Multi-omics characterization and validation of MSI-related molecular features across multiple malignancies

Prognosis and chemosensitivity of deficient MMR phenotype in patients with metastatic colorectal cancer: An AGEO retrospective multicenter study

(2020) David Tougeron et al.   INTERNATIONAL JOURNAL OF CANCER

Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy

(2020) Qiushi Li et al.   Nature Communications

Increased glycolysis correlates with elevated immune activity in tumor immune microenvironment

(2019) Zehang Jiang et al.   EBioMedicine

Cross-platform Data Analysis Reveals a Generic Gene Expression Signature for Microsatellite Instability in Colorectal Cancer

(2019) Anna Pačínková et al.   Biomed Research International

Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells

(2019) Trillian Gregg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities

(2019) Suhas Vasaikar et al.   CELL

Prognosis of microsatellite instability and/or mismatch repair deficiency stage III colon cancer patients after disease recurrence following adjuvant treatment: results of an ACCENT pooled analysis of seven studies

(2019) J Taieb et al.   ANNALS OF ONCOLOGY

Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

(2019) Carino Gurjao et al.   Cancer Immunology Research

Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects

(2019) Tamas Kiss et al.   GeroScience

Immune checkpoint inhibitors for the treatment of MSI-H/MMR-D colorectal cancer and a perspective on resistance mechanisms

(2019) Ibrahim Halil Sahin et al.   BRITISH JOURNAL OF CANCER

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

(2018) Tina Cascone et al.   Cell Metabolism

A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations

(2018) David Tamborero et al.   CLINICAL CANCER RESEARCH

Accurate Pan-Cancer Molecular Diagnosis of Microsatellite Instability by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing

(2018) Adam Waalkes et al.   CLINICAL CHEMISTRY

DNA mismatch repair in cancer

(2018) Marina Baretti et al.   PHARMACOLOGY & THERAPEUTICS

Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer

(2018) Wenji Yan et al.   Clinical Epigenetics

Analysis of DNA modifications in aging research

(2018) Dustin R. Masser et al.   GeroScience

DNA methylation associated with healthy aging of elderly twins

(2018) Sangkyu Kim et al.   GeroScience

Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade

(2018) Wassim Abida et al.   JAMA Oncology

A molecular portrait of microsatellite instability across multiple cancers

(2017) Isidro Cortes-Ciriano et al.   Nature Communications

Microsatellite instability is a biomarker for immune checkpoint inhibitors in endometrial cancer

(2017) Hitomi Yamashita et al.   Oncotarget

Checkpoint inhibitors in endometrial cancer: preclinical rationale and clinical activity

(2017) Gloria Mittica et al.   Oncotarget

LYG1 exerts antitumor function through promoting the activation, proliferation, and function of CD4+ T cells

(2017) Huihui Liu et al.   OncoImmunology

Mismatch Repair Deficiency, Microsatellite Instability, and Survival

(2017) Elizabeth C. Smyth et al.   JAMA Oncology

Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease

(2016) Solaiman Raha et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Prognostic Value ofBRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer

(2016) Julien Taieb et al.   JNCI-Journal of the National Cancer Institute

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

Classification and characterization of microsatellite instability across 18 cancer types

(2016) Ronald J Hause et al.   NATURE MEDICINE

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis

(2016) Sandra Kümper et al.   eLife

Prognostic Value ofBRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer

(2016) Julien Taieb et al.   JNCI-Journal of the National Cancer Institute

Microsatellite instability: an update

(2015) Hiroyuki Yamamoto et al.   ARCHIVES OF TOXICOLOGY

Low-Level Microsatellite Instability as a Potential Prognostic Factor in Sporadic Colorectal Cancer

(2015) Soo Young Lee et al.   MEDICINE

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK

(2015) Celia J. Vogel et al.   Pigment Cell & Melanoma Research

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Prognosis of stage II and III colon cancer treated with adjuvant 5-fluorouracil or FOLFIRI in relation to microsatellite status: results of the PETACC-3 trial

(2014) D. Klingbiel et al.   ANNALS OF ONCOLOGY

Inhibition of S6K1 enhances dichloroacetate-induced cell death

(2014) Sung-Eun Hong et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

Association Between Recurrent Metastasis From Stage II and III Primary Colorectal Tumors and Moderate Microsatellite Instability

(2012) Melissa Garcia et al.   GASTROENTEROLOGY

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Discrimination of Patients with Microsatellite Instability Colon Cancer using1H HR MAS MR Spectroscopy and Chemometric Analysis

(2010) May-Britt Tessem et al.   JOURNAL OF PROTEOME RESEARCH

Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers

(2008) Yvette Schwitalle et al.   GASTROENTEROLOGY