Effects of Long-Term Environmental Enrichment on Anxiety, Memory, Hippocampal Plasticity and Overall Brain Gene Expression in C57BL6 Mice

Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice

(2018) Yoelvis García-Mesa et al.   JOURNAL OF ALZHEIMERS DISEASE

Long-Term Exercise Modulates Hippocampal Gene Expression in Senescent Female Mice

(2018) María Jesús Alvarez-López et al.   JOURNAL OF ALZHEIMERS DISEASE

Environmental Enrichment Lessens Cognitive Decline in APP23 Mice Without Affecting Brain Sirtuin Expression

(2018) Letizia Polito et al.   JOURNAL OF ALZHEIMERS DISEASE

Acute Aerobic Exercise Increases Brain-Derived Neurotrophic Factor Levels in Elderly with Alzheimer's Disease

(2018) Flávia Gomes de Melo Coelho et al.   JOURNAL OF ALZHEIMERS DISEASE

Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model

(2016) M Hüttenrauch et al.   Translational Psychiatry

Physical activity and dementia: Long-term follow-up study of adult twins

(2015) Paula Iso-Markku et al.   ANNALS OF MEDICINE

Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis

(2015) Alexander Garthe et al.   HIPPOCAMPUS

Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics

(2015) Shailaja Kishan Rao et al.   NEUROBIOLOGY OF DISEASE

Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline

(2014) Deheng Wang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Potential for primary prevention of Alzheimer's disease: an analysis of population-based data

(2014) Sam Norton et al.   LANCET NEUROLOGY

Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain

(2014) Susana Revilla et al.   NEUROPHARMACOLOGY

Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing

(2014) Yvonne Bouter et al.   Frontiers in Aging Neuroscience

Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease

(2014) J. Carson Smith et al.   Frontiers in Aging Neuroscience

Homeostatic regulation of adult hippocampal neurogenesis in aging rats: long-term effects of early exercise

(2014) Christina M. Merkley et al.   Frontiers in Neuroscience

Changes in the brain expression of alpha-2 subunits of the GABA-A receptor after chronic restraint stress in low- and high-anxiety rats

(2013) Aleksandra Wisłowska-Stanek et al.   BEHAVIOURAL BRAIN RESEARCH

Enriched environment induces higher CNPase positive cells in aged rat hippocampus

(2013) Yuan-yu Zhao et al.   NEUROSCIENCE LETTERS

Long-Term Exercise Is a Potent Trigger for ΔFosB Induction in the Hippocampus along the dorso–ventral Axis

(2013) Takeshi Nishijima et al.   PLoS One

Structural Dynamics of Dendritic Spines are Influenced by an Environmental Enrichment: An In Vivo Imaging Study

(2012) Christian K.E. Jung et al.   CEREBRAL CORTEX

Running is the neurogenic and neurotrophic stimulus in environmental enrichment

(2011) T. Kobilo et al.   LEARNING & MEMORY

Spatial memory is improved by aerobic and resistance exercise through divergent molecular mechanisms

(2011) R.C. Cassilhas et al.   NEUROSCIENCE

Enriched environment effects on behavior, memory and BDNF in low and high exploratory mice

(2011) Vanessa Kazlauckas et al.   PHYSIOLOGY & BEHAVIOR

Exercise training increases size of hippocampus and improves memory

(2011) K. I. Erickson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice

(2010) Marie-Caroline Cotel et al.   NEUROBIOLOGY OF AGING

Swimming exercise effects on the expression of HSP70 and iNOS in hippocampus and prefrontal cortex in combined stress

(2010) Xin Liu et al.   NEUROSCIENCE LETTERS

Additive effects of physical exercise and environmental enrichment on adult hippocampal neurogenesis in mice

(2010) Klaus Fabel   Frontiers in Neuroscience

An anxiety-like phenotype in mice selectively bred for aggression

(2009) Derrick L. Nehrenberg et al.   BEHAVIOURAL BRAIN RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Exercise can increase small heat shock proteins (sHSP) and pre- and post-synaptic proteins in the hippocampus

(2008) Shuxin Hu et al.   BRAIN RESEARCH

Heat shock response relieves ER stress

(2008) Yu Liu et al.   EMBO JOURNAL