Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the PREDIGT score

CSF biomarkers associated with disease heterogeneity in early Parkinson’s disease: the Parkinson’s Progression Markers Initiative study

(2016) Ju-Hee Kang et al.   ACTA NEUROPATHOLOGICA

External Validation of the STONE Score, a Clinical Prediction Rule for Ureteral Stone: An Observational Multi-institutional Study

(2016) Ralph C. Wang et al.   ANNALS OF EMERGENCY MEDICINE

Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database

(2016) Cynthia J. Grondin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study

(2016) Joanne Trinh et al.   LANCET NEUROLOGY

Modifiers of LRRK2 parkinsonism: new therapeutic targets

(2016) Owen A Ross et al.   LANCET NEUROLOGY

Similar α-Synuclein staining in the colon mucosa in patients with Parkinson's disease and controls

(2016) Laurent Antunes et al.   MOVEMENT DISORDERS

Lewy body pathology involves the olfactory cells in Parkinson's disease and related disorders

(2016) Yuko Saito et al.   MOVEMENT DISORDERS

A review of disease progression models of Parkinson's disease and applications in clinical trials

(2016) Charles S. Venuto et al.   MOVEMENT DISORDERS

Increased peripheral inflammation in asymptomatic leucine-rich repeat kinase 2 mutation carriers

(2016) Nicolas Dzamko et al.   MOVEMENT DISORDERS

Biomarkers in Parkinson's disease: From pathophysiology to early diagnosis

(2016) Paolo Calabresi et al.   MOVEMENT DISORDERS

Motor and Nonmotor Features of Carriers of the p.A53T Alpha-Synuclein Mutation: A Longitudinal Study

(2016) Dimitra Papadimitriou et al.   MOVEMENT DISORDERS

Nomenclature of genetic movement disorders: Recommendations of the international Parkinson and movement disorder society task force

(2016) Connie Marras et al.   MOVEMENT DISORDERS

The Evolution of Genetics: Alzheimer’s and Parkinson’s Diseases

(2016) Andrew Singleton et al.   NEURON

Head injury at early ages is associated with risk of Parkinson's disease

(2016) Kathryn M. Taylor et al.   PARKINSONISM & RELATED DISORDERS

Conjugal parkinsonism – Clinical, pathology and genetic study. No evidence of person-to-person transmission

(2016) Ali H. Rajput et al.   PARKINSONISM & RELATED DISORDERS

Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses

(2016) Vanesa Bellou et al.   PARKINSONISM & RELATED DISORDERS

Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms

(2016) Valeria D. Felice et al.   PARKINSONISM & RELATED DISORDERS

Gut microbiome in health and disease: Linking the microbiome–gut–brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases

(2016) Shivani Ghaisas et al.   PHARMACOLOGY & THERAPEUTICS

Genetic Factors Are Not the Major Causes of Chronic Diseases

(2016) Stephen M. Rappaport   PLoS One

Leucine-rich repeat kinase 2 and Parkinson's disease

(2016) Un-Beom Kang et al.   PROTEOMICS

Epidemiology of Parkinson's disease

(2016) A. Elbaz et al.   REVUE NEUROLOGIQUE

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

(2016) Deepak Kumar Vijaya Kumar et al.   Science Translational Medicine

Measuring Burden of Unhealthy Behaviours Using a Multivariable Predictive Approach: Life Expectancy Lost in Canada Attributable to Smoking, Alcohol, Physical Inactivity, and Diet

(2016) Douglas G. Manuel et al.   PLOS MEDICINE

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy

(2016) Vinicius M. Fava et al.   PLoS Neglected Tropical Diseases

The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

(2016) Kelly J. Pittman et al.   PLoS Pathogens

Wells criteria for DVT is a reliable clinical tool to assess the risk of deep venous thrombosis in trauma patients

(2016) Shrey Modi et al.   World Journal of Emergency Surgery

Oral Anticoagulant Therapy Prescription in Patients With Atrial Fibrillation Across the Spectrum of Stroke Risk

(2016) Jonathan C. Hsu et al.   JAMA Cardiology

Protective effect of vagotomy suggests source organ for Parkinson disease

(2015) Madison T. Gray et al.   ANNALS OF NEUROLOGY

Vagotomy and subsequent risk of Parkinson's disease

(2015) Elisabeth Svensson et al.   ANNALS OF NEUROLOGY

Association between α-synuclein blood transcripts and early, neuroimaging-supported Parkinson’s disease

(2015) Joseph J. Locascio et al.   BRAIN

The New Pooled Cohort Equations Risk Calculator

(2015) David Preiss et al.   CANADIAN JOURNAL OF CARDIOLOGY

Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration

(2015) João P. L. Daher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alpha-Synuclein Expression Restricts RNA Viral Infections in the Brain

