What is the Surgical Benefit of Utilizing 5-Aminolevulinic Acid for Fluorescence-Guided Surgery of Malignant Gliomas?

Role of neurochemical navigation with 5-aminolevulinic acid during intraoperative MRI-guided resection of intracranial malignant gliomas

(2015) Shinobu Yamada et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

5-ALA Fluorescence Image Guided Resection of Glioblastoma Multiforme: A Meta-Analysis of the Literature

(2015) Samy Eljamel   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Feasibility of fluorescence-guided resection of recurrent gliomas using five-aminolevulinic acid: retrospective analysis of surgical and neurological outcome in 58 patients

(2015) Anne-Katrin Hickmann et al.   JOURNAL OF NEURO-ONCOLOGY

Predicting the “usefulness” of 5-ALA-derived tumor fluorescence for fluorescence-guided resections in pediatric brain tumors: a European survey

(2014) Walter Stummer et al.   ACTA NEUROCHIRURGICA

5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy

(2014) Marcel A. Kamp et al.   ACTA NEUROCHIRURGICA

Intraoperative visualization of brain tumors with 5-aminolevulinic acid-induced fluorescence

(2014) Georg Widhalm   CLINICAL NEUROPATHOLOGY

5-aminolevulinic acid and neuronavigation in high-grade glioma surgery: results of a combined approach

(2014) Pier Paolo Panciani et al.   NEUROCIRUGIA

Tumor detection with 5-aminolevulinic acid fluorescence and Gd-DTPA–enhanced intraoperative MRI at the border of contrast-enhancing lesions: a prospective study based on histopathological assessment

(2014) Jan Coburger et al.   Neurosurgical Focus

Intraoperative monopolar mapping during 5-ALA–guided resections of glioblastomas adjacent to motor eloquent areas: evaluation of resection rates and neurological outcome

(2014) Philippe Schucht et al.   Neurosurgical Focus

Intraoperative Fluorescence-Guided Resection of High-Grade Malignant Gliomas Using 5-Aminolevulinic Acid–Induced Porphyrins: A Systematic Review and Meta-Analysis of Prospective Studies

(2013) Shiguang Zhao et al.   PLoS One

5-Aminolevulinic Acid Induced Fluorescence Is a Powerful Intraoperative Marker for Precise Histopathological Grading of Gliomas with Non-Significant Contrast-Enhancement

(2013) Georg Widhalm et al.   PLoS One

Endoscopic-Assisted Visualization of 5-Aminolevulinic Acid–Induced Fluorescence in Malignant Glioma Surgery: A Technical Note

(2013) Marion Rapp et al.   World Neurosurgery

Increased Expression of ABCB6 Enhances Protoporphyrin IX Accumulation and Photodynamic Effect in Human Glioma

(2012) Shi-Guang Zhao et al.   ANNALS OF SURGICAL ONCOLOGY

Quantitative volumetric analysis of gliomas with sequential MRI and 11C-methionine PET assessment: patterns of integration in therapy planning

(2012) Javier Arbizu et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Intraoperative tissue fluorescence using 5-aminolevolinic acid (5-ALA) is more sensitive than contrast MRI or amino acid positron emission tomography (18F-FET PET) in glioblastoma surgery

(2012) Karl Roessler et al.   NEUROLOGICAL RESEARCH

Finding the anaplastic focus in diffuse gliomas: The value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence

(2011) Christian Ewelt et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Fluorescence and image guided resection in high grade glioma

(2011) Pier Paolo Panciani et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery

(2011) Pablo A. Valdés et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker

(2011) Pablo A. Valdés et al.   JOURNAL OF NEUROSURGERY

Intraoperative confocal microscopy in the visualization of 5-aminolevulinic acid fluorescence in low-grade gliomas

(2011) Nader Sanai et al.   JOURNAL OF NEUROSURGERY

Hot spots in dynamic18FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas

(2011) M. Kunz et al.   NEURO-ONCOLOGY

Pathological characterization of the glioblastoma border as shown during surgery using 5-aminolevulinic acid-induced fluorescence

(2011) Miguel Angel Idoate et al.   NEUROPATHOLOGY

Precise comparison of protoporphyrin IX fluorescence spectra with pathological results for brain tumor tissue identification

(2010) Takehiro Ando et al.   Brain Tumor Pathology

5-Aminolevulinic acid is a promising marker for detection of anaplastic foci in diffusely infiltrating gliomas with nonsignificant contrast enhancement

(2010) Georg Widhalm et al.   CANCER

Surgery guided by 5-aminolevulinic fluorescence in glioblastoma: volumetric analysis of extent of resection in single-center experience

(2010) Ricardo Díez Valle et al.   JOURNAL OF NEURO-ONCOLOGY

Counterbalancing risks and gains from extended resections in malignant glioma surgery: a supplemental analysis from the randomized 5-aminolevulinic acid glioma resection study

(2010) Walter Stummer et al.   JOURNAL OF NEUROSURGERY

Coregistered fluorescence-enhanced tumor resection of malignant glioma: relationships between δ-aminolevulinic acid–induced protoporphyrin IX fluorescence, magnetic resonance imaging enhancement, and neuropathological parameters

(2010) David W. Roberts et al.   JOURNAL OF NEUROSURGERY

Independent association of extent of resection with survival in patients with malignant brain astrocytoma

(2008) Matthew J. McGirt et al.   JOURNAL OF NEUROSURGERY