Real-time fluorescence imaging in intraoperative decision making for cancer surgery

Carcinoembryonic antigen-specific, fluorescent image-guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer

(2020) D. P. Schaap et al.   BRITISH JOURNAL OF SURGERY

Intraoperative Molecular Imaging for ex vivo Assessment of Peripheral Margins in Oral Squamous Cell Carcinoma

(2020) Shayan Fakurnejad et al.   Frontiers in Oncology

First-in-Human Assessment of cRGD-ZW800-1, a Zwitterionic, Integrin-Targeted, Near-Infrared Fluorescent Peptide in Colon Carcinoma

(2020) Kim S de Valk et al.   CLINICAL CANCER RESEARCH

A study investigating the perfusion of colorectal anastomoses using fluorescence angiography: results of the FLAG randomized trial

(2020) M. Alekseev et al.   Colorectal Disease

Intraoperative fluorescence imaging with indocyanine green in hepatic resection for malignancy: a systematic review and meta-analysis of diagnostic test accuracy studies

(2020) Kieran Purich et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Visualising improved peritoneal perfusion at lower intra-abdominal pressure by fluorescent imaging during laparoscopic surgery: A randomised controlled study

(2020) Kim I. Albers et al.   International Journal of Surgery

Tumour-specific fluorescence-guided surgery for pancreatic cancer using panitumumab-IRDye800CW: a phase 1 single-centre, open-label, single-arm, dose-escalation study

(2020) Guolan Lu et al.   Lancet Gastroenterology & Hepatology

Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery

(2020) F. J. Voskuil et al.   Nature Communications

Fluorescence Imaging of Nerves During Surgery

(2019) Erika M. Walsh et al.   ANNALS OF SURGERY

Low-dose indocyanine green fluorescence-navigated segmentectomy: prospective analysis of 20 cases and review of previous reports

(2019) Nozomu Motono et al.   Journal of Thoracic Disease

Proceedings - Pathways for Successful Translation of New Imaging Agents and Modalities: Phase III Studies

(2019) Sanjiv S. Gambhir et al.   JOURNAL OF NUCLEAR MEDICINE

The Clinical Application of Fluorescence-Guided Surgery in Head and Neck Cancer

(2019) Stan van Keulen et al.   JOURNAL OF NUCLEAR MEDICINE

Relocation of inadequate resection margins in the wound bed during oral cavity oncological surgery: A feasibility study

(2019) Cornelia G.F. van Lanschot et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The Sentinel Margin: Intraoperative ex-vivo Specimen Mapping Using Relative Fluorescence Intensity

(2019) Stan van Keulen et al.   CLINICAL CANCER RESEARCH

Optimal Dosing Strategy for Fluorescence-Guided Surgery with Panitumumab-IRDye800CW in Head and Neck Cancer

(2019) Naoki Nishio et al.   MOLECULAR IMAGING AND BIOLOGY

A systematic review of the use of near-infrared fluorescence imaging in patients with peripheral artery disease

(2019) Pim van den Hoven et al.   JOURNAL OF VASCULAR SURGERY

Latest developments in molecular tracers for fluorescence image-guided cancer surgery

(2019) Sophie Hernot et al.   LANCET ONCOLOGY

A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery

(2019) Kim S. de Valk et al.   Nature Communications

Toward Quantitative Neurosurgical Guidance With High-Resolution Microscopy of 5-Aminolevulinic Acid-Induced Protoporphyrin IX

(2019) Linpeng Wei et al.   Frontiers in Oncology

Intraoperative Tumor Assessment Using Real-Time Molecular Imaging in Head and Neck Cancer Patients

(2019) Stan van Keulen et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Outcomes of DIEP flap and fluorescent angiography

(2019) Ramon Varela et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer

(2019) Naoki Nishio et al.   Nature Communications

Intraoperative near-infrared imaging with receptor-specific versus passive delivery of fluorescent agents in pituitary adenomas

(2019) Steve S. Cho et al.   JOURNAL OF NEUROSURGERY

Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence

(2018) Rebecca W. Gao et al.   CANCER RESEARCH

Setting Standards for Reporting and Quantification in Fluorescence-Guided Surgery

(2018) Charlotte Hoogstins et al.   MOLECULAR IMAGING AND BIOLOGY

Identification of a Folate Receptor-Targeted Near-Infrared Molecular Contrast Agent to Localize Pulmonary Adenocarcinomas

(2018) Jarrod D. Predina et al.   MOLECULAR THERAPY

Detecting tumour-positive resection margins after oral cancer surgery by spraying a fluorescent tracer activated by gamma-glutamyltranspeptidase

(2018) Maxime D. Slooter et al.   ORAL ONCOLOGY

Costs and effects of intra-operative fluorescence molecular imaging – A model-based, early assessment

(2018) Maximilian Präger et al.   PLoS One

Tumor-targeted Dual-modality Imaging to Improve Intraoperative Visualization of Clear Cell Renal Cell Carcinoma: A First in Man Study

(2018) Marlène C. Hekman et al.   Theranostics

Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent

(2018) Charlotte E. S. Hoogstins et al.   ANNALS OF SURGICAL ONCOLOGY

Targeted Optical Imaging Agents in Cancer: Focus on Clinical Applications

(2018) Bishnu P. Joshi et al.   Contrast Media & Molecular Imaging

Intraoperative fluorescence imaging in thoracic surgery

(2018) Andrew D. Newton et al.   JOURNAL OF SURGICAL ONCOLOGY

Fluorescence-guided surgery for liver tumors

(2018) Yuichi Nakaseko et al.   JOURNAL OF SURGICAL ONCOLOGY

Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers

(2018) Marjory Koller et al.   Nature Communications

Real-time Visualization of Breast Carcinoma in Pathology Specimens From Patients Receiving Fluorescent Tumor-Marking Agent Tozuleristide

