The BBSome: a nexus controlling energy metabolism in the brain

Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons

(2021) Liheng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs

(2020) Emily E. Burke et al.   Nature Communications

Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells

(2020) Takatoshi Kasai et al.   Cell Reports

Cilia signaling and obesity

(2020) Staci E. Engle et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Generation of an induced pluripotent stem cell line from an Alström Syndrome patient with ALMS1 mutation (c.3902C > A, c.6436C > T) and a gene correction isogenic iPSC line

(2020) Xiaoli Ji et al.   Stem Cell Research

Establishing and regulating the composition of cilia for signal transduction

(2019) Maxence V. Nachury et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity

(2018) Jacqueline E. Siljee et al.   NATURE GENETICS

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

(2018) Niels Grarup et al.   NATURE GENETICS

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

(2016) Xuyu Qian et al.   CELL

The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

(2016) Deng-Fu Guo et al.   PLoS Genetics

Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins

(2015) Rachel D. Starks et al.   PLoS Genetics

Patterning, specification, and differentiation in the developing hypothalamus

(2015) Joseph L. Bedont et al.   Wiley Interdisciplinary Reviews-Developmental Biology

From the cytoplasm into the cilium: Bon voyage

(2014) Jarema Malicki et al.   Organogenesis

BBS7 is required for BBSome formation and its absence in mice results in Bardet-Biedl syndrome phenotypes and selective abnormalities in membrane protein trafficking

(2013) Q. Zhang et al.   JOURNAL OF CELL SCIENCE

Bardet–Biedl syndrome

(2012) Elizabeth Forsythe et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Brain tissue- and region-specific abnormalities on volumetric MRI scans in 21 patients with Bardet-Biedl syndrome (BBS)

(2011) Kim M Keppler-Noreuil et al.   BMC Medical Genetics

Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

(2011) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leptin resistance contributes to obesity and hypertension in mouse models of Bardet-Biedl syndrome

(2008) Kamal Rahmouni et al.   JOURNAL OF CLINICAL INVESTIGATION