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Title
Inhibition of S6K1 enhances dichloroacetate-induced cell death
Authors
Keywords
Breast cancer, Dichloroacetate, Glucose metabolism, HK2, S6K1
Journal
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Volume 141, Issue 7, Pages 1171-1179
Publisher
Springer Nature
Online
2014-12-03
DOI
10.1007/s00432-014-1887-9
References
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Note: Only part of the references are listed.- Inhibition of S6K1 enhances glucose deprivation-induced cell death via downregulation of anti-apoptotic proteins in MCF-7 breast cancer cells
- (2013) Ha-Na Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2013) W Y Sanchez et al. BRITISH JOURNAL OF CANCER
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- (2013) Y Zhao et al. Cell Death & Disease
- S6K1 determines the metabolic requirements for BCR-ABL survival
- (2012) J F Barger et al. ONCOGENE
- Combination of Sulindac and Dichloroacetate Kills Cancer Cells via Oxidative Damage
- (2012) Kasirajan Ayyanathan et al. PLoS One
- Targeting cancer metabolism: a therapeutic window opens
- (2011) Matthew G. Vander Heiden NATURE REVIEWS DRUG DISCOVERY
- Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency
- (2011) P. Tandon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)
- (2010) Laura R. Pearce et al. BIOCHEMICAL JOURNAL
- Cancer metabolism: The Warburg effect today
- (2010) Leonardo M.R. Ferreira EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC
- (2010) Luke H. Stockwin et al. INTERNATIONAL JOURNAL OF CANCER
- Uncoupling the Warburg effect from cancer
- (2010) A. Najafov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic Modulation of Glioblastoma with Dichloroacetate
- (2010) E. D. Michelakis et al. Science Translational Medicine
- Medullary thyroid carcinoma relapse reversed with dichloroacetate: A case report
- (2010) DANA FLAVIN Oncology Letters
- Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
- (2009) Ramon C. Sun et al. BREAST CANCER RESEARCH AND TREATMENT
- Nuclear protein 1 induced by ATF4 in response to various stressors acts as a positive regulator on the transcriptional activation of ATF4
- (2009) Hyeon-Ok Jin et al. IUBMB LIFE
- Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
- (2008) E D Michelakis et al. BRITISH JOURNAL OF CANCER
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- Dichloroacetate (DCA) sensitizes both wild‐type and over expressingBcl‐2prostate cancer cells in vitro to radiation
- (2008) Wengang Cao et al. PROSTATE
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