Reduning injection and its effective constituent luteoloside protect against sepsis partly via inhibition of HMGB1/TLR4/NF-κB/MAPKs signaling pathways

Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)

(2020) Li Runfeng et al.   PHARMACOLOGICAL RESEARCH

Serum and urine metabolomics based on UPLC-Q-TOF/MS reveals the antipyretic mechanism of Reduning injection in a rat model

(2019) Xia Gao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Luteoloside Protects the Uterus from Staphylococcus aureus-Induced Inflammation, Apoptosis, and Injury

(2018) Xiaoyan Wang et al.   INFLAMMATION

Anti-sepsis protection of Xuebijing injection is mediated by differential regulation of pro- and anti-inflammatory Th17 and T regulatory cells in a murine model of polymicrobial sepsis

(2018) Xi Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II

(2018) Zhongbin Zhang et al.   Journal of Neuroinflammation

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

Butein induction of HO-1 by p38 MAPK/Nrf2 pathway in adipocytes attenuates high-fat diet induced adipose hypertrophy in mice

(2017) Zheng Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Luteoloside prevents lipopolysaccharide-induced osteolysis and suppresses RANKL-induced osteoclastogenesis through attenuating RANKL signaling cascades

(2017) Fangming Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury

(2017) Xiangrong Chen et al.   Journal of Neuroinflammation

LC-MS/MS analysis and evaluation of the anti-inflammatory activity of components from BushenHuoxue decoction

(2017) Dongdong Sun et al.   PHARMACEUTICAL BIOLOGY

Identification of pharmacological agents that induce HMGB1 release

(2017) Peng Liu et al.   Scientific Reports

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response

(2017) Yung-Li Hung et al.   Scientific Reports

Procalcitonin and C-reactive protein in early diagnosis of sepsis caused by either Gram-negative or Gram-positive bacteria

(2016) H. H. Liu et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Permissive role of AMPK and autophagy in adiponectin deficiency-accentuated myocardial injury and inflammation in endotoxemia

(2016) Jun Ren et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Luteoloside Acts as 3C Protease Inhibitor of Enterovirus 71 In Vitro

(2016) Zeyu Cao et al.   PLoS One

Methylene Blue Facilitates Memory Retention in Zebrafish in a Dose-Dependent Manner

(2016) David J. Echevarria et al.   Zebrafish

Sepsis: pathophysiology and clinical management

(2016) Jeffrey E Gotts et al.   BMJ-British Medical Journal

Sepsis: pathophysiology and clinical management

(2016) Jeffrey E Gotts et al.   BMJ-British Medical Journal

Helicobacter pylori Activates HMGB1 Expression and Recruits RAGE into Lipid Rafts to Promote Inflammation in Gastric Epithelial Cells

(2016) Hwai-Jeng Lin et al.   Frontiers in Immunology

Cystine improves survival rates in a LPS-induced sepsis mouse model

(2015) Kenji A.K. Tanaka et al.   CLINICAL NUTRITION

Isolation of Luteolin and Luteolin-7-O-glucoside from Dendranthema morifolium Ramat Tzvel and Their Pharmacokinetics in Rats

(2015) Lie-Chwen Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Heme oxygenase 1-mediated novel anti-inflammatory activities of Salvia plebeia and its active components

(2015) Muhammad Akram et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data

(2015) Jie Ma et al.   MEDIATORS OF INFLAMMATION

Anti-inflammatory effects of Reduning Injection (热毒宁注射液) on lipopolysaccharide-induced acute lung injury of rats

(2014) Lu-ping Tang et al.   Chinese Journal of Integrative Medicine

Comparison between white blood cell count, procalcitonin and C reactive protein as diagnostic and prognostic biomarkers of infection or sepsis in patients presenting to emergency department

(2014) Laura Magrini et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Inhibition of adipocyte inflammation and macrophage chemotaxis by butein

(2014) Zheng Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Screening and Identification of Multi-Components in Re Du Ning Injections Using LC/TOF-MS Coupled with UV-Irradiation

(2014) Lingzhi Li et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Different Doses of Recombinant Tissue-Type Plasminogen Activator for Acute Stroke in Chinese Patients

(2014) A-Ching Chao et al.   STROKE

The Therapeutic Potential and Mechanisms of Action of Quercetin in Relation to Lipopolysaccharide-Induced Sepsis In Vitro and In Vivo

(2013) Yu-Cheng Chang et al.   PLoS One

Host innate immune responses to sepsis

(2013) Willem Joost Wiersinga et al.   Virulence

Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb. leaves

(2012) Jianhua Xiong et al.   FOOD CHEMISTRY

Oxidative stress and mitochondrial dysfunction in sepsis

(2011) H.F. Galley   BRITISH JOURNAL OF ANAESTHESIA

Multiplex cytokine profiling in patients with sepsis

(2010) SIMONA MERA et al.   APMIS

Targeting HMGB1 in inflammation

(2009) Huan Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms