SKP2-Promoted Ubiquitination of FOXO3 Promotes the Development of Asthma

LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung

(2019) Akiko Mammoto et al.   Aging-US

Fbxw7 and Skp2 Regulate Stem Cell Switch between Quiescence and Mitotic Division in Lung Adenocarcinoma

(2019) Wenzhu Zhang et al.   Biomed Research International

Glucocorticoids inhibits the repair of airway epithelial cells via the activation of wnt pathway

(2019) Zhongcui Yu et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Tanshinol alleviates impaired bone formation by inhibiting adipogenesis via KLF15/PPARγ2 signaling in GIO rats

(2018) Ya-jun Yang et al.   ACTA PHARMACOLOGICA SINICA

Interleukin-37 alleviates airway inflammation and remodeling in asthma via inhibiting the activation of NF-κB and STAT3 signalings

(2018) Nina Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells

(2018) Serena Di Vincenzo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension

(2018) Jing Jiang et al.   International Journal of Chronic Obstructive Pulmonary Disease

Effects of Aspergillus fumigatus on glucocorticoid receptor and β2-adrenergic receptor expression in a rat model of asthma

(2017) Xia Zhou et al.   EXPERIMENTAL LUNG RESEARCH

Personalized medicine with biologics for severe type 2 asthma: current status and future prospects

(2017) Marie Godar et al.   mAbs

Lrp5/β-catenin Signaling Controls Lung Macrophage Differentiation and Inhibits Resolution of Fibrosis

(2016) Joseph A Sennello et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Activation of AMPK α2 inhibits airway smooth muscle cells proliferation

(2016) Lu Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Roxithromycin inhibits VEGF-induced human airway smooth muscle cell proliferation: Opportunities for the treatment of asthma

(2016) Qing-Mei Pei et al.   EXPERIMENTAL CELL RESEARCH

Serotonin 5-HT2 receptor activation prevents allergic asthma in a mouse model

(2015) Felix Nau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Peptide Level Immunoaffinity Enrichment Enhances Ubiquitination Site Identification on Individual Proteins

(2013) Veronica G. Anania et al.   MOLECULAR & CELLULAR PROTEOMICS

Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A

(2012) Shyamala Ganesan et al.   THORAX

Expression Profiling IdentifiesKlf15as a Glucocorticoid Target That Regulates Airway Hyperresponsiveness

(2011) Kiriko Masuno et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

FOXO3 Deficiency Leads to Increased Susceptibility to Cigarette Smoke-Induced Inflammation, Airspace Enlargement, and Chronic Obstructive Pulmonary Disease

(2011) J.-w. Hwang et al.   JOURNAL OF IMMUNOLOGY

Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation

(2011) F Wang et al.   ONCOGENE

Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis

(2011) Guocan Wang et al.   Chinese Journal of Cancer

Sp1 and KLF15 regulate basal transcription of the human LRP5 gene

(2010) Jiangxia Li et al.   BMC GENETICS

Inhibition of FOXO3 Tumor Suppressor Function by βTrCP1 through Ubiquitin-Mediated Degradation in a Tumor Mouse Model

(2010) Wen-Bin Tsai et al.   PLoS One

The Expression and Prognosis of FOXO3a and Skp2 in Human Hepatocellular Carcinoma

(2009) Mudan Lu et al.   PATHOLOGY & ONCOLOGY RESEARCH