Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+Aβ1-42 peptide

Healthy Effects of Plant Polyphenols: Molecular Mechanisms

(2020) Manuela Leri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effect of rutin against colistin-induced oxidative stress, inflammation and apoptosis in rat brain associated with the CREB/BDNF expressions

(2020) Hamit Çelik et al.   MOLECULAR BIOLOGY REPORTS

Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage

(2020) Xin Tan et al.   Frontiers in Pharmacology

An Updated Review of Randomized Clinical Trials Testing the Improvement of Cognitive Function of Ginkgo biloba Extract in Healthy People and Alzheimer’s Patients

(2020) Haolong Liu et al.   Frontiers in Pharmacology

Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson’s Disease: A Comparative Study

(2020) Lyubka P. Tancheva et al.   Antioxidants

Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory Diseases

(2020) María Luisa Castejón et al.   Antioxidants

The effect of three polyphenols and some other anti-oxidant substances on amyloid fibril formation by human cystatin C

(2020) Alma Jahić et al.   NEUROCHEMISTRY INTERNATIONAL

Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+Aβ1-42 peptide in rat hippocampal neurons

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Correlations between Alzheimer`s disease and type 2 diabetes: focus on.

(2019) Vincenzo Fiore et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

The secreted APP ectodomain sAPPα, but not sAPPβ, protects neurons against Aβ oligomer-induced dendritic spine loss and increased tau phosphorylation

(2019) Christian Tackenberg et al.   Molecular Brain

Insulin Resistance and Oxidative Stress in the Brain: What’s New?

(2019) Mateusz Maciejczyk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Progression to type 2 diabetes mellitus and associated risk factors after hyperglycemia first detected in pregnancy: A cross-sectional study in Cape Town, South Africa

(2019) Tawanda Chivese et al.   PLOS MEDICINE

High glucose forces a positive feedback loop connecting ErbB4 expression and mTOR/S6K pathway to aggravate the formation of tau hyperphosphorylation in differentiated SH-SY5Y cells

(2018) Sheng-Dan Nie et al.   NEUROBIOLOGY OF AGING

TGF-β1 protection against Aβ1–42-induced hippocampal neuronal inflammation and apoptosis by TβR-I

(2018) Xiao-Xia Fang et al.   NEUROREPORT

Characteristic Metabolic Alterations Identified in Primary Neurons Under High Glucose Exposure

(2018) Liangcai Zhao et al.   Frontiers in Cellular Neuroscience

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Changes of S-allylmercaptocysteine and γ-glutamyl-S-allylmercaptocysteine contents and their putative production mechanisms in garlic extract during the aging process

(2018) Takuto Fujii et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective

(2017) Salvatore Bongarzone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metformin – a Future Therapy for Neurodegenerative Diseases

(2017) Magdalena Markowicz-Piasecka et al.   PHARMACEUTICAL RESEARCH

Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

(2017) Christine Xue et al.   Royal Society Open Science

Inhibition effect of cypermethrin mediated by co-regulators SRC-1 and SMRT in interleukin-6-induced androgen receptor activation

(2016) Qi Wang et al.   CHEMOSPHERE

Hyperglycemia Increases the Production of Amyloid Beta-Peptide Leading to Decreased Endothelial Tight Junction

(2016) A-Ching Chao et al.   CNS Neuroscience & Therapeutics

Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation

(2016) Mohd Waseem Akhtar et al.   Nature Communications

Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer’s disease

(2016) Peter Koppensteiner et al.   Scientific Reports

A novel protective mechanism for mitochondrial aldehyde dehydrogenase (ALDH2) in type i diabetes-induced cardiac dysfunction: Role of AMPK-regulated autophagy

(2015) Yuli Guo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Luteolin as an anti-inflammatory and neuroprotective agent: A brief review

(2015) Seyed Fazel Nabavi et al.   BRAIN RESEARCH BULLETIN

S-allyl cysteine activates the Nrf2-dependent antioxidant response and protects neurons against ischemic injuryin vitroandin vivo

(2015) Huanying Shi et al.   JOURNAL OF NEUROCHEMISTRY

Enzymatic Hydrolysis of Oleuropein from Olea europea (Olive) Leaf Extract and Antioxidant Activities

(2015) Jiao-Jiao Yuan et al.   MOLECULES

Olive Leaf Extracts Protect Cardiomyocytes against 4-Hydroxynonenal-Induced Toxicity In Vitro: Comparison with Oleuropein, Hydroxytyrosol, and Quercetin

(2014) Elif Bali et al.   PLANTA MEDICA

Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T

(2013) Daniel R. Beriault et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Effects of exposure to high glucose on primary cultured hippocampal neurons: involvement of intracellular ROS accumulation

(2013) Di Liu et al.   NEUROLOGICAL SCIENCES

The rutin catabolic pathway with special emphasis on quercetinase

(2010) Sylvain Tranchimand et al.   BIODEGRADATION

Ghrelin Modulates Insulin Sensitivity and Tau Phosphorylation in High Glucose-Induced Hippocampal Neurons

(2010) Ying Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Long-term exposure to high glucose induces changes in the content and distribution of some exocytotic proteins in cultured hippocampal neurons

(2010) J.M. Gaspar et al.   NEUROSCIENCE

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

A facile method for expression and purification of the Alzheimer’s disease-associated amyloid β-peptide

(2009) Dominic M. Walsh et al.   FEBS Journal

Distribution and Biological Activities of the Flavonoid Luteolin

(2009) Miguel Lopez-Lazaro   MINI-REVIEWS IN MEDICINAL CHEMISTRY