Endothelial Autocrine Signaling through CXCL12/CXCR4/FoxM1 Axis Contributes to Severe Pulmonary Arterial Hypertension

Endothelial Cells in the Pathogenesis of Pulmonary Arterial Hypertension

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Mural Cell SDF1 Signaling is Associated with the Pathogenesis of Pulmonary Arterial Hypertension

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Lineage Tracing Reveals the Dynamic Contribution of Pericytes to the Blood Vessel Remodeling in Pulmonary Hypertension

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CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease

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Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension

(2019) Diederik E Van der Feen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neutralization of CXCL12 attenuates established pulmonary hypertension in rats

(2019) Jennifer Bordenave et al.   CARDIOVASCULAR RESEARCH

Participation of PLK1 and FOXM1 in the hyperplastic proliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension

(2019) Jamie L. Wilson et al.   PLoS One

Endothelial and Smooth Muscle Cell Interaction via FoxM1 Signaling Mediates Vascular Remodeling and Pulmonary Hypertension

(2018) Zhiyu Dai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Therapeutic Targeting of Vascular Remodeling and Right Heart Failure in PAH with HIF-2α Inhibitor

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Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research

(2018) Steeve Provencher et al.   CIRCULATION RESEARCH

Ephrin receptor A2 is a functional entry receptor for Epstein–Barr virus

(2018) Jia Chen et al.   Nature Microbiology

Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension

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Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome

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Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

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Haemodynamic definitions and updated clinical classification of pulmonary hypertension

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Foxm1 is a critical driver of TGF-β-induced EndMT in endothelial cells through Smad2/3 and binds to the Snail promoter

(2018) Shuai Song et al.   JOURNAL OF CELLULAR PHYSIOLOGY

FOXM1 promotes pulmonary artery smooth muscle cell expansion in pulmonary arterial hypertension

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Discovery of a murine model of clinical PAH: Mission impossible?

(2017) Zhiyu Dai et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Endothelial p110γPI3K Mediates Endothelial Regeneration and Vascular Repair After Inflammatory Vascular InjuryCLINICAL PERSPECTIVE

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Prolyl-4 Hydroxylase 2 (PHD2) Deficiency in Endothelial Cells and Hematopoietic Cells Induces Obliterative Vascular Remodeling and Severe Pulmonary Arterial Hypertension in Mice and Humans Through Hypoxia-Inducible Factor-2αCLINICAL PERSPECTIVE

(2016) Zhiyu Dai et al.   CIRCULATION

RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension

(2015) Christopher J. Rhodes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

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CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

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CXCL12 Signaling Is Essential for Maturation of the Ventricular Coronary Endothelial Plexus and Establishment of Functional Coronary Circulation

(2015) Susana Cavallero et al.   DEVELOPMENTAL CELL

The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development

(2015) Sarah Ivins et al.   DEVELOPMENTAL CELL

Tissue-based map of the human proteome

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Elevated Plasma CXCL12α Is Associated with a Poorer Prognosis in Pulmonary Arterial Hypertension

(2015) Brian N. McCullagh et al.   PLoS One

CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit+ Cells in Rats

(2014) Daniela Farkas et al.   PLoS One

Autocrine Fibroblast Growth Factor-2 Signaling Contributes to Altered Endothelial Phenotype in Pulmonary Hypertension

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FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of β-catenin expression

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Inhibition of the SDF-1/CXCR4 Axis Attenuates Neonatal Hypoxia-Induced Pulmonary Hypertension

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