Immune response scenario and vaccine development for SARS-CoV-2 infection

Learning from the Past: Possible Urgent Prevention and Treatment Options for Severe Acute Respiratory Infections Caused by 2019‐nCoV

(2020) Jared S. Morse et al.   CHEMBIOCHEM

Recent discovery and development of inhibitors targeting coronaviruses

(2020) Thanigaimalai Pillaiyar et al.   DRUG DISCOVERY TODAY

Evidence for gastrointestinal infection of SARS-CoV-2

(2020) Fei Xiao et al.   GASTROENTEROLOGY

Potential interventions for novel coronavirus in China: A systematic review

(2020) Lei Zhang et al.   JOURNAL OF MEDICAL VIROLOGY

Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS

(2020) Yushun Wan et al.   JOURNAL OF VIROLOGY

Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding

(2020) Roujian Lu et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China

(2020) Fei Yu et al.   MICROBES AND INFECTION

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Covid-19 — Navigating the Uncharted

(2020) Anthony S. Fauci et al.   NEW ENGLAND JOURNAL OF MEDICINE

New coronavirus threat galvanizes scientists

(2020) Jon Cohen   SCIENCE

Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein

(2020) Junghyun Goo et al.   VIRUS RESEARCH

Characterization of the Immune Response of MERS-CoV Vaccine Candidates Derived from Two Different Vectors in Mice

(2020) Entao Li et al.   Viruses-Basel

Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies

(2020) Syed Faraz Ahmed et al.   Viruses-Basel

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies

(2020) Shibo Jiang et al.   Emerging Microbes & Infections

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Neuropathology of COVID-19: a spectrum of vascular and acute disseminated encephalomyelitis (ADEM)-like pathology

(2020) R. Ross Reichard et al.   ACTA NEUROPATHOLOGICA

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome

(2020) Toshio Hirano et al.   IMMUNITY

SARS-CoV-2 Vaccines: Status Report

(2020) Fatima Amanat et al.   IMMUNITY

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

(2020) Chi Zhang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Towards effective COVID‑19 vaccines: Updates, perspectives and challenges (Review)

(2020) Daniela Calina et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Author Correction: A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Antibody responses to SARS-CoV-2 in patients with COVID-19

(2020) Quan-Xin Long et al.   NATURE MEDICINE

COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics

(2020) Kuldeep Dhama et al.   Human Vaccines & Immunotherapeutics

Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection

(2020) Xin Zou et al.   Frontiers of Medicine

Elevated plasma level of selective cytokines in COVID-19 patients reflect viral load and lung injury

(2020) Yingxia Liu et al.   National Science Review

Phase 1/2 study of COVID-19 RNA vaccine BNT162b1 in adults

(2020) Mark J. Mulligan et al.   NATURE

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune Response, Inflammation, and the Clinical Spectrum of COVID-19

(2020) Luis F. García   Frontiers in Immunology

Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study

(2020) Cristina Basso et al.   EUROPEAN HEART JOURNAL

SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

(2020) Gregory A Poland et al.   LANCET

Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults

(2020) Evan J. Anderson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathologic features of COVID-19: A concise review

(2020) Mohammadreza Tabary et al.   PATHOLOGY RESEARCH AND PRACTICE

Double-Stranded RNA Sensors and Modulators in Innate Immunity

(2019) Sun Hur   Annual Review of Immunology

Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines

(2019) Masaaki Murakami et al.   IMMUNITY

Human Coronavirus: Host-Pathogen Interaction

(2019) To Sing Fung et al.   Annual Review of Microbiology

Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus

(2019) Myung Hee Kim et al.   PLoS One

Coronaviren als Ursache respiratorischer Infektionen

(2019) V. M. Corman et al.   INTERNIST

Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus

(2019) Chean Yeah Yong et al.   Frontiers in Microbiology

TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infection

(2019) Marine de Marcken et al.   Science Signaling

Identification of the immunodominant neutralizing regions in the spike glycoprotein of porcine deltacoronavirus

(2019) Rui Chen et al.   VIRUS RESEARCH

Sphingosine-1-phosphate receptors and innate immunity

(2018) Arielle M. Bryan et al.   CELLULAR MICROBIOLOGY

Understanding Angiotensin II Type 1 Receptor Signaling in Vascular Pathophysiology

(2018) Satoru Eguchi et al.   HYPERTENSION

Salivary C-reactive protein, mean platelet volume and neutrophil lymphocyte ratio as diagnostic markers for neonatal sepsis

(2018) Ahmed Omran et al.   Jornal de Pediatria

Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism

(2018) Watee Seesuay et al.   Emerging Microbes & Infections

Prospects for a MERS-CoV spike vaccine

(2018) Yusen Zhou et al.   Expert Review of Vaccines

Toll-like receptor 4 in acute viral infection: Too much of a good thing

(2018) Judith Olejnik et al.   PLoS Pathogens

Analysis of the genome sequence and prediction of B-cell epitopes of the envelope protein of Middle East respiratory syndrome-coronavirus

(2017) Qian Xie et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Cross-neutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses

(2017) Lei-Ping Zeng et al.   Science China-Life Sciences

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

(2015) Jasper F. W. Chan et al.   CLINICAL MICROBIOLOGY REVIEWS

Molecular mechanisms for enhanced DNA vaccine immunogenicity

(2015) Lei Li et al.   Expert Review of Vaccines

Receptor-binding domain-based subunit vaccines against MERS-CoV

(2015) Naru Zhang et al.   VIRUS RESEARCH

Animal models for SARS and MERS coronaviruses

(2015) Lisa M Gretebeck et al.   Current Opinion in Virology

IL-6 in diabetes and cardiovascular complications

(2014) Dan Qu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection

(2014) J. R. Teijaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infection with MERS-CoV Causes Lethal Pneumonia in the Common Marmoset

(2014) Darryl Falzarano et al.   PLoS Pathogens

Inhibitory effects of suppressor of cytokine signaling 3 on inflammatory cytokine expression and migration and proliferation of IL-6/IFN-γ-induced vascular smooth muscle cells

(2013) Shui Xiang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Inhibition of NF- B-Mediated Inflammation in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice Increases Survival

(2013) M. L. DeDiego et al.   JOURNAL OF VIROLOGY

A decade after SARS: strategies for controlling emerging coronaviruses

(2013) Rachel L. Graham et al.   NATURE REVIEWS MICROBIOLOGY

Pneumonia from Human Coronavirus in a Macaque Model

(2013) Vincent J. Munster et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

Clinical Applications of DNA Vaccines: Current Progress

(2011) B. Ferraro et al.   CLINICAL INFECTIOUS DISEASES

A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge

(2011) M. Bolles et al.   JOURNAL OF VIROLOGY

Anti-TNF-α agents in the treatment of immune-mediated inflammatory diseases: mechanisms of action and pitfalls

(2010) Léia CR Silva et al.   Immunotherapy

Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates

(2010) Saskia L. Smits et al.   PLoS Pathogens

Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63

(2009) I. Glowacka et al.   JOURNAL OF VIROLOGY

Modulation of TNF- -converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-  production and facilitates viral entry

(2008) S. Haga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal models and vaccines for SARS-CoV infection

(2007) Anjeanette Roberts et al.   VIRUS RESEARCH