(2015) Erica L. Beatman et al.   JOURNAL OF VIROLOGY

Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study

(2015) Mike A Nalls et al.   LANCET NEUROLOGY

Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings

(2015) Lama M. Chahine et al.   MOVEMENT DISORDERS

MDS clinical diagnostic criteria for Parkinson's disease

(2015) Ronald B. Postuma et al.   MOVEMENT DISORDERS

MDS research criteria for prodromal Parkinson's disease

(2015) Daniela Berg et al.   MOVEMENT DISORDERS

LRRK2 and Nod2 promote lysozyme sorting in Paneth cells

(2015) Juliana D B Rocha et al.   NATURE IMMUNOLOGY

Age-specific penetrance ofLRRK2G2019S in the Michael J. Fox Ashkenazi Jewish LRRK2 Consortium

(2015) Karen Marder et al.   NEUROLOGY

Differential effects of severe vs mild GBA mutations on Parkinson disease

(2015) Z. Gan-Or et al.   NEUROLOGY

The association between infectious burden and Parkinson's disease: A case-control study

(2015) Xian-Le Bu et al.   PARKINSONISM & RELATED DISORDERS

Diagnostic prediction models for suspected pulmonary embolism: systematic review and independent external validation in primary care

(2015) Janneke M T Hendriksen et al.   BMJ-British Medical Journal

Linking Smoking, Coffee, Urate, and Parkinson’s Disease – A Role for Gut Microbiota?

(2015) Filip Scheperjans et al.   Journal of Parkinsons Disease

Diagnostic prediction models for suspected pulmonary embolism: systematic review and independent external validation in primary care

(2015) Janneke M T Hendriksen et al.   BMJ-British Medical Journal

Clinical Correlations With Lewy Body Pathology inLRRK2-Related Parkinson Disease

(2015) Lorraine V. Kalia et al.   JAMA Neurology

The role ofSNCAandMAPTin Parkinson disease andLRRK2parkinsonism in the Tunisian Arab-Berber population

(2014) J. Trinh et al.   EUROPEAN JOURNAL OF NEUROLOGY

Studying the Elusive Environment in Large Scale

(2014) Chirag J. Patel et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Medical and molecular perspectives into a forgotten epidemic: Encephalitis lethargica, viruses, and high-throughput sequencing

(2014) Dennis Tappe et al.   JOURNAL OF CLINICAL VIROLOGY

Alpha-synuclein repeat variants and survival in Parkinson's disease

(2014) Sun Ju Chung et al.   MOVEMENT DISORDERS

Gut feelings about smoking and coffee in Parkinson's disease

(2014) Pascal Derkinderen et al.   MOVEMENT DISORDERS

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

(2014) Mike A Nalls et al.   NATURE GENETICS

LRRK2 mutations in Parkinson's disease: Confirmation of a gender effect in the Italian population

(2014) Roberto Cilia et al.   PARKINSONISM & RELATED DISORDERS

Nonmotor Symptoms in LRRK2 G2019S Associated Parkinson’s Disease

(2014) Carles Gaig et al.   PLoS One

Comparison of Parkinson Risk in Ashkenazi Jewish Patients With Gaucher Disease andGBAHeterozygotes

(2014) Roy N. Alcalay et al.   JAMA Neurology

Redox biology: Interface of the exposome with the proteome, epigenome and genome

(2014) Young-Mi Go et al.   Redox Biology

Chronic Traumatic Encephalopathy: Where Are We and Where Are We Going?

(2013) Jesse Mez et al.   Current Neurology and Neuroscience Reports

Genetic assessment of familial and early-onset Parkinson's disease in a Greek population

(2013) M. Bozi et al.   EUROPEAN JOURNAL OF NEUROLOGY

Joint Analysis for Integrating Two Related Studies of Different Data Types and Different Study Designs Using Hierarchical Modeling Approaches

(2013) Rui Li et al.   HUMAN HEREDITY

Alpha-synuclein in the appendiceal mucosa of neurologically intact subjects

(2013) Madison T. Gray et al.   MOVEMENT DISORDERS

Comment to letter: “Identical twins with LRRK2 mutation discordant for Parkinson's disease”

(2013) Christopher H. Hawkes   MOVEMENT DISORDERS

Population-specific frequencies forLRRK2susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO-PD) consortium

(2013) Michael G. Heckman et al.   MOVEMENT DISORDERS

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

(2013) David J. Irwin et al.   NATURE REVIEWS NEUROSCIENCE

Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort

(2013) B. Mollenhauer et al.   NEUROLOGY

Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study

(2013) H. Ding et al.   NEUROLOGY

Leucine-Rich Repeat Kinase 2 (LRRK2)-Deficient Rats Exhibit Renal Tubule Injury and Perturbations in Metabolic and Immunological Homeostasis

