Nano-encapsulation of hydroxytyrosol into formulated nanogels improves therapeutic effects against hepatic steatosis: An in vitro study

NAFLD 2020: The State of the Disease

(2020) Thomas G. Cotter et al.   GASTROENTEROLOGY

Quercetin and hydroxytyrosol as modulators of hepatic steatosis: A NAFLD‐on‐a‐chip study

(2020) Manuele Gori et al.   BIOTECHNOLOGY AND BIOENGINEERING

Hepatoprotective effects of silymarin coated gold nanoparticles in experimental cholestasis

(2020) Simona Clichici et al.   Materials Science & Engineering C-Materials for Biological Applications

Functionalized nanogel for treating activated astrocytes in spinal cord injury

(2020) Simonetta Papa et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Interleukin-22 Gene Delivery in the Liver by Poly-Metformin and Penetratin-Based Hybrid Nanoparticles to Treat Non-Alcoholic Fatty Liver Disease

(2019) Wenjing Zai et al.   ACS Applied Materials & Interfaces

Intravenous sustained-release nifedipine ameliorates nonalcoholic fatty liver disease by restoring autophagic clearance

(2019) Solji Lee et al.   BIOMATERIALS

Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis

(2019) Surbhi Dogra et al.   Nanomedicine-Nanotechnology Biology and Medicine

Beyond the Scavenging of Reactive Oxygen Species (ROS): Direct Effect of Cerium Oxide Nanoparticles in Reducing Fatty Acids Content in an In Vitro Model of Hepatocellular Steatosis

(2019) Marina Parra-Robert et al.   Biomolecules

Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease

(2019) Silvia Carvajal et al.   Scientific Reports

Spherical neutral gold nanoparticles improve anti-inflammatory response, oxidative stress and fibrosis in alcohol-methamphetamine-induced liver injury in rats

(2018) Thaís Gomes de Carvalho et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biosynthesis of cerium oxide nanoparticles and their effect on lipopolysaccharide (LPS) induced sepsis mortality and associated hepatic dysfunction in male Sprague Dawley rats

(2018) Guoqiang Chen et al.   Materials Science & Engineering C-Materials for Biological Applications

Oleuropein and hydroxytyrosol rich extracts from olive leaves attenuate liver injury and lipid metabolism disturbance in bisphenol A-treated rats

(2018) Asma Mahmoudi et al.   Food & Function

Nonalcoholic Fatty Liver Disease Cirrhosis: A Review of Its Epidemiology, Risk Factors, Clinical Presentation, Diagnosis, Management, and Prognosis

(2018) Bei Li et al.   Canadian Journal of Gastroenterology and Hepatology

Chitosan-functionalized lipid-polymer hybrid nanoparticles for oral delivery of silymarin and enhanced lipid-lowering effect in NAFLD

(2018) Jun Liang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Non-alcoholic fatty liver disease – A global public health perspective

(2018) Zobair M. Younossi   JOURNAL OF HEPATOLOGY

Resveratrol-loaded PLGA nanoparticles: enhanced stability, solubility and bioactivity of resveratrol for non-alcoholic fatty liver disease therapy

(2018) Shuqian Wan et al.   Royal Society Open Science

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Nanoparticles for the treatment of liver fibrosis

(2017) Suchithra Poilil Surendran et al.   International Journal of Nanomedicine

Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice

(2017) Rodrigo Valenzuela et al.   Lipids in Health and Disease

Modulation of electrostatic interactions to improve controlled drug delivery from nanogels

(2017) Emanuele Mauri et al.   Materials Science & Engineering C-Materials for Biological Applications

Synthesis of a novel thermo/pH sensitive nanogel based on salep modified graphene oxide for drug release

(2017) Ghasem Rezanejade Bardajee et al.   Materials Science & Engineering C-Materials for Biological Applications

Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic

(2017) Donna L Mendrick et al.   TOXICOLOGICAL SCIENCES

Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications

(2016) Anisha A. D’souza et al.   Expert Opinion on Drug Delivery

Cerium oxide nanoparticles reduce steatosis, portal hypertension and display anti-inflammatory properties in rats with liver fibrosis

(2016) Denise Oró et al.   JOURNAL OF HEPATOLOGY

Hydroxytyrosol prevents metabolic impairment reducing hepatic inflammation and restoring duodenal integrity in a rat model of NAFLD

(2016) Claudio Pirozzi et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

New progress and prospects: The application of nanogel in drug delivery

(2016) Hui Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

Comparison between two different click strategies to synthesize fluorescent nanogels for therapeutic applications

(2016) Emanuele Mauri et al.   REACTIVE & FUNCTIONAL POLYMERS

Drug-Polymer Interactions in Hydrogel-based Drug-Delivery Systems: An Experimental and Theoretical Study

(2015) Filippo Rossi et al.   CHEMPHYSCHEM

LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells

(2015) Juan Carlos García-Cañaveras et al.   ELECTROPHORESIS

Modulation of hepatic lipid metabolism by olive oil and its phenols in nonalcoholic fatty liver disease

(2015) Paola Priore et al.   IUBMB LIFE

Preparation, in vitro and in vivo evaluation of mPEG-PLGA nanoparticles co-loaded with syringopicroside and hydroxytyrosol

(2015) Qingxia Guan et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells

(2015) Úrsula Catalán et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protective Effect of the Y220C Mutant p53 Against Steatosis: Good News?

(2014) Manuele Gori et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Extra virgin olive oil phenols down-regulate lipid synthesis in primary-cultured rat-hepatocytes

(2014) Paola Priore et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Engineered nanoparticles interacting with cells: size matters

(2014) Li Shang et al.   JOURNAL OF NANOBIOTECHNOLOGY

A New Multiresponsive Drug Delivery System using Smart Nanogels

(2013) Gökçen Birlik Demirel et al.   CHEMPHYSCHEM

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

(2013) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nano-structured smart hydrogels with rapid response and high elasticity

(2013) Lie-Wen Xia et al.   Nature Communications

Review of natural products actions on cytokines in inflammatory bowel disease

(2012) Sun Jin Hur et al.   NUTRITION RESEARCH

Tunable Growth Factor Delivery from Injectable Hydrogels for Tissue Engineering

(2011) Katarina Vulic et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Nanogels in the race for drug delivery

(2010) Serguei V Vinogradov   Nanomedicine

Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes

(2009) Matteo Ricchi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The Impact of PEGylation on Biological Therapies

(2008) Francesco M Veronese et al.   BIODRUGS

Lipid-Lowering and Antioxidant Effects of Hydroxytyrosol and Its Triacetylated Derivative Recovered from Olive Tree Leaves in Cholesterol-Fed Rats

(2008) Hedya Jemai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY