LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
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Title
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 20, Issue 21, Pages 4209-4223
Publisher
Oxford University Press (OUP)
Online
2011-08-10
DOI
10.1093/hmg/ddr348
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Note: Only part of the references are listed.- Pathophysiological Role of Autophagy: Lesson from Autophagy-Deficient Mouse Models
- (2011) Yoshinobu ICHIMURA et al. EXPERIMENTAL ANIMALS
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- Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas
- (2011) B. D. Looyenga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
- (2010) Nicolas Dzamko et al. BIOCHEMICAL JOURNAL
- Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development
- (2010) Sabrina Zechel et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
- (2010) Stephan Gehrke et al. NATURE
- Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
- (2010) Byoung Dae Lee et al. NATURE MEDICINE
- Autophagy gone awry in neurodegenerative diseases
- (2010) Esther Wong et al. NATURE NEUROSCIENCE
- The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
- (2010) Mark R. Cookson NATURE REVIEWS NEUROSCIENCE
- The Parkinson's Disease Associated LRRK2 Exhibits Weaker In Vitro Phosphorylation of 4E-BP Compared to Autophosphorylation
- (2010) Azad Kumar et al. PLoS One
- Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of -synuclein, and apoptotic cell death in aged mice
- (2010) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Involvement of type II pneumocytes in the pathogenesis of chronic obstructive pulmonary disease
- (2010) Chun-zhen Zhao et al. RESPIRATORY MEDICINE
- GTPase Activity Plays a Key Role in the Pathobiology of LRRK2
- (2010) Yulan Xiong et al. PLoS Genetics
- I2020T leucine-rich repeat kinase 2, the causative mutant molecule of familial Parkinson’s disease, has a higher intracellular degradation rate than the wild-type molecule
- (2009) Etsuro Ohta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
- (2009) Juliane Neumann et al. BRAIN
- The Closer we Look the more we See? Quantitative Microscopic Analysis of the Pulmonary Surfactant System
- (2009) Matthias Ochs CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- LRRK2 in Parkinson’s disease: biochemical functions
- (2009) Vasanti S. Anand et al. FEBS Journal
- LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
- (2009) Javier Alegre-Abarrategui et al. HUMAN MOLECULAR GENETICS
- mTORβ Splicing Isoform Promotes Cell Proliferation and Tumorigenesis
- (2009) Ganna Panasyuk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Kinase Activity of Rip2 Determines Its Stability and Consequently Nod1- and Nod2-mediated Immune Responses
- (2009) Chiara Nembrini et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Abnormal Localization of Leucine-Rich Repeat Kinase 2 to the Endosomal-Lysosomal Compartment in Lewy Body Disease
- (2009) Shinji Higashi et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
- (2009) Wataru Satake et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Glucocerebrosidase mutations are not a common risk factor for Parkinson disease in North Africa
- (2009) Kenya Nishioka et al. NEUROSCIENCE LETTERS
- Receptor-mediated endocytosis in renal proximal tubule
- (2009) Erik Ilsø Christensen et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Disorders of Lysosome-Related Organelle Biogenesis: Clinical and Molecular Genetics
- (2008) Marjan Huizing et al. Annual Review of Genomics and Human Genetics
- Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
- (2008) Yuzuru Imai et al. EMBO JOURNAL
- LRRK2 regulates synaptic vesicle endocytosis
- (2008) Narae Shin et al. EXPERIMENTAL CELL RESEARCH
- Investigation of leucine-rich repeat kinase 2
- (2008) Vasanti S. Anand et al. FEBS Journal
- Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
- (2008) Edward D. Plowey et al. JOURNAL OF NEUROCHEMISTRY
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
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