(2013) Daniel Ness et al.   PLoS One

An emerging role for LRRK2 in the immune system

(2012) Nicolas Dzamko et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

(2012) Rui Chen et al.   CELL

Considerations Regarding the Etiology and Future Treatment of Autosomal Recessive Versus Idiopathic Parkinson Disease

(2012) Tohru Kitada et al.   Current Treatment Options in Neurology

Novel One-step Immunoassays to Quantify α-Synuclein

(2012) Michael Bidinosti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRRK2 Inhibition Attenuates Microglial Inflammatory Responses

(2012) M. S. Moehle et al.   JOURNAL OF NEUROSCIENCE

Caffeine and risk of Parkinson's disease in a large cohort of men and women

(2012) Natalia Palacios et al.   MOVEMENT DISORDERS

Identical twins with Leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease

(2012) Georgia Xiromerisiou et al.   MOVEMENT DISORDERS

Total CSF α-synuclein is lower in de novo Parkinson patients than in healthy subjects

(2012) Brit Mollenhauer et al.   NEUROSCIENCE LETTERS

Neuropathology underlying clinical variability in patients with synucleinopathies

(2011) Glenda M. Halliday et al.   ACTA NEUROPATHOLOGICA

Acid β-glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α-synuclein processing

(2011) Valerie Cullen et al.   ANNALS OF NEUROLOGY

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

(2011) Martin C. Herzig et al.   HUMAN MOLECULAR GENETICS

Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures

(2011) Mansoureh Hakimi et al.   JOURNAL OF NEURAL TRANSMISSION

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

(2011)   LANCET

Modelling of Parkinson's disease in mice

(2011) Marie-Françoise Chesselet et al.   LANCET NEUROLOGY

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

Clinical features, with video documentation, of the original familial lewy body parkinsonism caused by α-synuclein triplication (Iowa kindred)

(2011) Katrina Gwinn et al.   MOVEMENT DISORDERS

Neuroinflammation in Parkinson's disease

(2011) Etienne C. Hirsch et al.   PARKINSONISM & RELATED DISORDERS

CNS expression of glucocerebrosidase corrects  -synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

(2011) S. P. Sardi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson’s disease

(2010) Kelly Del Tredici et al.   ACTA NEUROPATHOLOGICA

Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease

(2010) Todd L. Edwards et al.   ANNALS OF HUMAN GENETICS

When Does Parkinson Disease Start?

(2010) Rodolfo Savica et al.   ARCHIVES OF NEUROLOGY

Biomarker research in Parkinson’s disease: objective measures needed for patient stratification in future cause-directed trials

(2010) Michael G Schlossmacher et al.   Biomarkers in Medicine

Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated α-synuclein gene mutations precede central nervous system changes

(2010) Yien-Ming Kuo et al.   HUMAN MOLECULAR GENETICS

After half a century of research on smoking and PD, where do we go now?

(2010) B. Ritz et al.   NEUROLOGY

Absence of α-synuclein pathology in postencephalitic parkinsonism

(2009) Kurt A. Jellinger   ACTA NEUROPATHOLOGICA

Impaired dopamine release and synaptic plasticity in the striatum ofParkin−/− mice

(2009) Tohru Kitada et al.   JOURNAL OF NEUROCHEMISTRY

Pathologic Modifications of α-Synuclein in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Squirrel Monkeys

(2009) Alison L. McCormack et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Neurochemical biomarkers in the differential diagnosis of movement disorders

(2009) Brit Mollenhauer et al.   MOVEMENT DISORDERS

Incidence and remaining lifetime risk of Parkinson disease in advanced age

(2009) J. A. Driver et al.   NEUROLOGY

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

(2009) E. Sidransky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Conjugal Parkinsonism and Parkinson disease: A case series with environmental risk factor analysis

(2009) Allison W. Willis et al.   PARKINSONISM & RELATED DISORDERS

A timeline for Parkinson's disease

(2009) Christopher H. Hawkes et al.   PARKINSONISM & RELATED DISORDERS

The Olfactory System and Its Disorders

(2009) Richard Doty   SEMINARS IN NEUROLOGY

The olfactory vector hypothesis of neurodegenerative disease: Is it viable?

(2008) Richard L. Doty   ANNALS OF NEUROLOGY

Viral parkinsonism

(2008) Haeman Jang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Environmental exposure measurement in cancer epidemiology

(2008) C. P. Wild   MUTAGENESIS

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Invited Article: Nervous system pathology in sporadic Parkinson disease

(2008) H. Braak et al.   NEUROLOGY

A Parkinsonian Syndrome in Methcathinone Users and the Role of Manganese

(2008) Ainārs Stepens et al.   NEW ENGLAND JOURNAL OF MEDICINE