Exosome‐mediated pyroptosis of miR‐93‐TXNIP‐NLRP3 leads to functional difference between M1 and M2 macrophages in sepsis‐induced acute kidney injury

Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications

(2019) Chunyuan Guo et al.   Nature Reviews Nephrology

Protective Effect of Ethyl Pyruvate against Myocardial Ischemia Reperfusion Injury through Regulations of ROS-Related NLRP3 Inflammasome Activation

(2019) Ji Hae Jun et al.   Oxidative Medicine and Cellular Longevity

β-hydroxybutyrate attenuates renal ischemia-reperfusion injury through its anti-pyroptotic effects

(2019) Takaya Tajima et al.   KIDNEY INTERNATIONAL

The pathological features of regulated necrosis

(2019) Wulf Tonnus et al.   JOURNAL OF PATHOLOGY

Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway

(2019) Tao Zhang et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

TXNIP-mediated nuclear factor-κB signaling pathway and intracellular shifting of TXNIP in uric acid-induced NLRP3 inflammasome

(2019) Seong-Kyu Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury

(2019) Naijun Miao et al.   KIDNEY INTERNATIONAL

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

(2018) Zsolt Czimmerer et al.   IMMUNITY

mROS-TXNIP axis activates NLRP3 inflammasome to mediate renal injury during ischemic AKI

(2018) Yi Wen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

(2018) Takanori Komada et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E

(2018) Peiming Zheng et al.   Cell Death & Disease

Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis

(2018) Kimitoshi Kimura et al.   Nature Communications

Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury

(2018) Zhen Zhang et al.   Cell Death & Disease

Acute Kidney Injury

(2018) Ashley Farrar   NURSING CLINICS OF NORTH AMERICA

Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages

(2017) Shamila D. Alipoor et al.   Journal of Translational Medicine

MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression

(2017) Yun Teng et al.   Nature Communications

NLRP3 regulates a non-canonical platform for caspase-8 activation during epithelial cell apoptosis

(2016) H Chung et al.   CELL DEATH AND DIFFERENTIATION

Pyroptosis

(2016) Lieselotte Vande Walle et al.   CURRENT BIOLOGY

Recent advances in pathophysiology and biomarkers of sepsis-induced acute kidney injury

(2016) Ilaria Umbro et al.   JOURNAL OF INFECTION

Thioredoxin-Interacting Protein Mediates NLRP3 Inflammasome Activation Involved in the Susceptibility to Ischemic Acute Kidney Injury in Diabetes

(2016) Ye Da Xiao et al.   Oxidative Medicine and Cellular Longevity

cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAs

(2016) Tobias Fehlmann et al.   Clinical Epigenetics

Sepsis und Multiorganversagen – Pathophysiologie der Sepsis

(2015) Florian Uhle et al.   ANASTHESIOLOGIE INTENSIVMEDIZIN NOTFALLMEDIZIN SCHMERZTHERAPIE

Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling

(2015) Y.-Y. Yeh et al.   BLOOD

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Sepsis-Associated AKI: Epithelial Cell Dysfunction

(2015) David R. Emlet et al.   SEMINARS IN NEPHROLOGY

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

(2015) Jian Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Endotoxin and AKI: Macrophages Protect after Preconditioning

(2014) K. M. Yatim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulated Cell Death in AKI

(2014) A. Linkermann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Layered long-term co-culture of hepatocytes and endothelial cells on a transwell membrane: toward engineering the liver sinusoid

(2013) Young Bok (Abraham) Kang et al.   Biofabrication

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Activating Nrf-2 Signaling Depresses Unilateral Ureteral Obstruction-Evoked Mitochondrial Stress-Related Autophagy, Apoptosis and Pyroptosis in Kidney

(2012) Shue Dong Chung et al.   PLoS One

Coordinated Host Responses during Pyroptosis: Caspase-1-Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation

(2011) T. Bergsbaken et al.   JOURNAL OF IMMUNOLOGY

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Accuracy of Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Diagnosis and Prognosis in Acute Kidney Injury: A Systematic Review and Meta-analysis

(2009) Michael Haase et al.   AMERICAN JOURNAL OF KIDNEY DISEASES