Wogonin alleviates liver injury in sepsis through Nrf2‐mediated NF‐κB signalling suppression

Dosing vitamin C in critically ill patients with special attention to renal replacement therapy: a narrative review

(2020) Patrick M. Honore et al.   Annals of Intensive Care

A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein

(2020) Ziqiao Yuan et al.   Acta Pharmaceutica Sinica B

Lonicera caerulea L. Polyphenols Alleviate Oxidative Stress‐Induced Intestinal Environment Imbalance and Lipopolysaccharide‐Induced Liver Injury in HFD‐Fed Rats by Regulating the Nrf2/HO‐1/NQO1 and MAPK Pathways

(2020) Bin Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

MBD2-mediates septic AKI through activation of PKCη/ p38MAPK and the ERK1/2 axis

(2020) Yuxin Xie et al.   Molecular Therapy-Nucleic Acids

Histidine‐rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF‐κB and MAPK signal pathway

(2019) Shangze Gao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nephroprotective effect of wogonin against cadmium-induced nephrotoxicity via inhibition of oxidative stress–induced MAPK and NF-kB pathway in Sprague Dawley rats

(2019) D Jiao et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Necroptotic Cell Death in Liver Transplantation and Underlying Diseases: Mechanisms and Clinical Perspective

(2019) Shaojun Shi et al.   LIVER TRANSPLANTATION

The Reference Genome Sequence of Scutellaria baicalensis Provides Insights into the Evolution of Wogonin Biosynthesis

(2019) Qing Zhao et al.   Molecular Plant

Wogonin pre-treatment attenuates cisplatin-induced nephrotoxicity in rats: Impact on PPAR-γ, inflammation, apoptosis and Wnt/β-catenin pathway

(2019) Alaa M. Badawy et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Wogonin ameliorate complete Freund's adjuvant induced rheumatoid arthritis via targeting NF‐κB/MAPK signaling pathway

(2019) Yuntai Huang et al.   BIOFACTORS

The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model

(2019) Shidu Wu et al.   LIFE SCIENCES

Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation

(2019) Wan Bei et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Kupffer cell-derived TNF-α promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells

(2018) Li Su et al.   Cell Death & Disease

Liver dysfunction in sepsis

(2018) Ewa Woźnica et al.   Advances in Clinical and Experimental Medicine

Sestrin 2 confers primary resistance to sorafenib by simultaneously activating AKT and AMPK in hepatocellular carcinoma

(2018) Jimin Dai et al.   Cancer Medicine

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes

(2017) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Wogonin protects human retinal pigment epithelium cells from LPS-induced barrier dysfunction and inflammatory responses by regulating the TLR4/NF-κB signaling pathway

(2017) Chen Chen et al.   Molecular Medicine Reports

Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process

(2017) Jun Hyeon Choi et al.   Scientific Reports

Curcumin alleviates lipopolysaccharide induced sepsis and liver failure by suppression of oxidative stress-related inflammation via PI3K/AKT and NF-κB related signaling

(2016) Wenhui Zhong et al.   BIOMEDICINE & PHARMACOTHERAPY

Mangiferin alleviates lipopolysaccharide and D-galactosamine-induced acute liver injury by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

(2016) Chen-wei Pan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Liver — guardian, modifier and target of sepsis

(2016) Pavel Strnad et al.   Nature Reviews Gastroenterology & Hepatology

GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation

(2016) S Ito et al.   Cell Death & Disease

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Sepsis and septic shock

(2016) Richard S. Hotchkiss et al.   Nature Reviews Disease Primers

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Fluoride-induced oxidative stress is involved in the morphological damage and dysfunction of liver in female mice

(2015) Bian-hua Zhou et al.   CHEMOSPHERE

Flavonoids casticin and chrysosplenol D from Artemisia annua L. inhibit inflammation in vitro and in vivo

(2015) Yu-Jie Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Transcription Factors NRF2 and NF-κB Are Coordinated Effectors of the Rho Family, GTP-binding Protein RAC1 during Inflammation

(2014) Antonio Cuadrado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver sinusoidal endothelial dysfunction after LPS administration: A role for inducible-nitric oxide synthase

(2014) Vincenzo La Mura et al.   JOURNAL OF HEPATOLOGY

Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo

(2014) Soyoung Kwak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis

(2014) J Yao et al.   Cell Death & Disease

Extracellular ATP drives systemic inflammation, tissue damage and mortality

(2014) A Cauwels et al.   Cell Death & Disease

MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation

(2013) Yu-Jin Hwang et al.   Scientific Reports

The inflammatory response in sepsis

(2012) Markus Bosmann et al.   TRENDS IN IMMUNOLOGY

Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis

(2011) Xiaoni Kong et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reactive oxygen and mechanisms of inflammatory liver injury: Present concepts

(2011) Hartmut Jaeschke   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Pathogenesis of the hyperlipidemia of Gram-negative bacterial sepsis may involve pathomorphological changes in liver sinusoidal endothelial cells

(2010) Rajkumar Cheluvappa et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Hydrogen Gas Improves Survival Rate and Organ Damage in Zymosan-Induced Generalized Inflammation Model

(2010) Keliang Xie et al.   SHOCK

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

100% OXYGEN INHALATION PROTECTS AGAINST ZYMOSAN-INDUCED STERILE SEPSIS IN MICE

(2009) Lichao Hou et al.   SHOCK

The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

(2009) Brittany V. Martin-Murphy et al.   TOXICOLOGY LETTERS

Antiviral Activity of Nrf2 in a Murine Model of Respiratory Syncytial Virus Disease

(2008) Hye-Youn Cho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE