Dysregulation of Principal Cell miRNAs Facilitates Epigenetic Regulation of AQP2 and Results in Nephrogenic Diabetes Insipidus

RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus

(2019) Chih-Chien Sung et al.   KIDNEY INTERNATIONAL

Transcription Factor Elf3 Modulates Vasopressin-Induced Aquaporin-2 Gene Expression in Kidney Collecting Duct Cells

(2019) Shu-Ting Lin et al.   Frontiers in Physiology

Genome-Wide Mapping of DNA Accessibility and Binding Sites for CREB and C/EBPβin Vasopressin-Sensitive Collecting Duct Cells

(2018) Hyun Jun Jung et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice

(2018) Anna Iervolino et al.   Frontiers in Physiology

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance

(2017) Erfan Aref-Eshghi et al.   Epigenetics

Lithium increases ammonium excretion leading to altered urinary acid-base buffer composition

(2017) Francesco Trepiccione et al.   JOURNAL OF NEPHROLOGY

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis

(2017) Sachin Hajarnis et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Systems-level identification of PKA-dependent signaling in epithelial cells

(2017) Kiyoshi Isobe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reciprocal regulation between microRNAs and epigenetic machinery in colorectal cancer

(2017) Feng Wang et al.   Oncology Letters

Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons

(2017) Marilyn Scandaglia et al.   Cell Reports

Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure

(2016) Malte P. Bartram et al.   BMC MOLECULAR BIOLOGY

Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System

(2016) F. Trepiccione et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Double Knockout of the Na+-Driven Cl−/HCO3−Exchanger and Na+/Cl−Cotransporter Induces Hypokalemia and Volume Depletion

(2016) Anne Sinning et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells

(2016) Tiziana Angrisano et al.   PLoS One

Application of small RNA sequencing to identify microRNAs in acute kidney injury and fibrosis

(2016) Kathryn L. Pellegrini et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy

(2016) Shawn S. Badal et al.   Nature Communications

Systems-level analysis reveals selective regulation of Aqp2 gene expression by vasopressin

(2016) Pablo C. Sandoval et al.   Scientific Reports

Relative Roles of Principal and Intercalated Cells in the Regulation of Sodium Balance and Blood Pressure

(2015) Régine Chambrey et al.   CURRENT HYPERTENSION REPORTS

Regulation of the Water Channel Aquaporin-2 via 14-3-3θ and -ζ

(2015) Hanne B. Moeller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Dicer Suppression in the Kidney Alters GSK3β/β-Catenin Pathways Promoting a Glomerulocystic Disease

(2015) Anna Iervolino et al.   PLoS One

DNA methylation is required for the control of stem cell differentiation in the small intestine

(2014) K. L. Sheaffer et al.   GENES & DEVELOPMENT

MicroRNA-29a Promotion of Nephrin Acetylation Ameliorates Hyperglycemia-Induced Podocyte Dysfunction

(2014) C.-L. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Early targets of lithium in rat kidney inner medullary collecting duct include p38 and ERK1/2

(2014) Francesco Trepiccione et al.   KIDNEY INTERNATIONAL

GATA2 Regulates Body Water Homeostasis through Maintaining Aquaporin 2 Expression in Renal Collecting Ducts

(2014) L. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Renal β-intercalated cells maintain body fluid and electrolyte balance

(2013) Victor Gueutin et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative Proteomics Identifies Vasopressin-Responsive Nuclear Proteins in Collecting Duct Cells

(2012) L. K. Schenk et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cell biology of vasopressin-regulated aquaporin-2 trafficking

(2012) Hanne B. Moeller et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

PKA-dependent regulation of the histone lysine demethylase complex PHF2–ARID5B

(2011) Atsushi Baba et al.   NATURE CELL BIOLOGY

MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics

(2011) Lily Ting et al.   NATURE METHODS

Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

(2010) Weifeng Huang et al.   NUCLEIC ACIDS RESEARCH

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice

(2009) Hyun-Woo Jeong et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract

(2009) Laura M. Pastorelli et al.   MAMMALIAN GENOME

Revisiting the principles of microRNA target recognition and mode of action

(2009) Peter Brodersen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions

(2009) H. B. Moeller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct

(2009) M.-J. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute regulation of aquaporin-2 phosphorylation at Ser-264 by vasopressin

(2008) R. A. Fenton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA