Shutoff of host transcription triggers a toxin-antitoxin system to cleave phage RNA and abort infection

The arms race between bacteria and their phage foes

(2020) Hannah G. Hampton et al.   NATURE

A Simple, Cost-Effective, and Robust Method for rRNA Depletion in RNA-Sequencing Studies

(2020) Peter H. Culviner et al.   mBio

Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin

(2020) Michele LeRoux et al.   MOLECULAR CELL

A Primary Physiological Role of Toxin/Antitoxin Systems Is Phage Inhibition

(2020) Sooyeon Song et al.   Frontiers in Microbiology

Abortive Infection: Bacterial Suicide as an Antiviral Immune Strategy

(2020) Anna Lopatina et al.   Annual Review of Virology

Diverse enzymatic activities mediate antiviral immunity in prokaryotes

(2020) Linyi Gao et al.   SCIENCE

Predicting microbial growth in a mixed culture from growth curve data

(2019) Yoav Ram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reassessing the Role of the Type II MqsRA Toxin-Antitoxin System in Stress Response and Biofilm Formation: mqsA Is Transcriptionally Uncoupled from mqsR

(2019) Nathan Fraikin et al.   mBio

Global Analysis of the E. coli Toxin MazF Reveals Widespread Cleavage of mRNA and the Inhibition of rRNA Maturation and Ribosome Biogenesis

(2018) Peter H. Culviner et al.   MOLECULAR CELL

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

(2018) Alexander Harms et al.   MOLECULAR CELL

Systematic discovery of antiphage defense systems in the microbial pangenome

(2018) Shany Doron et al.   SCIENCE

The E. coli Global Regulator DksA Reduces Transcription during T4 Infection

(2018) Jennifer Patterson-West et al.   Viruses-Basel

The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity

(2018) Francesca L. Short et al.   Scientific Reports

Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells

(2017) Alexander Harms et al.   mBio

RnlB Antitoxin of the Escherichia coli RnlA-RnlB Toxin–Antitoxin Module Requires RNase HI for Inhibition of RnlA Toxin Activity

(2017) Kenta Naka et al.   Toxins

tRNA is a new target for cleavage by a MazF toxin

(2016) Jason M. Schifano et al.   NUCLEIC ACIDS RESEARCH

CRISPR-mediated control of the bacterial initiation of replication

(2016) Jakub Wiktor et al.   NUCLEIC ACIDS RESEARCH

A widespread bacteriophage abortive infection system functions through a Type IV toxin–antitoxin mechanism

(2014) Ron L. Dy et al.   NUCLEIC ACIDS RESEARCH

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

(2014) S. Helaine et al.   SCIENCE

Discovery of Functional Toxin/Antitoxin Systems in Bacteria by Shotgun Cloning

(2013) Hila Sberro et al.   MOLECULAR CELL

Dmd of bacteriophage T4 functions as an antitoxin against Escherichia coli LsoA and RnlA toxins

(2012) Yuichi Otsuka et al.   MOLECULAR MICROBIOLOGY

Structure and activity of AbiQ, a lactococcal endoribonuclease belonging to the type III toxin-antitoxin system

(2012) Julie E. Samson et al.   MOLECULAR MICROBIOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Identification and classification of bacterial Type III toxin–antitoxin systems encoded in chromosomal and plasmid genomes

(2012) Tim R. Blower et al.   NUCLEIC ACIDS RESEARCH

Selectivity and self-assembly in the control of a bacterial toxin by an antitoxic noncoding RNA pseudoknot

(2012) F. L. Short et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A processed noncoding RNA regulates an altruistic bacterial antiviral system

(2011) Tim R Blower et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

Escherichia coli rnlA and rnlB Compose a Novel Toxin-Antitoxin System

(2010) M. Koga et al.   GENETICS

Transcriptional control in the prereplicative phase of T4 development

(2010) Deborah M Hinton   Virology Journal

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli

(2010) Tobias Dörr et al.   PLOS BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

The phage abortive infection system, ToxIN, functions as a protein–RNA toxin–antitoxin pair

(2009) Peter C. Fineran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA