Differential pial and penetrating arterial responses examined by optogenetic activation of astrocytes and neurons

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*

(2020) Nathalie Percie du Sert et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurovascular and Cognitive Dysfunction in Hypertension

(2019) Costantino Iadecola et al.   CIRCULATION RESEARCH

How reliable is cerebral blood flow to map changes in neuronal activity?

(2019) Clotilde Lecrux et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Optogenetic assessment of VIP, PV, SOM and NOS inhibitory neuron activity and cerebral blood flow regulation in mouse somato-sensory cortex

(2019) Michael B Krawchuk et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocyte dysfunction and neurovascular impairment in neurological disorders: Correlation or causation?

(2019) Heather L. McConnell et al.   NEUROCHEMISTRY INTERNATIONAL

Key Aspects of Neurovascular Control Mediated by Specific Populations of Inhibitory Cortical Interneurons

(2019) L Lee et al.   CEREBRAL CORTEX

Modification of oxygen consumption and blood flow in mouse somatosensory cortex by cell-type-specific neuronal activity

(2019) Matilda K Dahlqvist et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Determinants of Optogenetic Cortical Spreading Depolarizations

(2018) David Y Chung et al.   CEREBRAL CORTEX

Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation

(2018) Norio Takata et al.   GLIA

Vascular Compartmentalization of Functional Hyperemia from the Synapse to the Pia

(2018) Ravi L. Rungta et al.   NEURON

Synchronized Astrocytic Ca 2+ Responses in Neurovascular Coupling during Somatosensory Stimulation and for the Resting State

(2018) Xiaochun Gu et al.   Cell Reports

Inhibitory Neuron Activity Contributions to Hemodynamic Responses and Metabolic Load Examined Using an Inhibitory Optogenetic Mouse Model

(2018) Alberto L Vazquez et al.   CEREBRAL CORTEX

Optical imaging and modulation of neurovascular responses

(2018) Kazuto Masamoto et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytes Integrate Behavioral State and Vascular Signals during Functional Hyperemia

(2018) Cam Ha T. Tran et al.   NEURON

What is the key mediator of the neurovascular coupling response?

(2018) Patrick S. Hosford et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Vascular Gap Junctions Contribute to Forepaw Stimulation-Induced Vasodilation Differentially in the Pial and Penetrating Arteries in Isoflurane-Anesthetized Rats

(2018) Nobuhiro Watanabe et al.   Frontiers in Molecular Neuroscience

Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

(2017) Stefano Tarantini et al.   EXPERIMENTAL GERONTOLOGY

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

(2017) Thomas A Longden et al.   NATURE NEUROSCIENCE

The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease

(2017) Costantino Iadecola   NEURON

Review: Astrocytes in Alzheimer's disease and other age-associated dementias: a supporting player with a central role

(2017) C. J. Garwood et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis

(2017) J. Duncombe et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mechanisms Mediating Functional Hyperemia in the Brain

(2017) Amy R. Nippert et al.   NEUROSCIENTIST

Light controls cerebral blood flow in naive animals

(2017) Ravi L Rungta et al.   Nature Communications

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer’s disease

(2017) Anna Csiszar et al.   GeroScience

Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications

(2016) Peter Toth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Uncoupling of neurovascular communication after transient global cerebral ischemia is caused by impaired parenchymal smooth muscle Kir channel function

(2016) Gro Klitgaard Povlsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Losartan improves cerebrovascular function in a mouse model of Alzheimer's disease with combined overproduction of amyloid-β and transforming growth factor-β1

(2016) Panayiota Papadopoulos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Optogenetic induction of cortical spreading depression in anesthetized and freely behaving mice

(2016) Thijs Houben et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Beyond neurovascular coupling, role of astrocytes in the regulation of vascular tone

(2016) J.A. Filosa et al.   NEUROSCIENCE

Cell type specificity of neurovascular coupling in cerebral cortex

(2016) Hana Uhlirova et al.   eLife

Venular degeneration leads to vascular dysfunction in a transgenic model of Alzheimer’s disease

(2015) Aaron Y. Lai et al.   BRAIN

Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer’s disease

(2015) Ian F. Kimbrough et al.   BRAIN

Astrocyte Ca2+ Signaling Drives Inversion of Neurovascular Coupling after Subarachnoid Hemorrhage

(2015) A. C. Pappas et al.   JOURNAL OF NEUROSCIENCE

Vascular Inward Rectifier K+Channels as External K+Sensors in the Control of Cerebral Blood Flow

(2015) Thomas A. Longden et al.   MICROCIRCULATION

Unveiling astrocytic control of cerebral blood flow with optogenetics

(2015) Kazuto Masamoto et al.   Scientific Reports

Pial Arteries Respond Earlier than Penetrating Arterioles to Neural Activation in the Somatosensory Cortex in Awake Mice Exposed to Chronic Hypoxia: An Additional Mechanism to Proximal Integration Signaling?

(2014) Yuta Sekiguchi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Critical Role for the Vascular Endothelium in Functional Neurovascular Coupling in the Brain

(2014) Brenda R. Chen et al.   Journal of the American Heart Association

Long-Term Adaptation of Cerebral Hemodynamic Response to Somatosensory Stimulation during Chronic Hypoxia in Awake Mice

(2013) Hiroyuki Takuwa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Layer-Specific Dilation of Penetrating Arteries Induced by Stimulation of the Nucleus Basalis of Meynert in the Mouse Frontal Cortex

(2013) Harumi Hotta et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Impairment of neurovascular coupling in type 1 diabetes mellitus in rats is linked to PKC modulation of BKCa and Kir channels

(2012) Francesco Vetri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease

(2012) Adrienne Dorr et al.   BRAIN

Pyramidal Cells and Cytochrome P450 Epoxygenase Products in the Neurovascular Coupling Response to Basal Forebrain Cholinergic Input

(2012) Clotilde Lecrux et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Repeated longitudinal in vivo imaging of neuro-glio-vascular unit at the peripheral boundary of ischemia in mouse cerebral cortex

(2012) K. Masamoto et al.   NEUROSCIENCE

Expanding the Repertoire of Optogenetically Targeted Cells with an Enhanced Gene Expression System

(2012) Kenji F. Tanaka et al.   Cell Reports

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity

(2011) P. J. Drew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytic endfoot Ca2+ and BK channels determine both arteriolar dilation and constriction

(2010) Hélène Girouard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal

(2010) P. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease

(2008) E. P. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitric oxide deficit in chronic intermittent hypoxia impairs large conductance calcium-activated potassium channel activity in rat hippocampal neurons

(2007) Yung-Wui Tjong et al.   FREE RADICAL BIOLOGY AND MEDICINE