Synergizing Off-Target Predictions for In Silico Insights of CENH3 Knockout in Cannabis through CRISPR/Cas

Season‐long characterization of high‐cannabinoid hemp ( Cannabis sativa L.) reveals variation in cannabinoid accumulation, flowering time, and disease resistance

(2021) George M. Stack et al.   Global Change Biology Bioenergy

sgRNACNN: identifying sgRNA on-target activity in four crops using ensembles of convolutional neural networks

(2021) Mengting Niu et al.   PLANT MOLECULAR BIOLOGY

Application of Machine Learning Algorithms in Plant Breeding: Predicting Yield From Hyperspectral Reflectance in Soybean

(2021) Mohsen Yoosefzadeh-Najafabadi et al.   Frontiers in Plant Science

The Past, Present and Future of Cannabis sativa Tissue Culture

(2021) Adrian S. Monthony et al.   Plants-Basel

A hybrid model based on general regression neural network and fruit fly optimization algorithm for forecasting and optimizing paclitaxel biosynthesis in Corylus avellana cell culture

(2021) Mina Salehi et al.   Plant Methods

CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine

(2020) Filipe V. Jacinto et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

In vitro-based doubled haploid production: recent improvements

(2020) Mohsen Niazian et al.   EUPHYTICA

Modified Nodal Cuttings and Shoot Tips Protocol for Rapid Regeneration of Cannabis sativa L.

(2020) Tomasz Wróbel et al.   Journal of Natural Fibers

Development of a Direct in vitro Plant Regeneration Protocol From Cannabis sativa L. Seedling Explants: Developmental Morphology of Shoot Regeneration and Ploidy Level of Regenerated Plants

(2020) Alberto Galán-Ávila et al.   Frontiers in Plant Science

Artificial polyploidy induction for improvement of ornamental and medicinal plants

(2020) Mohsen Niazian et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Development of support vector machine-based model and comparative analysis with artificial neural network for modeling the plant tissue culture procedures: effect of plant growth regulators on somatic embryogenesis of chrysanthemum, as a case study

(2020) Mohsen Hesami et al.   Plant Methods

Machine learning: A powerful tool for gene function prediction in plants

(2020) Elizabeth H. Mahood et al.   Applications in Plant Sciences

Application of Artificial Neural Network for Modeling and Studying In Vitro Genotype-Independent Shoot Regeneration in Wheat

(2020) Mohsen Hesami et al.   Applied Sciences-Basel

Application of artificial intelligence models and optimization algorithms in plant cell and tissue culture

(2020) Mohsen Hesami et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

It Is Our Turn to Get Cannabis High: Put Cannabinoids in Food and Health Baskets

(2020) Seyed Alireza Salami et al.   MOLECULES

Applications of CRISPR–Cas in agriculture and plant biotechnology

(2020) Haocheng Zhu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Forecasting and optimizing Agrobacterium-mediated genetic transformation via ensemble model- fruit fly optimization algorithm: A data mining approach using chrysanthemum databases

(2020) Mohsen Hesami et al.   PLoS One

The application of artificial neural networks in modeling and predicting the effects of melatonin on morphological responses of citrus to drought stress

(2020) Marziyeh Jafari et al.   PLoS One

Potentials and Challenges of Genomics for Breeding Cannabis Cultivars

(2020) Gianni Barcaccia et al.   Frontiers in Plant Science

Machine Learning for Plant Breeding and Biotechnology

(2020) Mohsen Niazian et al.   Agriculture-Basel

Recent advances in cannabis biotechnology

(2020) Mohsen Hesami et al.   INDUSTRIAL CROPS AND PRODUCTS

Biotechnological Approaches on Two High CBD and CBG Cannabis sativa L. (Cannabaceae) Varieties: In Vitro Regeneration and Phytochemical Consistency Evaluation of Micropropagated Plants Using Quantitative 1H-NMR

(2020) Kostas Ioannidis et al.   MOLECULES

Recent advances in Cannabis sativa genomics research

(2020) Bhavna Hurgobin et al.   NEW PHYTOLOGIST

Application of genetics and biotechnology for improving medicinal plants

(2019) Mohsen Niazian   PLANTA

One-step genome editing of elite crop germplasm during haploid induction

(2019) Timothy Kelliher et al.   NATURE BIOTECHNOLOGY

Development of a Haploid-Inducer Mediated Genome Editing System for Accelerating Maize Breeding

(2019) Baobao Wang et al.   Molecular Plant

The Complex Interactions Between Flowering Behavior and Fiber Quality in Hemp

(2019) Elma M. J. Salentijn et al.   Frontiers in Plant Science

Machine learning approaches and their current application in plant molecular biology: A systematic review

(2019) Jose Cleydson F. Silva et al.   PLANT SCIENCE

An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools

(2019) Jun Wang et al.   RNA Biology

Application of Adaptive Neuro-Fuzzy Inference System-Non-dominated Sorting Genetic Algorithm-II (ANFIS-NSGAII) for Modeling and Optimizing Somatic Embryogenesis of Chrysanthemum

(2019) Mohsen Hesami et al.   Frontiers in Plant Science

The deposition of CENH3 in maize is stringently regulated

(2019) Chao Feng et al.   PLANT JOURNAL

Modeling and Optimizing Medium Composition for Shoot Regeneration of Chrysanthemum via Radial Basis Function-Non-dominated Sorting Genetic Algorithm-II (RBF-NSGAII)

(2019) Mohsen Hesami et al.   Scientific Reports

OUP accepted manuscript

(2018)   BIOINFORMATICS

CRISPR off-target analysis in genetically engineered rats and mice

(2018) Keith R. Anderson et al.   NATURE METHODS

Synergizing CRISPR/Cas9 off-target predictions for ensemble insights and practical applications

(2018) Shixiong Zhang et al.   BIOINFORMATICS

Mathematical and computational analysis of CRISPR Cas9 sgRNA off-target homologies

(2017) Michael Zhou et al.   International Journal of Biomathematics

Conserved molecular structure of the centromeric histone CENH3 in Secale and its phylogenetic relationships

(2017) E. V. Evtushenko et al.   Scientific Reports

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

(2016) Ciaran M Lee et al.   MOLECULAR THERAPY

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Comparison of different regression models and validation techniques for the assessment of wheat leaf area index from hyperspectral data

(2015) Bastian Siegmann et al.   INTERNATIONAL JOURNAL OF REMOTE SENSING

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors

(2015) Xiaoling Wang et al.   NATURE BIOTECHNOLOGY

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

(2015) Daesik Kim et al.   NATURE METHODS

Off-target Effects in CRISPR/Cas9-mediated Genome Engineering

(2015) Xiao-Hui Zhang et al.   Molecular Therapy-Nucleic Acids

CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites

(2014) Yuki Naito et al.   BIOINFORMATICS

CasOT: a genome-wide Cas9/gRNA off-target searching tool

(2014) A. Xiao et al.   BIOINFORMATICS

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

(2014) S. Bae et al.   BIOINFORMATICS

Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

(2014) John G Doench et al.   NATURE BIOTECHNOLOGY

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

(2014) Shengdar Q Tsai et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

(2014) Y. Lin et al.   NUCLEIC ACIDS RESEARCH

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY