Downregulation of fatty acid oxidation by involvement of HIF-1α and PPARγ in human gastric adenocarcinoma and related clinical significance

PPARG Drives Molecular Networks as an Inhibitor for the Pathologic Development and Progression of Lung Adenocarcinoma

(2020) Min Zhao et al.   PPAR Research

Aberrant lipid metabolism as a therapeutic target in liver cancer

(2019) Evans D. Pope et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinoma

(2019) Rana Ezzeddini et al.   LIFE SCIENCES

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

(2018) Tina Cascone et al.   Cell Metabolism

Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling

(2018) Bianca C. Bernardo et al.   CLINICAL SCIENCE

Suppression of mitochondrial oxygen metabolism mediated by the transcription factor HIF-1 alleviates propofol-induced cell toxicity

(2018) Chisato Sumi et al.   Scientific Reports

Submucosal fat accumulation in human colorectal tissue and its association with abdominal obesity and insulin resistance

(2018) Seriko Wada et al.   United European Gastroenterology Journal

Fatty acid oxidation is associated with proliferation and prognosis in breast and other cancers

(2018) Aziz Aiderus et al.   BMC CANCER

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Fatty acid oxidation: An emerging facet of metabolic transformation in cancer

(2018) Yibao Ma et al.   CANCER LETTERS

Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic syndrome

(2017) Chek Kun Tan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Pioglitazone inhibits cancer cell growth through STAT3 inhibition and enhanced AIF expression via a PPARγ-independent pathway

(2017) Masanobu Tsubaki et al.   JOURNAL OF CELLULAR PHYSIOLOGY

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Intracellular mechanisms underlying lipid accumulation (white opaque substance) in gastric epithelial neoplasms: A pilot study of expression profiles of lipid-metabolism-associated genes

(2016) Munechika Enjoji et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Cinnamon extract reduces VEGF expression via suppressing HIF-1α gene expression and inhibits tumor growth in mice

(2016) Keqiang Zhang et al.   MOLECULAR CARCINOGENESIS

Diet-induced alteration of fatty acid synthase in prostate cancer progression

(2016) M Huang et al.   Oncogenesis

Hypoxia and hypoxia inducible factors in tumor metabolism

(2015) Wen Zeng et al.   CANCER LETTERS

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

(2015) C A Lewis et al.   ONCOGENE

Novel Pathway for Hypoxia-Induced Proliferation and Migration in Human Mesenchymal Stem Cells: Involvement of HIF-1α, FASN, and mTORC1

(2015) Hyun Jik Lee et al.   STEM CELLS

Mitochondrial oncobioenergetic index: A potential biomarker to predict progression from indolent to aggressive prostate cancer

(2015) Praveen K. Vayalil et al.   Oncotarget

Inhibition of Cancer Cell Proliferation by PPARγ Is Mediated by a Metabolic Switch that Increases Reactive Oxygen Species Levels

(2014) Nishi Srivastava et al.   Cell Metabolism

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation

(2014) Yanlong Liu et al.   TOXICOLOGY LETTERS

HIF-1-Mediated Suppression of Acyl-CoA Dehydrogenases and Fatty Acid Oxidation Is Critical for Cancer Progression

(2014) De Huang et al.   Cell Reports

Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation

(2014) Karim Bensaad et al.   Cell Reports

Cancer as a metabolic disease: implications for novel therapeutics

(2013) T. N. Seyfried et al.   CARCINOGENESIS

Hypoxia downregulates PPARγ via an ERK1/2–NF-κB–Nox4-dependent mechanism in human pulmonary artery smooth muscle cells

(2013) Xianghuai Lu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The expression of C-FABP and PPARγ and their prognostic significance in prostate cancer

(2013) FARZAD S. FOROOTAN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Peroxisome proliferator-activated receptors and cancer: challenges and opportunities

(2011) Jihan Youssef et al.   BRITISH JOURNAL OF PHARMACOLOGY

Intramyocellular lipid droplets increase with progression of cachexia in cancer patients

(2011) Nathan A. Stephens et al.   Journal of Cachexia Sarcopenia and Muscle

Rosiglitazone Attenuates Chronic Hypoxia–Induced Pulmonary Hypertension in a Mouse Model

(2009) Rachel E. Nisbet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cancer incidence and mortality in Iran

(2008) S. M. Mousavi et al.   ANNALS OF ONCOLOGY

Colorectal Cancer Expression of Peroxisome Proliferator-Activated Receptor γ (PPARG, PPARgamma) Is Associated With Good Prognosis

(2008) Shuji Ogino et al.   GASTROENTEROLOGY