The genetic architecture of NAFLD among inbred strains of mice

PROVEAN web server: a tool to predict the functional effect of amino acid substitutions and indels

(2015) Yongwook Choi et al.   BIOINFORMATICS

Genetic Architecture of Insulin Resistance in the Mouse

(2015) Brian W. Parks et al.   Cell Metabolism

Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers

(2014) Sebastian C. Hasenfuss et al.   Cell Metabolism

Systems biology for hepatologists

(2014) José M. Mato et al.   HEPATOLOGY

Increased expression of c-Jun in nonalcoholic fatty liver disease

(2014) Christoph Dorn et al.   LABORATORY INVESTIGATION

A comparative encyclopedia of DNA elements in the mouse genome

(2014) Feng Yue et al.   NATURE

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

(2013) Brian W. Parks et al.   Cell Metabolism

Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding

(2013) M. K. Montgomery et al.   DIABETOLOGIA

Metabolic Phenotyping and Systems Biology Approaches to Understanding Metabolic Syndrome and Fatty Liver Disease

(2013) Marc–Emmanuel Dumas et al.   GASTROENTEROLOGY

Intestinal microbiota in patients with nonalcoholic fatty liver disease

(2013) Marialena Mouzaki et al.   HEPATOLOGY

CD36-deficient mice are resistant to alcohol- and high-carbohydrate-induced hepatic steatosis

(2013) Robin D. Clugston et al.   JOURNAL OF LIPID RESEARCH

Systems genetics approaches to understand complex traits

(2013) Mete Civelek et al.   NATURE REVIEWS GENETICS

A variant in theLRRFIP1gene is associated with adiposity and inflammation

(2013) Melanie Plourde et al.   Obesity

Quantitative Trait Loci Affecting Liver Fat Content in Mice

(2013) Olga Minkina et al.   G3-Genes Genomes Genetics

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

(2013) Melanie Kahle et al.   Molecular Metabolism

The Functional Significance of Synaptotagmin Diversity in Neuroendocrine Secretion

(2013) Paanteha K. Moghadam et al.   Frontiers in Endocrinology

Unraveling Inflammatory Responses using Systems Genetics and Gene-Environment Interactions in Macrophages

(2012) Luz D. Orozco et al.   CELL

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH

(2012) Lixin Zhu et al.   HEPATOLOGY

Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease

(2012) Leon A. Adams et al.   HEPATOLOGY

Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms

(2012) J Gregory Caporaso et al.   ISME Journal

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing

(2012) Nicholas A Bokulich et al.   NATURE METHODS

Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice

(2012) Yan Y. Lam et al.   PLoS One

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Genetic modifiers of non-alcoholic fatty liver disease progression

(2011) Quentin M. Anstee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Insulin signaling to hepatic lipid metabolism in health and disease

(2011) Karla F. Leavens et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis

(2011) Patricia Lepage et al.   GASTROENTEROLOGY

Protein kinase Cβ deficiency attenuates obesity syndrome ofob/obmice by promoting white adipose tissue remodeling

(2011) Wei Huang et al.   JOURNAL OF LIPID RESEARCH

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

(2011) John C Chambers et al.   NATURE GENETICS

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Nonalcoholic Fatty Liver Disease

(2011) Krzysztof Lukasz Kopec et al.   NUTRITION IN CLINICAL PRACTICE

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Chronic Exposure to a High-Fat Diet Induces Hepatic Steatosis, Impairs Nitric Oxide Bioavailability, and Modifies the Mitochondrial Proteome in Mice

(2010) Heather B. Eccleston et al.   ANTIOXIDANTS & REDOX SIGNALING

Genome-Wide Association Study Identifies Variants Associated With Histologic Features of Nonalcoholic Fatty Liver Disease

(2010) Naga Chalasani et al.   GASTROENTEROLOGY

A high-resolution association mapping panel for the dissection of complex traits in mice

(2010) B. J. Bennett et al.   GENOME RESEARCH

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

(2010) Alan W Walker et al.   ISME Journal

A Novel Glycerophosphodiester Phosphodiesterase, GDE5, Controls Skeletal Muscle Development via a Non-enzymatic Mechanism

(2010) Yuri Okazaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A position statement on NAFLD/NASH based on the EASL 2009 special conference

(2010) Vlad Ratziu et al.   JOURNAL OF HEPATOLOGY

Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo

(2010) Gabriel M. Simon et al.   Molecular BioSystems

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Switch from Stress Response to Homeobox Transcription Factors in Adipose Tissue After Profound Fat Loss

(2010) Simon N. Dankel et al.   PLoS One

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamine, arginine, and leucine signaling in the intestine

(2009) J. Marc Rhoads et al.   AMINO ACIDS

Dissecting the role of insulin resistance in the metabolic syndrome

(2009) Joel T Haas et al.   CURRENT OPINION IN LIPIDOLOGY

Heritability of Nonalcoholic Fatty Liver Disease

(2009) Jeffrey B. Schwimmer et al.   GASTROENTEROLOGY

Loss of protein kinase Cβ function protects mice against diet-induced obesity and development of hepatic steatosis and insulin resistance

(2009) Wei Huang et al.   HEPATOLOGY

Diet-induced hepatocellular carcinoma in genetically predisposed mice

(2009) A. E. Hill-Baskin et al.   HUMAN MOLECULAR GENETICS

Synaptotagmin-7 is a principal Ca2+sensor for Ca2+-induced glucagon exocytosis in pancreas

(2009) Natalia Gustavsson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17

(2009) Carrie A. Millward et al.   MAMMALIAN GENOME

A customized and versatile high-density genotyping array for the mouse

(2009) Hyuna Yang et al.   NATURE METHODS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Effects of atherogenic diet on hepatic gene expression across mouse strains

(2009) Keith R. Shockley et al.   PHYSIOLOGICAL GENOMICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Community Variation in Human Body Habitats Across Space and Time

(2009) E. K. Costello et al.   SCIENCE

Arginine metabolism and nutrition in growth, health and disease

(2008) Guoyao Wu et al.   AMINO ACIDS

High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial functionin vivo

(2008) Sudheer K. Mantena et al.   BIOCHEMICAL JOURNAL

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Ethnic differences in hepatic steatosis: An insulin resistance paradox?

(2008) Richard Guerrero et al.   HEPATOLOGY

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Error-correcting barcoded primers for pyrosequencing hundreds of samples in multiplex

(2008) Micah Hamady et al.   NATURE METHODS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

(2008) N. Gustavsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective

(2008) Mariana Lazo et al.   SEMINARS IN LIVER DISEASE

Nonalcoholic fatty liver disease: An overview of current insights in pathogenesis, diagnosis and treatment

(2008) Tim CMA Schreuder et al.   WORLD JOURNAL OF GASTROENTEROLOGY