Short-Term versus Long-Term Culture of A549 Cells for Evaluating the Effects of Lipopolysaccharide on Oxidative Stress, Surfactant Proteins and Cathelicidin LL-37

Alveolar-Capillary Membrane-Related Pulmonary Cells as a Target in Endotoxin-Induced Acute Lung Injury

(2019) Zuzana Nova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Peptide Inhibitor of NADPH Oxidase (NOX2) Activation Markedly Decreases Mouse Lung Injury and Mortality Following Administration of Lipopolysaccharide (LPS)

(2019) Aron B. Fisher et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Downregulation of p300 alleviates LPS-induced inflammatory injuries through regulation of RhoA/ROCK/NF-κB pathways in A549 cells

(2018) Qiang Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Tremella polysaccharides inhibit cellular apoptosis and autophagy induced by Pseudomonas�aeruginosa lipopolysaccharide in A549 cells through sirtuin 1 activation

(2018) Xiaolan Shi et al.   Oncology Letters

Low concentration of oleic acid exacerbates LPS-induced cell death and inflammation in human alveolar epithelial cells

(2017) Altug Kucukgul et al.   EXPERIMENTAL LUNG RESEARCH

Site-specific and endothelial-mediated dysfunction of the alveolar-capillary barrier in response to lipopolysaccharides

(2017) Harshavardhan Janga et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Apoptosis and surfactant protein-C expression inhibition induced by lipopolysaccharide in AEC II cell may associate with NF-κB pathway

(2017) Jinle Lin et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Ghrelin ameliorates the human alveolar epithelial A549 cell apoptosis induced by lipopolysaccharide

(2016) Chunrong Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation of 5-HT7 Receptor Trafficking on In Vivo and In Vitro Model of Lipopolysaccharide (LPS)-Induced Inflammatory Cell Injury in Rats and LPS-Treated A549 Cells

(2016) Gulsen Ayaz et al.   BIOCHEMICAL GENETICS

Antimicrobial Peptides and Innate Lung Defenses

(2016) Pieter S. Hiemstra et al.   CHEST

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype

(2016) James Ross Cooper et al.   PLoS One

Specific Lipopolysaccharide Serotypes Induce Differential Maternal and Neonatal Inflammatory Responses in a Murine Model of Preterm Labor

(2015) Roberta Migale et al.   AMERICAN JOURNAL OF PATHOLOGY

Lipopolysaccharide Induces Autophagic Cell Death through the PERK-Dependent Branch of the Unfolded Protein Response in Human Alveolar Epithelial A549 Cells

(2015) Shaoying Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Picfeltarraenin IA inhibits lipopolysaccharide-induced inflammatory cytokine production by the nuclear factor-κB pathway in human pulmonary epithelial A549 cells

(2015) RONG SHI et al.   Oncology Letters

Oxidation pathway and exacerbations in COPD: the role of NAC

(2015) Maria Gabriella Matera et al.   Expert Review of Respiratory Medicine

Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2)

(2014) Intae Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

miR-135a inhibition protects A549 cells from LPS-induced apoptosis by targeting Bcl-2

(2014) Jing Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Different mechanism of LPS-induced calcium increase in human lung epithelial cell and microvascular endothelial cell: a cell culture study in a model for ARDS

(2014) Kejing Zhang et al.   MOLECULAR BIOLOGY REPORTS

Oxygen Toxicity

(2014) Louise Thomson et al.   Paediatric Respiratory Reviews

LPS-Treated Macrophage Cytokines Repress Surfactant Protein–B in Lung Epithelial Cells

(2013) Kiflai Bein et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Kinetic and mechanistic considerations to assess the biological fate of peroxynitrite

(2013) Sebastián Carballal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

SIRT1 Regulates the Human Alveolar Epithelial A549 Cell Apoptosis Induced byPseudomonas AeruginosaLipopolysaccharide

(2013) Xiaoli Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Anti-inflammatory effects of anethole in lipopolysaccharide-induced acute lung injury in mice

(2013) Purum Kang et al.   LIFE SCIENCES

Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

(2013) Gordon F. Rushworth et al.   PHARMACOLOGY & THERAPEUTICS

Mechanisms mediating propofol protection of pulmonary epithelial cells against lipopolysaccharide-induced cell death

(2012) Xiaoxia Gu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

The effect of human antibacterial peptide LL-37 in the pathogenesis of chronic obstructive pulmonary disease

(2012) Yuan-Yuan Jiang et al.   RESPIRATORY MEDICINE

A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: Modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium

(2011) John J. Haddad   CELLULAR IMMUNOLOGY

Lipopolysaccharide stimulates syntheses of toll-like receptor 2 and surfactant protein-A in human alveolar epithelial A549 cells through upregulating phosphorylation of MEK1 and ERK1/2 and sequential activation of NF-κB

(2011) Tsu-Tuan Wu et al.   CYTOKINE

Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells

(2011) Kaori Suzuki et al.   INTERNATIONAL IMMUNOLOGY

Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

(2011) Andrew J. Thorley et al.   PLoS One

Lipopolysaccharide induces apoptotic insults to human alveolar epithelial A549 cells through reactive oxygen species-mediated activation of an intrinsic mitochondrion-dependent pathway

(2010) Chi-Yuan Chuang et al.   ARCHIVES OF TOXICOLOGY

Cathelicidin LL-37: A Multitask Antimicrobial Peptide

(2010) Robert Bucki et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Assessment of Cell Line Models of Primary Human Cells by Raman Spectral Phenotyping

(2010) Robin J. Swain et al.   BIOPHYSICAL JOURNAL

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

N-acetylcysteine protects alveolar epithelial cells from hydrogen peroxide–induced apoptosis through scavenging reactive oxygen species and suppressing c-Jun N-terminalkinase

(2010) Yue-qiang Fu et al.   EXPERIMENTAL LUNG RESEARCH

The role of lipopolysaccharide moieties in macrophage response to Escherichia coli

(2009) Katalin Eder et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Low concentrations of LL-37 alter IL-8 production by keratinocytes and bronchial epithelial cells in response to proinflammatory stimuli

(2009) Niall C.J. Filewod et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Molecular mechanisms of lipopolysaccharide-caused induction of surfactant protein-A gene expression in human alveolar epithelial A549 cells

(2009) Chi-Yuan Chuang et al.   TOXICOLOGY LETTERS

Expression and Secretion of Cathelicidin LL-37 in Human Epithelial Cells after Infection by Mycobacterium bovis Bacillus Calmette-Guerin

(2008) P. Mendez-Samperio et al.   Clinical and Vaccine Immunology

The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine

(2008) Mandana Moradi et al.   RESPIRATORY MEDICINE