Lineage Tracing Reveals the Dynamic Contribution of Pericytes to the Blood Vessel Remodeling in Pulmonary Hypertension

Loss of Endothelial Derived WNT5A is Associated with Reduced Pericyte Recruitment and Small Vessel Loss in Pulmonary Arterial Hypertension

(2019) Ke Yuan et al.   CIRCULATION

Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension

(2019) Ly Tu et al.   CIRCULATION RESEARCH

The pericyte microenvironment during vascular development

(2019) Laura B. Payne et al.   MICROCIRCULATION

Neutralization of CXCL12 attenuates established pulmonary hypertension in rats

(2019) Jennifer Bordenave et al.   CARDIOVASCULAR RESEARCH

Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension

(2018) Yuichi Tamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Resident cell lineages are preserved in pulmonary vascular remodeling

(2018) Slaven Crnkovic et al.   JOURNAL OF PATHOLOGY

Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension

(2018) Abdul Q. Sheikh et al.   Cell Reports

Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia

(2018) Pierre Regenass et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Haemodynamic definitions and updated clinical classification of pulmonary hypertension

(2018) Gérald Simonneau et al.   EUROPEAN RESPIRATORY JOURNAL

Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension

(2018) Paul-Benoit Poble et al.   FASEB JOURNAL

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

(2017) Tomoko Yamazaki et al.   Cell Reports

Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension

(2016) Ke Yuan et al.   AMERICAN JOURNAL OF PATHOLOGY

A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension

(2016) Lai-Ming Yung et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Jagged1/Notch3 Signaling Modulates Hemangioma-Derived Pericyte Proliferation and Maturation

(2016) Yi Ji et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Resident PW1+Progenitor Cells Participate in Vascular Remodeling During Pulmonary Arterial HypertensionNovelty and Significance

(2016) France Dierick et al.   CIRCULATION RESEARCH

In Vivo Study of Human Endothelial-Pericyte Interaction Using the Matrix Gel Plug Assay in Mouse

(2016) Ke Yuan et al.   Jove-Journal of Visualized Experiments

Activation of the Wnt/Planar Cell Polarity Pathway Is Required for Pericyte Recruitment during Pulmonary Angiogenesis

(2015) Ke Yuan et al.   AMERICAN JOURNAL OF PATHOLOGY

Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex

(2015) Morane Le Hiress et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Perlecan heparan sulfate deficiency impairs pulmonary vascular development and attenuates hypoxic pulmonary hypertension

(2015) Y.-T. Chang et al.   CARDIOVASCULAR RESEARCH

Leptin signalling system as a target for pulmonary arterial hypertension therapy

(2015) Alice Huertas et al.   EUROPEAN RESPIRATORY JOURNAL

Elevated Plasma CXCL12α Is Associated with a Poorer Prognosis in Pulmonary Arterial Hypertension

(2015) Brian N. McCullagh et al.   PLoS One

Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension

(2014) Nicolas Ricard et al.   CIRCULATION

CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit+ Cells in Rats

(2014) Daniela Farkas et al.   PLoS One

A Critical Role for p130Casin the Progression of Pulmonary Hypertension in Humans and Rodents

(2012) Ly Tu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Novel Murine Model of Severe Pulmonary Arterial Hypertension

(2011) Loredana Ciuclan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

(2011) S. Farha et al.   BLOOD

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

A role for the CXCL12 receptor, CXCR7, in the pathogenesis of human pulmonary vascular disease

(2011) Christine M. Costello et al.   EUROPEAN RESPIRATORY JOURNAL

Autocrine Fibroblast Growth Factor-2 Signaling Contributes to Altered Endothelial Phenotype in Pulmonary Hypertension

(2010) Ly Tu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Targeting of c-kit+ haematopoietic progenitor cells prevents hypoxic pulmonary hypertension

(2010) N. Gambaryan et al.   EUROPEAN RESPIRATORY JOURNAL

Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

(2010) Franck Lebrin et al.   NATURE MEDICINE

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

(2009) C. Guignabert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Small Neutralizing Molecules to Inhibit Actions of the Chemokine CXCL12

(2008) Muriel Hachet-Haas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY