Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors

Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors

(2020) Susanna Pucci et al.   PHARMACOLOGICAL RESEARCH

Conotoxins: Chemistry and Biology

(2019) Ai-Hua Jin et al.   CHEMICAL REVIEWS

Species specificity of rat and human α7 nicotinic acetylcholine receptors towards different classes of peptide and protein antagonists

(2018) Jinpeng Yu et al.   NEUROPHARMACOLOGY

Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors

(2018) Arik J. Hone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural principles of distinct assemblies of the human α4β2 nicotinic receptor

(2018) Richard M. Walsh et al.   NATURE

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors

(2017) Yong Wu et al.   JOURNAL OF MEDICINAL CHEMISTRY

αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype

(2017) Dongting Zhangsun et al.   NEUROPHARMACOLOGY

The Therapeutic Potential of α7 Nicotinic Acetylcholine Receptor (α7 nAChR) Agonists for the Treatment of the Cognitive Deficits Associated with Schizophrenia

(2015) Corinne Beinat et al.   CNS DRUGS

Long-Time-Step Molecular Dynamics through Hydrogen Mass Repartitioning

(2015) Chad W. Hopkins et al.   Journal of Chemical Theory and Computation

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors

(2014) Sulan Luo et al.   FASEB JOURNAL

Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors

(2013) Marco C. Inserra et al.   BIOCHEMICAL PHARMACOLOGY

Characterization of a Novel α-Conotoxin TxID from Conus textile That Potently Blocks Rat α3β4 Nicotinic Acetylcholine Receptors

(2013) Sulan Luo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of a Novel α-Conotoxin fromConus textileThat Selectively Targets α6/α3β2β3 Nicotinic Acetylcholine Receptors

(2012) Sulan Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined α7 nicotinic acetylcholine receptor agonism and partial serotonin transporter inhibition produce antidepressant-like effects in the mouse forced swim and tail suspension tests: A comparison of SSR180711 and PNU-282987

(2011) Jesper T. Andreasen et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Characterization of [3H]CHIBA-1001 binding to α7 nicotinic acetylcholine receptors in the brain from rat, monkey, and human

(2010) Yuko Tanibuchi et al.   BRAIN RESEARCH

α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6β4 and α6β2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release

(2010) Layla Azam et al.   FASEB JOURNAL

Characterization of a novel  4/4-conotoxin, Qc1.2, from vermivorous Conus quercinus

(2009) C. Peng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Establishing regiocontrol of disulfide bond isomers of α-conotoxin ImI via the synthesis of N-to-C cyclic analogs

(2009) Christopher J. Armishaw et al.   BIOPOLYMERS

Inhibition of Neuronal Nicotinic Acetylcholine Receptor Subtypes by α-Conotoxin GID and Analogues

(2008) Emma L. Millard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY