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(2020) Wenting Cheng et al.   ARCHIVES OF TOXICOLOGY

SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity

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NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegaly

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Diesel exhaust extract exposure induces neuronal toxicity by disrupting autophagy

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Real-Ambient Particulate Matter Exposure-Induced Cardiotoxicity in C57/B6 Mice

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NRF2 and Primary Cilia: An Emerging Partnership

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Caloric restriction attenuates C57BL/6 J mouse lung injury and extra-pulmonary toxicity induced by real ambient particulate matter exposure

(2020) Daochuan Li et al.   Particle and Fibre Toxicology

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Real-ambient exposure to air pollution exaggerates excessive growth of adipose tissue modulated by Nrf2 signal

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CaMKII oxidation regulates cockroach allergen–induced mitophagy in asthma

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Mitoquinone attenuates vascular calcification by suppressing oxidative stress and reducing apoptosis of vascular smooth muscle cells via the Keap1/Nrf2 pathway

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The association between ambient air pollution and blood lipids: A longitudinal study in Shijiazhuang, China

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Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo

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(2019) The Lancet   LANCET

Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy

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Autophagy is required for lung development and morphogenesis

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Nrf2 protects against diverse PM2.5 components-induced mitochondrial oxidative damage in lung cells

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Association Between Long-term Exposure to Ambient Air Pollution and Change in Quantitatively Assessed Emphysema and Lung Function

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Air pollution is linked to infant deaths and reduced lung function in children

(2019) Jacqui Wise   BMJ-British Medical Journal

Akt1 and Akt2 Isoforms Play Distinct Roles in Regulating the Development of Inflammation and Fibrosis Associated with Alcoholic Liver Disease

(2019) Karina Reyes-Gordillo et al.   Cells

Short-term PM2.5 exposure induces sustained pulmonary fibrosis development during post-exposure period in rats

(2019) Baiyang Sun et al.   JOURNAL OF HAZARDOUS MATERIALS

Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

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(2018) Philip J Landrigan et al.   LANCET

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

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TRIM16 controls assembly and degradation of protein aggregates by modulating the p62‐NRF2 axis and autophagy

(2018) Kautilya Kumar Jena et al.   EMBO JOURNAL

Age-Specific Associations of Ozone and PM2.5 with Respiratory Emergency Department Visits in the US

(2018) Heather M Strosnider et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cigarette smoke induces ROS mediated autophagy impairment in human corneal epithelial cells

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p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation

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Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

(2016) Jun Wei et al.   NATURE IMMUNOLOGY

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

(2015) Jaime L. Schneider et al.   AGING CELL

Air Pollution from Road Traffic and Systemic Inflammation in Adults: A Cross-Sectional Analysis in the European ESCAPE Project

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Long-term Exposure to Particulate Matter Constituents and the Incidence of Coronary Events in 11 European Cohorts

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Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway

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(2014) Rong Zhang et al.   Particle and Fibre Toxicology

Pulmonary and Cardiovascular Responses of Rats to Inhalation of Silver Nanoparticles

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Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

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PM2.5-bound oxygenated PAHs, nitro-PAHs and parent-PAHs from the atmosphere of a Chinese megacity: Seasonal variation, sources and cancer risk assessment

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Impaired autophagy leads to abnormal dendritic cell–epithelial cell interactions

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The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

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NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease

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Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

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p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibronectin Is an Important Regulator of Flow-Induced Vascular Remodeling

(2009) Hou-Yu Chiang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

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