of Inducible Cre Recombinase

(2019) Makoto Kurachi et al.   IMMUNITY

Conditional Gene-Targeting in Mice: Problems and Solutions

(2018) Burkhard Becher et al.   IMMUNITY

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity

(2018) Kamar-Sulu N. Atretkhany et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells

(2018) Chihiro Ogawa et al.   Cell Reports

Effector Regulatory T Cell Differentiation and Immune Homeostasis Depend on the Transcription Factor Myb

(2017) Sheila Dias et al.   IMMUNITY

Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity

(2017) David Zemmour et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of GVHD by regulatory T cells depends on TNF produced by T cells and TNFR2 expressed by regulatory T cells

(2016) M. Leclerc et al.   BLOOD

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion

(2016) Martin Chopra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Suppressive activity of human regulatory T cells is maintained in the presence of TNF

(2016) Bruno Zaragoza et al.   NATURE MEDICINE

Antigen- and Cytokine-Driven Accumulation of Regulatory T Cells in Visceral Adipose Tissue of Lean Mice

(2015) Dmitriy Kolodin et al.   Cell Metabolism

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

(2015) Ajithkumar Vasanthakumar et al.   NATURE IMMUNOLOGY

Promiscuous Foxp3-cre activity reveals a differential requirement for CD28 in Foxp3+ and Foxp3− T cells

(2014) Dean Franckaert et al.   IMMUNOLOGY AND CELL BIOLOGY

Role of Blimp-1 in programing Th effector cells into IL-10 producers

(2014) Christian Neumann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The alarmin IL-33 promotes regulatory T-cell function in the intestine

(2014) Chris Schiering et al.   NATURE

Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

(2014) Sarah K. Williams et al.   PLoS One

A clinical conundrum: the detrimental effect of TNF antagonists in multiple sclerosis

(2013) Calliope A Dendrou et al.   PHARMACOGENOMICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

T-cell trafficking in the central nervous system

(2012) Federica Sallusto et al.   IMMUNOLOGICAL REVIEWS

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE

(2011) Niki Tsakiri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease

(2010) Romeo Sporici et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathogenic T cells have a paradoxical protective effect in murine autoimmune diabetes by boosting Tregs

(2010) Yenkel Grinberg-Bleyer et al.   JOURNAL OF CLINICAL INVESTIGATION

Curing CNS autoimmune disease with myelin-reactive Foxp3+Treg

(2009) Leigh A. Stephens et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets

(2009) Markus Feuerer et al.   IMMUNITY

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology