Chrysin Improves Glucose and Lipid Metabolism Disorders by Regulating the AMPK/PI3K/AKT Signaling Pathway in Insulin-Resistant HepG2 Cells and HFD/STZ-Induced C57BL/6J Mice
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Chrysin Improves Glucose and Lipid Metabolism Disorders by Regulating the AMPK/PI3K/AKT Signaling Pathway in Insulin-Resistant HepG2 Cells and HFD/STZ-Induced C57BL/6J Mice
Authors
Keywords
-
Journal
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume -, Issue -, Pages -
Publisher
American Chemical Society (ACS)
Online
2021-05-13
DOI
10.1021/acs.jafc.1c01109
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Fermented Soy Paste Alleviates Lipid Accumulation in The Liver by Regulating the AMPK Pathway and Modulating Gut Microbiota in High-Fat Diet-Fed Rats
- (2020) Yen-Chen Tung et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Dietary Ginsenoside T19 Supplementation Regulates Glucose and Lipid Metabolism via AMPK and PI3K Pathways and Its Effect on Intestinal Microbiota
- (2020) Jing Xu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Impact of chrysin on the molecular mechanisms underlying diabetic complications
- (2019) Tahereh Farkhondeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cold‐pressed Canola Oil Reduces Hepatic Steatosis by Modulating Oxidative Stress and Lipid Metabolism in KM Mice Compared with Refined Bleached Deodorized Canola Oil
- (2019) Ying‐Jun Zhou et al. JOURNAL OF FOOD SCIENCE
- N-3 Polyunsaturated Fatty Acids Decrease Long-Term Diabetic Risk of Offspring of Gestational Diabetes Rats by Postponing Shortening of Hepatic Telomeres and Modulating Liver Metabolism
- (2019) Jinlong Gao et al. Nutrients
- WITHDRAWN: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9th edition
- (2019) Pouya Saeedi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Gymnemic Acid Ameliorates Hyperglycemia through PI3K/AKT- and AMPK-Mediated Signaling Pathways in Type 2 Diabetes Mellitus Rats
- (2019) Yumeng Li et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Chrysin: Pharmacological and therapeutic properties
- (2019) Saima Naz et al. LIFE SCIENCES
- Chrysin ameliorates cerebral ischemia/reperfusion (I/R) injury in rats by regulating the PI3K/Akt/mTOR pathway
- (2019) Teng-Fei Li et al. NEUROCHEMISTRY INTERNATIONAL
- A phenolic glycoside from Moringa oleifera Lam. improves the carbohydrate and lipid metabolisms through AMPK in db/db mice
- (2019) Yifan Bao et al. FOOD CHEMISTRY
- C-Phycocyanin inhibits hepatic gluconeogenesis and increases glycogen synthesis via activating Akt and AMPK in insulin resistance hepatocytes
- (2018) Zhiheng Ren et al. Food & Function
- Improvement in colistin-induced reproductive damage, apoptosis, and autophagy in testes via reducing oxidative stress by chrysin
- (2018) Emrah Hicazi Aksu et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Insulin resistance: Review of the underlying molecular mechanisms
- (2018) Habib Yaribeygi et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Chrysin leads to cell death in endometriosis by regulation of endoplasmic reticulum stress and cytosolic calcium level
- (2018) Soomin Ryu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Antidiabetic and hepatoprotective activity of the roots of Calanthe fimbriata Franch
- (2018) Yajie Peng et al. BIOMEDICINE & PHARMACOTHERAPY
- Caffeic Acid Phenethyl Ester (Propolis Extract) Ameliorates Insulin Resistance by Inhibiting JNK and NF-κB Inflammatory Pathways in Diabetic Mice and HepG2 Cell Models
- (2017) Jiarui Nie et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Chrysin attenuates progression of ovarian cancer cells by regulating signaling cascades and mitochondrial dysfunction
- (2017) Whasun Lim et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Chrysin Induces Antidiabetic, Antidyslipidemic and Anti-Inflammatory Effects in Athymic Nude Diabetic Mice
- (2017) Juan Ramírez-Espinosa et al. MOLECULES
- Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action
- (2017) Renuka Mani et al. PHYTOCHEMISTRY
- The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux
- (2016) Varman T. Samuel et al. JOURNAL OF CLINICAL INVESTIGATION
- Mulberry anthocyanin extract ameliorates insulin resistance by regulating PI3K/AKT pathway in HepG2 cells and db/db mice
- (2016) Fujie Yan et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Chrysin induces brown fat–like phenotype and enhances lipid metabolism in 3T3-L1 adipocytes
- (2016) Jae Heon Choi et al. NUTRITION
- Cancer risk of sulfonylureas in patients with type 2 diabetes mellitus: A systematic review
- (2016) Yuehong Chen et al. Journal of Diabetes
- Anti-inflammatory effect of AMPK signaling pathway in rat model of diabetic neuropathy
- (2016) Amin Hasanvand et al. INFLAMMOPHARMACOLOGY
- Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway
- (2015) Tao Zheng et al. BRITISH JOURNAL OF PHARMACOLOGY
- Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes
- (2015) T.-Y. Liu et al. CLINICAL SCIENCE
- Determination of Pharmacokinetics of Chrysin and Its Conjugates in Wild-Type FVB and Bcrp1 Knockout Mice Using a Validated LC-MS/MS Method
- (2015) Shufan Ge et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- The genetic architecture of NAFLD among inbred strains of mice
- (2015) Simon T Hui et al. eLife
- Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway
- (2013) Ai-Mei Gao et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats
- (2013) Shuai Zhang et al. FOOD CHEMISTRY
- Chrysin inhibits metastatic potential of human triple-negative breast cancer cells by modulating matrix metalloproteinase-10, epithelial to mesenchymal transition, and PI3K/Akt signaling pathway
- (2013) Bing Yang et al. JOURNAL OF APPLIED TOXICOLOGY
- AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells
- (2012) Jun-jie Shao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes
- (2009) Daniel J. Fazakerley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peroxisome proliferator-activated receptors and the metabolic syndrome
- (2007) M.C.E. Bragt et al. PHYSIOLOGY & BEHAVIOR
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More