(2018) Suzanne M. Dintzis et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

A clinical trial of intraoperative near-infrared imaging to assess tumor extent and identify residual disease during anterior mediastinal tumor resection

(2018) Jarrod D. Predina et al.   CANCER

Surgical Adjuncts to Increase the Extent of Resection

(2018) Todd Hollon et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma

(2018) Stan van Keulen et al.   ORAL ONCOLOGY

Detection of Sessile Serrated Adenomas in the Proximal Colon Using Wide-Field Fluorescence Endoscopy

(2017) Bishnu P. Joshi et al.   GASTROENTEROLOGY

Folate receptor overexpression can be visualized in real time during pituitary adenoma endoscopic transsphenoidal surgery with near-infrared imaging

(2017) John Y. K. Lee et al.   JOURNAL OF NEUROSURGERY

Intraoperative imaging of hepatic cancers using γ-glutamyltranspeptidase-specific fluorophore enabling real-time identification and estimation of recurrence

(2017) Yoichi Miyata et al.   Scientific Reports

Water Concentration Analysis by Raman Spectroscopy to Determine the Location of the Tumor Border in Oral Cancer Surgery

(2016) E. M. Barroso et al.   CANCER RESEARCH

Tumor-Specific Uptake of Fluorescent Bevacizumab–IRDye800CW Microdosing in Patients with Primary Breast Cancer: A Phase I Feasibility Study

(2016) Laetitia E. Lamberts et al.   CLINICAL CANCER RESEARCH

A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer

(2016) C. E. S. Hoogstins et al.   CLINICAL CANCER RESEARCH

Characterizing the Utility and Limitations of Repurposing an Open-Field Optical Imaging Device for Fluorescence-Guided Surgery in Head and Neck Cancer Patients

(2016) Lindsay S. Moore et al.   JOURNAL OF NUCLEAR MEDICINE

Intraoperative Molecular Diagnostic Imaging Can Identify Renal Cell Carcinoma

(2016) Thomas J. Guzzo et al.   JOURNAL OF UROLOGY

ALA-induced fluorescence image guided surgery of meningiomas: A meta-analyses

(2016) Naomi Foster et al.   Photodiagnosis and Photodynamic Therapy

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

(2016) Melodi Javid Whitley et al.   Science Translational Medicine

Laparoscopic detection and resection of occult liver tumors of multiple cancer types using real-time near-infrared fluorescence guidance

(2016) Leonora S. F. Boogerd et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES

Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor specific agent EC17

(2016) Quirijn R.J.G. Tummers et al.   Oncotarget

Resection Margin and Survival in 2368 Patients Undergoing Hepatic Resection for Metastatic Colorectal Cancer

(2015) Eran Sadot et al.   ANNALS OF SURGERY

Safety and Tumor Specificity of Cetuximab-IRDye800 for Surgical Navigation in Head and Neck Cancer

(2015) E. L. Rosenthal et al.   CLINICAL CANCER RESEARCH

Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report

(2015) E. L. Rosenthal et al.   JOURNAL OF NUCLEAR MEDICINE

Indocyanine green (ICG) fluorescence-guided laparoscopic adrenalectomy

(2015) Jonathan C. DeLong et al.   JOURNAL OF SURGICAL ONCOLOGY

Intraoperative molecular imaging can identify lung adenocarcinomas during pulmonary resection

(2015) Olugbenga T. Okusanya et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met

(2015) Jacobus Burggraaf et al.   NATURE MEDICINE

A Pilot Cost-Effectiveness Analysis of Treatments in Newly Diagnosed High-Grade Gliomas

(2015) Susana Esteves et al.   NEUROSURGERY

What is the Surgical Benefit of Utilizing 5-Aminolevulinic Acid for Fluorescence-Guided Surgery of Malignant Gliomas?

(2015) Costas G. Hadjipanayis et al.   NEUROSURGERY

The Value of Intraoperative Near-Infrared Fluorescence Imaging Based on Enhanced Permeability and Retention of Indocyanine Green: Feasibility and False-Positives in Ovarian Cancer

(2015) Quirijn R. J. G. Tummers et al.   PLoS One

Impact of 5-aminolevulinic acid fluorescence-guided surgery on the extent of resection of meningiomas – With special regard to high-grade tumors

(2014) J.F. Cornelius et al.   Photodiagnosis and Photodynamic Therapy

Optical Image-Guided Cancer Surgery: Challenges and Limitations

(2013) S. Keereweer et al.   CLINICAL CANCER RESEARCH

Image-guided cancer surgery using near-infrared fluorescence

(2013) Alexander L. Vahrmeijer et al.   Nature Reviews Clinical Oncology

Targeted Imaging of Esophageal Neoplasia with a Fluorescently Labeled Peptide: First-in-Human Results

(2013) M. B. Sturm et al.   Science Translational Medicine

In vivo molecular imaging of epidermal growth factor receptor in patients with colorectal neoplasia using confocal laser endomicroscopy

(2012) Jun Liu et al.   CANCER LETTERS

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Intraoperative indocyanine green fluorescent imaging for prevention of bile leakage after hepatic resection

(2011) Masaki Kaibori et al.   SURGERY

Real-time identification of liver cancers by using indocyanine green fluorescent imaging

(2009) Takeaki Ishizawa et al.   CANCER

Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy

(2008) Pei-Lin Hsiung et al.   NATURE MEDICINE

GLIOMA EXTENT OF RESECTION AND ITS IMPACT ON PATIENT OUTCOME

(2008) Nader Sanai et al.   NEUROSURGERY