Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury

Isoliquiritigenin inhibits TNF-α-induced release of high-mobility group box 1 through activation of HDAC in human intestinal epithelial HT-29 cells

(2017) Jin-Hua Chi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

(2017) Sarah Hopp et al.   Journal of Neuroinflammation

Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury

(2017) Alok Kumar et al.   Journal of Neuroinflammation

Resuscitation with Pooled and Pathogen-Reduced Plasma Attenuates the Increase in Brain Water Content following Traumatic Brain Injury and Hemorrhagic Shock in Rats

(2017) Gustav Folmer Genét et al.   JOURNAL OF NEUROTRAUMA

Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats

(2017) Dengli Wang et al.   Scientific Reports

Macrophage migration inhibitory factor promotes breast cancer metastasis via activation of HMGB1/TLR4/NF kappa B axis

(2016) Wei Lv et al.   CANCER LETTERS

High-mobility group box 1 is an important mediator of microglial activation induced by cortical spreading depression

(2016) Tsubasa Takizawa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation

(2016) Frances Corrigan et al.   Journal of Neuroinflammation

Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells

(2016) Marie-Eve Tremblay et al.   Journal of Neuroinflammation

Maternal Omega-3 Supplement Improves Dopaminergic System in Pre- and Postnatal Inflammation-Induced Neurotoxicity in Parkinson’s Disease Model

(2016) Ana Marcia Delattre et al.   MOLECULAR NEUROBIOLOGY

Enriched Endogenous Omega-3 Fatty Acids in Mice Ameliorate Parenchymal Cell Death After Traumatic Brain Injury

(2016) Huixia Ren et al.   MOLECULAR NEUROBIOLOGY

A core viral protein binds host nucleosomes to sequester immune danger signals

(2016) Daphne C. Avgousti et al.   NATURE

Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats

(2016) Xiang-Sheng Zhang et al.   Cell Death & Disease

Regnase-1 in microglia negatively regulates high mobility group box 1-mediated inflammation and neuronal injury

(2016) Xiao-Xi Liu et al.   Scientific Reports

Emerging Roles for the Immune System in Traumatic Brain Injury

(2016) Celia A. McKee et al.   Frontiers in Immunology

Anti-high mobility group box-1 (HMGB1) antibody attenuates delayed cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats

(2016) Jun Haruma et al.   Scientific Reports

The HMGB1-RAGE Inflammatory Pathway: Implications for Brain Injury-Induced Pulmonary Dysfunction

(2015) Daniel J. Weber et al.   ANTIOXIDANTS & REDOX SIGNALING

Administration of DHA Reduces Endoplasmic Reticulum Stress-Associated Inflammation and Alters Microglial or Macrophage Activation in Traumatic Brain Injury

(2015) Lloyd D. Harvey et al.   ASN Neuro

Lipopolysaccharide preconditioning prevents acceleration of kindling epileptogenesis induced by traumatic brain injury

(2015) Mansoureh Eslami et al.   JOURNAL OF NEUROIMMUNOLOGY

Toll-like receptor 4 enhancement of non-NMDA synaptic currents increases dentate excitability after brain injury

(2015) Ying Li et al.   NEUROBIOLOGY OF DISEASE

Microglia-derived IL-1β triggers p53-mediated cell cycle arrest and apoptosis in neural precursor cells

(2015) J Guadagno et al.   Cell Death & Disease

Isoflurane preconditioning provides neuroprotection against stroke by regulating the expression of the TLR4 signalling pathway to alleviate microglial activation

(2015) Meiyan Sun et al.   Scientific Reports

Docosahexaenoic acid inhibits insulin-induced activation of sterol regulatory-element binding protein 1 and cyclooxygenase-2 expression through upregulation of SIRT1 in human colon epithelial cells

(2014) Na-Young Song et al.   BIOCHEMICAL PHARMACOLOGY

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

(2014) Hai-tao Zhu et al.   Journal of Neuroinflammation

Nutritional Treatment for Traumatic Brain Injury

(2014) Angus G. Scrimgeour et al.   JOURNAL OF NEUROTRAUMA

Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma

(2014) Tobias Bald et al.   NATURE

Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1–RAGE interaction

(2014) Yu Okuma et al.   NEUROPHARMACOLOGY

High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4

(2013) Melissa D. Laird et al.   GLIA

Omega-3 Polyunsaturated Fatty Acid Supplementation Improves Neurologic Recovery and Attenuates White Matter Injury after Experimental Traumatic Brain Injury

(2013) Hongjian Pu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Omega-3 Fatty Acids as a Putative Treatment for Traumatic Brain Injury

(2013) Linda Hasadsri et al.   JOURNAL OF NEUROTRAUMA

Melatonin promotes the in vitro development of pronuclear embryos and increases the efficiency of blastocyst implantation in murine

(2013) Feng Wang et al.   JOURNAL OF PINEAL RESEARCH

Omega-3 fatty acids and traumatic neurological injury: from neuroprotection to neuroplasticity?

(2013) Adina T. Michael-Titus et al.   TRENDS IN NEUROSCIENCES

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE