MECHANISMS IN ENDOCRINOLOGY: Skeletal muscle lipotoxicity in insulin resistance and type 2 diabetes: a causal mechanism or an innocent bystander?

Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans

(2016) Anne Gemmink et al.   DIABETOLOGIA

Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues

(2016) Vanessa Pellegrinelli et al.   DIABETOLOGIA

Maternal obesity epigenetically alters visceral fat progenitor cell properties in male offspring mice

(2016) Xingwei Liang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus

(2015) Raziel Rojas-Rodriguez et al.   DIABETOLOGIA

Increased fat cell size: a major phenotype of subcutaneous white adipose tissue in non-obese individuals with type 2 diabetes

(2015) Juan R. Acosta et al.   DIABETOLOGIA

Lipid-mediated muscle insulin resistance: different fat, different pathways?

(2015) Olesja Ritter et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Fatty Acids, Obesity and Insulin Resistance

(2015) Peter Arner et al.   Obesity Facts

Impaired Adipose Tissue Expandability and Lipogenic Capacities as Ones of the Main Causes of Metabolic Disorders

(2015) Isabel Moreno-Indias et al.   Journal of Diabetes Research

The cell size and distribution of adipocytes from subcutaneous and visceral fat is associated with type 2 diabetes mellitus in humans

(2015) Lingling Fang et al.   Adipocyte

Adipose tissue and its role in organ crosstalk

(2014) T. Romacho et al.   Acta Physiologica

The effect of a single 2 h bout of aerobic exercise on ectopic lipids in skeletal muscle, liver and the myocardium

(2014) Julie Bucher et al.   DIABETOLOGIA

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

(2014) Julia Szendroedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms Underlying the Onset of Oral Lipid-Induced Skeletal Muscle Insulin Resistance in Humans

(2013) B. Nowotny et al.   DIABETES

Impaired Leptin Gene Expression and Release in Cultured Preadipocytes Isolated From Individuals Born With Low Birth Weight

(2013) N. S. Schultz et al.   DIABETES

Adipose tissue and adipocyte dysregulation

(2013) M. Lafontan   DIABETES & METABOLISM

Visceral Fat Accumulation During Lipid Overfeeding Is Related to Subcutaneous Adipose Tissue Characteristics in Healthy Men

(2013) Maud Alligier et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity

(2013) P.M. Coen et al.   Obesity

Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet

(2012) Erin J. Stephenson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipogenesis: From Stem Cell to Adipocyte

(2012) Qi Qun Tang et al.   Annual Review of Biochemistry

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes

(2012) D Ferland-McCollough et al.   CELL DEATH AND DIFFERENTIATION

Abundance of Circulating Preadipocyte Factor 1 in Early Life

(2012) F. de Zegher et al.   DIABETES CARE

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans

(2012) B. C. Bergman et al.   DIABETOLOGIA

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

The epidemiology, pathogenesis and histopathology of fatty liver disease

(2012) Adam P Levene et al.   HISTOPATHOLOGY

The Triglyceride Content in Skeletal Muscle Is Associated with Hepatic But Not Peripheral Insulin Resistance in Elderly Twins

(2012) Louise Groth Grunnet et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

(2012) Atsuhiko Ichimura et al.   NATURE

The Size of Large Adipose Cells Is a Predictor of Insulin Resistance in First-Degree Relatives of Type 2 Diabetic Patients

(2012) Jian Yang et al.   Obesity

Effects of high-fat overfeeding on mitochondrial function, glucose and fat metabolism, and adipokine levels in low-birth-weight subjects

(2011) Charlotte Brøns et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation

(2011) F. Karpe et al.   DIABETES

Disassociation of Liver and Muscle Insulin Resistance from Ectopic Lipid Accumulation in Low-Birth-Weight Individuals

(2011) Sylvie Dufour et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differential Nongenetic Impact of Birth WeightVersusThird-Trimester Growth Velocity on Glucose Metabolism and Magnetic Resonance Imaging Abdominal Obesity in Young Healthy Twins

(2011) Kasper Pilgaard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Three Weeks on a High-Fat Diet Increases Intrahepatic Lipid Accumulation and Decreases Metabolic Flexibility in Healthy Overweight Men

(2011) Noud A. van Herpen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Lipodystrophies: Genetic and Acquired Body Fat Disorders

(2011) Abhimanyu Garg   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Long- and Medium-Chain Fatty Acids Induce Insulin Resistance to a Similar Extent in Humans Despite Marked Differences in Muscle Fat Accumulation

(2011) Joris Hoeks et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Dynamics of human adipose lipid turnover in health and metabolic disease

(2011) Peter Arner et al.   NATURE

Deoxyribonucleic Acid Methylation and Gene Expression ofPPARGC1Ain Human Muscle Is Influenced by High-Fat Overfeeding in a Birth-Weight-Dependent Manner

(2010) Charlotte Brøns et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The origin of intermuscular adipose tissue and its pathophysiological implications

(2009) Roberto Vettor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Intramuscular triacylglycerol and insulin resistance: Guilty as charged or wrongly accused?

(2009) Deborah M. Muoio   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lower Total Adipocyte Number but No Evidence for Small Adipocyte Depletion in Patients With Type 2 Diabetes

(2009) M. Pasarica et al.   DIABETES CARE

Intermuscular adipose tissue (IMAT): Association with other adipose tissue compartments and insulin sensitivity

(2009) Michael Boettcher et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men

(2009) Charlotte Brøns et al.   JOURNAL OF PHYSIOLOGY-LONDON

Metabolic flexibility and insulin resistance

(2008) Jose E. Galgani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

(2008) John J. Dubé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Perfect Storm: Obesity, Adipocyte Dysfunction, and Metabolic Consequences

(2008) S. de Ferranti et al.   CLINICAL CHEMISTRY

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE