Polygenic Risk Scores Predict Hypertension Onset and Cardiovascular Risk

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers

(2020) Nina Mars et al.   NATURE MEDICINE

Association of Age of Onset of Hypertension With Cardiovascular Diseases and Mortality

(2020) Chi Wang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

Polygenic prediction via Bayesian regression and continuous shrinkage priors

(2019) Tian Ge et al.   Nature Communications

Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys

(2019) Bin Zhou et al.   LANCET

Early Onset Hypertension Is Associated With Hypertensive End-Organ Damage Already by MidLife

(2019) Karri Suvila et al.   HYPERTENSION

Brief Overview of a Decade of Genome-Wide Association Studies on Primary Hypertension

(2018) Afifah Binti Azam et al.   International Journal of Endocrinology

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

(2018) Evangelos Evangelou et al.   NATURE GENETICS

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cohort Profile: The National FINRISK Study

(2017) Katja Borodulin et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

(2017) Helen R Warren et al.   NATURE GENETICS

Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study

(2017) Teemu J Niiranen et al.   BMJ-British Medical Journal

Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study

(2017) Teemu J Niiranen et al.   BMJ-British Medical Journal

Genomic prediction of coronary heart disease

(2016) Gad Abraham et al.   EUROPEAN HEART JOURNAL

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

(2016) Thomas J Hoffmann et al.   NATURE GENETICS

Prediction of Blood Pressure and Blood Pressure Change With a Genetic Risk Score

(2015) Teemu J. Niiranen et al.   Journal of Clinical Hypertension

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015) Mohammad H Forouzanfar et al.   LANCET

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

The Role of Genetic Risk Score in Predicting the Risk of Hypertension in the Korean population: Korean Genome and Epidemiology Study

(2015) Nam-Kyoo Lim et al.   PLoS One

Comparing two correlated C indices with right-censored survival outcome: a one-shot nonparametric approach

(2014) Le Kang et al.   STATISTICS IN MEDICINE

A Risk Score for Predicting Near-Term Incidence of Hypertension: The Framingham Heart Study

(2013) Nisha I. Parikh et al.   ANNALS OF INTERNAL MEDICINE

Advances in Measuring the Effect of Individual Predictors of Cardiovascular Risk: The Role of Reclassification Measures

(2013) Nancy R. Cook et al.   ANNALS OF INTERNAL MEDICINE

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

A Blood Pressure Genetic Risk Score Is a Significant Predictor of Incident Cardiovascular Events in 32 669 Individuals

(2013) Aki S. Havulinna et al.   HYPERTENSION

Childhood Physical, Environmental, and Genetic Predictors of Adult Hypertension

(2012) Jonna Juhola et al.   CIRCULATION

Collinearity: a review of methods to deal with it and a simulation study evaluating their performance

(2012) Carsten F. Dormann et al.   ECOGRAPHY

Prediction of Blood Pressure Changes Over Time and Incidence of Hypertension by a Genetic Risk Score in Swedes

(2012) Cristiano Fava et al.   HYPERTENSION

PredictABEL: an R package for the assessment of risk prediction models

(2011) Suman Kundu et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Validating the Framingham Hypertension Risk Score

(2009) Mika Kivimäki et al.   HYPERTENSION

Genome-wide association study identifies eight loci associated with blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS