Isorhynchophylline Relieves Ferroptosis-Induced Nerve Damage after Intracerebral Hemorrhage Via miR-122-5p/TP53/SLC7A11 Pathway

MicroRNA-122 aggravates angiotensin II-mediated apoptosis and autophagy imbalance in rat aortic adventitial fibroblasts via the modulation of SIRT6-elabela-ACE2 signaling

(2020) Juan-Juan Song et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Isorhynchophylline exerts anti-inflammatory and anti-oxidative activities in LPS-stimulated murine alveolar macrophages

(2019) Zheng Zhou et al.   LIFE SCIENCES

HOXC13-AS-miR-122-5p-SATB1-C-Myc feedback loop promotes migration, invasion and EMT process in glioma

(2019) Ning Liu et al.   OncoTargets and Therapy

lncRNA LINC01494 Promotes Proliferation, Migration And Invasion In Glioma Through miR-122-5p/CCNG1 Axis

(2019) Chang Li et al.   OncoTargets and Therapy

Isorhynchophylline exerts anti-asthma effects in mice by inhibiting the proliferation of airway smooth muscle cells: The involvement of miR-200a-mediated FOXC1/NF-κB pathway

(2019) Jinyue Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21–5p and miR-331–5p

(2019) Heng-Sheng Zhang et al.   LIFE SCIENCES

Peroxiredoxin 5 prevents iron overload-induced neuronal death by inhibiting mitochondrial fragmentation and endoplasmic reticulum stress in mouse hippocampal HT-22 cells

(2018) Dong Gil Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats

(2018) Dawei Sun et al.   Cell Death & Disease

α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice

(2018) Yan-Hui Zhang et al.   Redox Biology

Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway

(2018) Shi-feng Chu et al.   ACTA PHARMACOLOGICA SINICA

Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis

(2018) Tetsuro Ishii et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Mutant p53-Targeting Compound APR-246 Induces ROS-Modulating Genes in Breast Cancer Cells

(2018) Naoise C. Synnott et al.   Translational Oncology

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

(2017) Marietta Zille et al.   STROKE

miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model

(2017) Merrie Mosedale et al.   TOXICOLOGICAL SCIENCES

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Iron Export through the Transporter Ferroportin 1 Is Modulated by the Iron Chaperone PCBP2

(2016) Izumi Yanatori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The protective effect of human platelet lysate in models of neurodegenerative disease: involvement of the Akt and MEK pathways

(2016) Flore Gouel et al.   Journal of Tissue Engineering and Regenerative Medicine

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

(2016) Sebastian Doll et al.   Nature Chemical Biology

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC

(2016) Bruce Do Van et al.   NEUROBIOLOGY OF DISEASE

Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes

(2016) Inês G. Mollet et al.   PLoS One

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Urinary metabolites of isorhynchophylline in rats and their neuroprotective activities in the HT22 cell assay

(2014) Fangfang Chen et al.   FITOTERAPIA

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke

(2013) Rachel E. Speer et al.   FREE RADICAL BIOLOGY AND MEDICINE

Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine

(2013) Jianfang Chen et al.   PLoS One

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Rhynchophylline prevents cardiac dysfunction and improves survival in lipopolysaccharide-challenged mice via suppressing macrophage I-κBα phosphorylation

(2012) Wenjuan Cao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Astrocyte-Specific Expression of Survivin after Intracerebral Hemorrhage in Mice: A Possible Role in Reactive Gliosis?

(2012) Sangeetha Sukumari-Ramesh et al.   JOURNAL OF NEUROTRAUMA

Rhynchophylline Attenuates LPS-induced Pro-inflammatory Responses through Down-regulation of MAPK/NF-κB Signaling Pathways in Primary Microglia

(2012) Yu Song et al.   PHYTOTHERAPY RESEARCH

Prolonged exposure to ammonia increases extracellular glutamate in cultured rat astrocytes

(2009) Kentaro Ohara et al.   NEUROSCIENCE LETTERS