Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections
Authors
Keywords
-
Journal
IMMUNITY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-04-28
DOI
10.1016/j.immuni.2021.04.002
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial
- (2021) Viviane C Veiga et al. BMJ-British Medical Journal
- Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia
- (2021) Ivan O. Rosas et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Brescia, Italy
- (2020) Paola Toniati et al. AUTOIMMUNITY REVIEWS
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- (2020) Zhuo Zhou et al. Cell Host & Microbe
- Immunology of COVID-19: current state of the science
- (2020) Nicolas Vabret et al. IMMUNITY
- Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
- (2020) Safiya Richardson et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Severe Covid-19
- (2020) David A. Berlin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effective treatment of severe COVID-19 patients with tocilizumab
- (2020) Xiaoling Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the Alert for Cytokine Storm: Immunopathology in COVID ‐19
- (2020) Lauren A. Henderson et al. Arthritis & Rheumatology
- Longitudinal analyses reveal immunological misfiring in severe COVID-19
- (2020) Carolina Lucas et al. NATURE
- Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
- (2020) Jérôme Hadjadj et al. SCIENCE
- Type III interferons disrupt the lung epithelial barrier upon viral recognition
- (2020) Achille Broggi et al. SCIENCE
- The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection
- (2020) Ana Copaescu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma
- (2020) Hani Harb et al. NATURE IMMUNOLOGY
- SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
- (2020) Emma S. Winkler et al. NATURE IMMUNOLOGY
- An inflammatory cytokine signature predicts COVID-19 severity and survival
- (2020) Diane Marie Del Valle et al. NATURE MEDICINE
- In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
- (2020) Andrew W. Woodham et al. NATURE METHODS
- Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia
- (2020) Olivier Hermine et al. JAMA Internal Medicine
- Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia
- (2020) Carlo Salvarani et al. JAMA Internal Medicine
- Genetic mechanisms of critical illness in Covid-19
- (2020) Erola Pairo-Castineira et al. NATURE
- Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
- (2020) Carlos Salama et al. NEW ENGLAND JOURNAL OF MEDICINE
- Helios+ and Helios− Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires
- (2019) Angela M. Thornton et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Treatment of Severe Persistent Asthma with IL-6 Receptor blockade
- (2019) Brittany Esty et al. Journal of Allergy and Clinical Immunology-In Practice
- A Jagged 1–Notch 4 molecular switch mediates airway inflammation induced by ultrafine particles
- (2018) Mingcan Xia et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- CNS-targeted autoimmunity leads to increased influenza mortality in mice
- (2017) Justin D. Glenn et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo
- (2017) Mohit K. Verma et al. JOURNAL OF IMMUNOLOGICAL METHODS
- IL-6 ameliorates acute lung injury in influenza virus infection
- (2017) Mei-Lin Yang et al. Scientific Reports
- Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology
- (2017) Chloe J. Pyle et al. PLoS Pathogens
- β-catenin-mediated adhesion is required for successful preimplantation mouse embryo development
- (2016) Daniel Messerschmidt et al. DEVELOPMENT
- A Distinct Function of Regulatory T Cells in Tissue Protection
- (2015) Nicholas Arpaia et al. CELL
- Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair
- (2015) Dietmar M.W. Zaiss et al. IMMUNITY
- Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor–notch signaling cascade
- (2015) Mingcan Xia et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Control of peripheral tolerance by regulatory T cell–intrinsic Notch signaling
- (2015) Louis-Marie Charbonnier et al. NATURE IMMUNOLOGY
- Respiratory epithelial cells orchestrate pulmonary innate immunity
- (2015) Jeffrey A Whitsett et al. NATURE IMMUNOLOGY
- The alarmin IL-33 promotes regulatory T-cell function in the intestine
- (2014) Chris Schiering et al. NATURE
- A Special Population of Regulatory T Cells Potentiates Muscle Repair
- (2013) Dalia Burzyn et al. CELL
- Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor
- (2013) Dietmar M.W. Zaiss et al. IMMUNITY
- Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection
- (2013) A. M. Jamieson et al. SCIENCE
- Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development
- (2013) Antoine Reginensi et al. PLoS Genetics
- Enhanced Tim3 Activity Improves Survival after Influenza Infection
- (2012) J. L. Cho et al. JOURNAL OF IMMUNOLOGY
- Essential role of IL-6 in protection against H1N1 influenza virus by promoting neutrophil survival in the lung
- (2012) O Dienz et al. Mucosal Immunology
- Distinct Spatial and Molecular Features of Notch Pathway Assembly in Regulatory T Cells
- (2012) L. R. Perumalsamy et al. Science Signaling
- Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection
- (2011) Bruno Moltedo et al. PLoS Pathogens
- The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
- (2010) Nailing Zhang et al. DEVELOPMENTAL CELL
- Differences in Wound Healing in Mice with Deficiency of IL-6 versus IL-6 Receptor
- (2010) M. M. McFarland-Mancini et al. JOURNAL OF IMMUNOLOGY
- Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma
- (2009) Raffi Tachdjian et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
- (2008) Yuri P. Rubtsov et al. IMMUNITY
- Coordination of Early Protective Immunity to Viral Infection by Regulatory T Cells
- (2008) J. M. Lund et al. SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started