Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children

An immune-cell signature of bacterial sepsis

(2020) Miguel Reyes et al.   NATURE MEDICINE

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

(2020) Francesca Coperchini et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Multisystem Inflammatory Syndrome with Features of Atypical Kawasaki Disease during COVID-19 Pandemic

(2020) Abdul Rauf et al.   INDIAN JOURNAL OF PEDIATRICS

Hyperinflammatory shock in children during COVID-19 pandemic

(2020) Shelley Riphagen et al.   LANCET

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

(2020) Lucio Verdoni et al.   LANCET

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

(2020) Zhiwei Zhou et al.   SCIENCE

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

(2020) Jonas Schulte-Schrepping et al.   CELL

Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2

(2020) Elizabeth Whittaker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

(2020) Eva W. Cheung et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

Multisystem Inflammatory Syndrome in U.S. Children and Adolescents

(2020) Leora R. Feldstein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

(2020) Jérôme Hadjadj et al.   SCIENCE

Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study

(2020) Julie Toubiana et al.   BMJ-British Medical Journal

Case Report: Systemic Inflammatory Response and Fast Recovery in a Pediatric Patient With COVID-19

(2020) Adam Klocperk et al.   Frontiers in Immunology

The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

(2020) Camila Rosat Consiglio et al.   CELL

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

(2020) Naoki Kaneko et al.   CELL

Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

(2020) Conor N. Gruber et al.   CELL

Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2

(2020) Sandra C.A. Nielsen et al.   Cell Host & Microbe

Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS–CoV-2

(2020) Caroline Diorio et al.   JOURNAL OF CLINICAL INVESTIGATION

Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

(2020) Michael J. Carter et al.   NATURE MEDICINE

A dynamic COVID-19 immune signature includes associations with poor prognosis

(2020) Adam G. Laing et al.   NATURE MEDICINE

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

(2020) Mary Hongying Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptomic and clonal characterization of T cells in the human central nervous system

(2020) Jenna L. Pappalardo et al.   Science Immunology

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

(2020) Joana P. Bernardes et al.   IMMUNITY

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

Immune regulation by glucocorticoids can be linked to cell type–dependent transcriptional responses

(2019) Luis M. Franco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cells

(2019) Eleni P. Mimitou et al.   NATURE METHODS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Validation of a host response test to distinguish bacterial and viral respiratory infection

(2019) Emily C. Lydon et al.   EBioMedicine

Single-cell connectomic analysis of adult mammalian lungs

(2019) Micha Sam Brickman Raredon et al.   Science Advances

A Subset of Human Autoreactive CD1c-Restricted T Cells Preferentially Expresses TRBV4-1+TCRs

(2017) Tingxi Guo et al.   JOURNAL OF IMMUNOLOGY

Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data

(2017) Namita T. Gupta et al.   JOURNAL OF IMMUNOLOGY

Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

(2017) Deepak A. Rao et al.   NATURE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Long-Read Sequencing of Human Cytomegalovirus Transcriptome Reveals RNA Isoforms Carrying Distinct Coding Potentials

(2017) Zsolt Balázs et al.   Scientific Reports

HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins

(2016) Damien Bertheloot et al.   Cellular & Molecular Immunology

Leukocyte Trafficking to the Small Intestine and Colon

(2016) Aida Habtezion et al.   GASTROENTEROLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data: Table 1.

(2015) Namita T. Gupta et al.   BIOINFORMATICS

Immune Cell Activation by Enterotoxin Gene Cluster (egc)-Encoded and Non-egc Superantigens from Staphylococcus aureus

(2014) D. Grumann et al.   JOURNAL OF IMMUNOLOGY

Granzyme A Produces Bioactive IL-1β through a Nonapoptotic Inflammasome-Independent Pathway

(2014) Dagmar Hildebrand et al.   Cell Reports

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

IgBLAST: an immunoglobulin variable domain sequence analysis tool

(2013) Jian Ye et al.   NUCLEIC ACIDS RESEARCH

CXCL10 and autoimmune diseases

(2008) Eun Young Lee et al.   AUTOIMMUNITY REVIEWS