Protein unbound pharmacokinetics of ambroxol in the blood and brains of rats and the interaction of ambroxol with Polygala tenuifolia by multiple microdialysis

Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations

(2020) Stephen Mullin et al.   JAMA Neurology

The onjisaponin B metabolite tenuifolin ameliorates dopaminergic neurodegeneration in a mouse model of Parkinson’s disease

(2020) Fang Peng et al.   NEUROREPORT

Ambroxol as a novel disease-modifying treatment for Parkinson’s disease dementia: protocol for a single-centre, randomized, double-blind, placebo-controlled trial

(2019) C. R. A. Silveira et al.   BMC Neurology

Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption

(2019) YinYing Ba et al.   Evidence-based Complementary and Alternative Medicine

ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches

(2019) Kevin Leandro et al.   PHARMACOLOGICAL RESEARCH

Glucocerebrosidase and its relevance to Parkinson disease

(2019) Jenny Do et al.   Molecular Neurodegeneration

Glucocerebrosidase and Parkinson Disease: Molecular, Clinical, and Therapeutic Implications

(2018) Roberta Balestrino et al.   NEUROSCIENTIST

Glucocerebrosidase mutations and synucleinopathies: Toward a model of precision medicine

(2018) Fabio Blandini et al.   MOVEMENT DISORDERS

Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice

(2016) Anna Migdalska-Richards et al.   ANNALS OF NEUROLOGY

Simultaneous determination of ambroxol and salbutamol in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study

(2016) Zhening Guo et al.   BIOMEDICAL CHROMATOGRAPHY

Tenuifolin, a saponin derived from Radix Polygalae, exhibits sleep-enhancing effects in mice

(2016) Qing Cao et al.   PHYTOMEDICINE

Ambroxol chaperone therapy for neuronopathic Gaucher disease: A pilot study

(2016) Aya Narita et al.   Annals of Clinical and Translational Neurology

Exploring the Mechanism of Salt-Induced Signal Suppression in Protein Electrospray Mass Spectrometry Using Experiments and Molecular Dynamics Simulations

(2015) Haidy Metwally et al.   ANALYTICAL CHEMISTRY

Biological Matrix Effects in Quantitative Tandem Mass Spectrometry-Based Analytical Methods: Advancing Biomonitoring

(2015) Parinya Panuwet et al.   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY

The antidepressant-like pharmacological profile of Yuanzhi-1, a novel serotonin, norepinephrine and dopamine reuptake inhibitor

(2015) Zeng-liang Jin et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Prescription patterns of Chinese herbal products for patients with sleep disorder and major depressive disorder in Taiwan

(2015) Yi-Lin Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Determination of protein-unbound rhynchiphylline brain distribution by microdialysis and ultra-performance liquid chromatography with tandem mass spectrometry

(2014) Chia-Jung Lee et al.   BIOMEDICAL CHROMATOGRAPHY

Preclinical Safety of the Root Extract ofPolygala tenuifoliaWilldenow in Sprague-Dawley Rats and Beagle Dogs

(2014) Ki Young Shin et al.   Evidence-based Complementary and Alternative Medicine

Quantitative analysis of tenuifolin concentrations in rat plasma and tissue using LC⬜MS/MS: Application to pharmacokinetic and tissue distribution study

(2013) Bo Ma et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Utility of CSF in translational neuroscience

(2013) Elizabeth C. M. de Lange   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

A sensitive LC-MS/MS method for the simultaneous determination of amoxicillin and ambroxol in human plasma with segmental monitoring

(2012) Xin Dong et al.   BIOMEDICAL CHROMATOGRAPHY

Cytochrome P450 Inactivation by Pharmaceuticals and Phytochemicals: Therapeutic Relevance

(2008) William W. Johnson   DRUG METABOLISM REVIEWS

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL