Effective Drug Concentration and Selectivity Depends on Fraction of Primitive Cells
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Effective Drug Concentration and Selectivity Depends on Fraction of Primitive Cells
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 9, Pages 4931
Publisher
MDPI AG
Online
2021-05-06
DOI
10.3390/ijms22094931
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts
- (2021) Jeffrey J. Quinn et al. SCIENCE
- Short-Term versus Long-Term Culture of A549 Cells for Evaluating the Effects of Lipopolysaccharide on Oxidative Stress, Surfactant Proteins and Cathelicidin LL-37
- (2020) Zuzana Nova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Long-term ex vivo expansion of mouse hematopoietic stem cells
- (2020) Adam C. Wilkinson et al. Nature Protocols
- On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology
- (2020) David B. Chou et al. Nature Biomedical Engineering
- Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia
- (2020) Andrew P. Michelson et al. Scientific Reports
- Molywood: streamlining the design and rendering of molecular movies
- (2020) Miłosz Wieczór et al. BIOINFORMATICS
- IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells
- (2020) Ling Gong et al. BMC Pulmonary Medicine
- Targeting of Lung Cancer Stem Cell Self-Renewal Pathway by a Small Molecule Verrucarin J
- (2019) Karen Udoh et al. Stem Cell Reviews and Reports
- A computational model of feedback-mediated hematopoietic stem cell differentiation in vitro
- (2019) Bhushan Mahadik et al. PLoS One
- The concept of leukaemic stem cells in acute myeloid leukaemia 25 years on: hitting a moving target
- (2019) Peter Hokland et al. BRITISH JOURNAL OF HAEMATOLOGY
- Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
- (2018) Jan J. Lica et al. STEM CELLS AND DEVELOPMENT
- BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells
- (2018) Taeho Kwon et al. Cell Death & Disease
- Hirsutine induces mPTP-dependent apoptosis through ROCK1/PTEN/PI3K/GSK3β pathway in human lung cancer cells
- (2018) Rong Zhang et al. Cell Death & Disease
- Utilization of lung cancer cell lines for the study of lung cancer stem cells (Review)
- (2018) Yuyi Wang et al. Oncology Letters
- The Novel Small Molecule STK899704 Promotes Senescence of the Human A549 NSCLC Cells by Inducing DNA Damage Responses and Cell Cycle Arrest
- (2018) Chan-Woo Park et al. Frontiers in Pharmacology
- Harmonic Force Constants for Molecular Mechanics Force Fields via Hessian Matrix Projection
- (2017) Alice E. A. Allen et al. Journal of Chemical Theory and Computation
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells
- (2017) Zhaorui Zhang et al. PLoS One
- Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell–mediated TNFα signaling
- (2017) Weijia Wang et al. Science Translational Medicine
- Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
- (2017) Majus Misiak et al. Oncotarget
- Glioma‐derived cancer stem cells are hypersensitive to proteasomal inhibition
- (2016) Young Dong Yoo et al. EMBO REPORTS
- Cytotoxicity, Post-Treatment Recovery, and Selectivity Analysis of Naturally Occurring Podophyllotoxins from Bursera fagaroides var. fagaroides on Breast Cancer Cell Lines
- (2016) Omar Peña-Morán et al. MOLECULES
- Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype
- (2016) James Ross Cooper et al. PLoS One
- Side population cells from long-term passage non-small cell lung cancer cells display loss of cancer stem cell-like properties and chemoradioresistance
- (2016) Hao Gu et al. Oncology Letters
- Label-free enumeration, collection and downstream cytological and cytogenetic analysis of circulating tumor cells
- (2016) Manjima Dhar et al. Scientific Reports
- All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies
- (2015) Miguel A. Sanz et al. ANNALS OF HEMATOLOGY
- Cell Division Patterns in Acute Myeloid Leukemia Stem-like Cells Determine Clinical Course: A Model to Predict Patient Survival
- (2015) T. Stiehl et al. CANCER RESEARCH
- Parmbsc1: a refined force field for DNA simulations
- (2015) Ivan Ivani et al. NATURE METHODS
- Cytotoxicity screening of essential oils in cancer cell lines
- (2015) Pollyanna Francielli de Oliveira et al. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy
- Predictions for optimal mitigation of paracrine inhibitory signalling in haemopoietic stem cell cultures
- (2015) Joseph D Berry et al. Stem Cell Research & Therapy
- Cytotoxicity screening of essential oils in cancer cell lines
- (2015) Pollyanna Francielli de Oliveira et al. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy
- Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture
- (2015) Claire M. Doskey et al. PLoS One
- Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
- (2014) Liran I. Shlush et al. NATURE
- Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
- (2014) Yao-Cheng Lin et al. Nature Communications
- GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
- (2013) Sander Pronk et al. BIOINFORMATICS
- Automated method for the rapid and precise estimation of adherent cell culture characteristics from phase contrast microscopy images
- (2013) Nicolas Jaccard et al. BIOTECHNOLOGY AND BIOENGINEERING
- Cancer heterogeneity: implications for targeted therapeutics
- (2013) R Fisher et al. BRITISH JOURNAL OF CANCER
- PLUMED 2: New feathers for an old bird
- (2013) Gareth A. Tribello et al. COMPUTER PHYSICS COMMUNICATIONS
- Size-Based Isolation of Circulating Tumor Cells in Lung Cancer Patients Using a Microcavity Array System
- (2013) Masahito Hosokawa et al. PLoS One
- TGF-β1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133+ A549 cell fraction
- (2013) V Tirino et al. Cell Death & Disease
- Analyzing and Building Nucleic Acid Structures with 3DNA
- (2013) Andrew V. Colasanti et al. Jove-Journal of Visualized Experiments
- Rapid Expansion of Human Hematopoietic Stem Cells by Automated Control of Inhibitory Feedback Signaling
- (2012) Elizabeth Csaszar et al. Cell Stem Cell
- Clonal Architecture of Secondary Acute Myeloid Leukemia
- (2012) Matthew J. Walter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
- (2012) M. Jan et al. Science Translational Medicine
- Low-density expansion protects human synovium-derived stem cells from replicative senescence: a preliminary study
- (2012) Jingting Li et al. Drug Delivery and Translational Research
- Human Acute Myelogenous Leukemia Stem Cells Revisited: There's More Than Meets the Eye
- (2011) Ravindra Majeti et al. CANCER CELL
- Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia
- (2011) Nicolas Goardon et al. CANCER CELL
- Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: Implications for drug resistance and in vitro drug screening models
- (2011) Michal Sabisz et al. CELL CYCLE
- Identifying Inhibitors of Epithelial-Mesenchymal Transition by Connectivity Map–Based Systems Approach
- (2011) Ajaya Kumar Reka et al. Journal of Thoracic Oncology
- Preoperative Circulating Tumor Cell Detection Using the Isolation by Size of Epithelial Tumor Cell Method for Patients with Lung Cancer Is a New Prognostic Biomarker
- (2010) V. Hofman et al. CLINICAL CANCER RESEARCH
- Molecular dynamics simulation with weak coupling to heat and material baths
- (2010) Hossein Eslami et al. JOURNAL OF CHEMICAL PHYSICS
- Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells
- (2010) Leilei Tang et al. BMC Pharmacology & Toxicology
- Targeting the leukemic stem cell: the Holy Grail of leukemia therapy
- (2008) N Misaghian et al. LEUKEMIA
- Topoisomerase II Negatively Modulates Retinoic Acid Receptor Function: a Novel Mechanism of Retinoic Acid Resistance
- (2008) S. McNamara et al. MOLECULAR AND CELLULAR BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started