Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs–NF–κB signaling pathway and pyroptosis after secondary spinal cord injury

Excess administration of miR-340-5p ameliorates spinal cord injury-induced neuroinflammation and apoptosis by modulating the P38-MAPK signaling pathway

(2020) Zhanyang Qian et al.   BRAIN BEHAVIOR AND IMMUNITY

Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury

(2020) Zhongyuan Liu et al.   Journal of Neuroinflammation

Carbon monoxide releasing molecule-3 alleviates neuron death after spinal cord injury via inflammasome regulation

(2019) Gang Zheng et al.   EBioMedicine

Antidepressive effects of kaempferol mediated by reduction of oxidative stress, proinflammatory cytokines and up-regulation of AKT/β-catenin cascade

(2019) Wenqi Gao et al.   METABOLIC BRAIN DISEASE

Combinational Treatment of Bioscaffolds and Extracellular Vesicles in Spinal Cord Injury

(2019) Xizhi Wang et al.   Frontiers in Molecular Neuroscience

Kaempferol attenuates neuroinflammation and blood brain barrier dysfunction to improve neurological deficits in cerebral ischemia/reperfusion rats

(2019) Wei-Han Li et al.   BRAIN RESEARCH

Lion’s Mane Mushroom, Hericium erinaceus (Bull.: Fr.) Pers. Suppresses H2O2-Induced Oxidative Damage and LPS-Induced Inflammation in HT22 Hippocampal Neurons and BV2 Microglia

(2019) Kushairi et al.   Antioxidants

Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway

(2018) Xiao Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Microglial Inflammasome Activation in Penetrating Ballistic-Like Brain Injury

(2018) Stephanie W. Lee et al.   JOURNAL OF NEUROTRAUMA

Longitudinal electrophysiological changes after cervical hemi-contusion spinal cord injury in rats

(2018) Zucheng Huang et al.   NEUROSCIENCE LETTERS

PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

(2018) Justin Rustenhoven et al.   Molecular Neurodegeneration

Correction to: HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway

(2018) Shalini Swaroop et al.   Journal of Neuroinflammation

Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-κB Pathway

(2018) Jingyi Hou et al.   MOLECULES

Kaempferol protects mice from d-GalN/LPS-induced acute liver failure by regulating the ER stress-Grp78-CHOP signaling pathway

(2018) Huijuan Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

High-Mobility Group Box 1 (HMGB1) Is Elevated Systemically in Persons with Acute or Chronic Traumatic Spinal Cord Injury

(2017) Angelos Papatheodorou et al.   JOURNAL OF NEUROTRAUMA

Central Nervous System Injury and Nicotinamide Adenine Dinucleotide Phosphate Oxidase: Oxidative Stress and Therapeutic Targets

(2017) Ramona E. von Leden et al.   JOURNAL OF NEUROTRAUMA

Overview of Inflammation in Neurometabolic Diseases

(2017) Gregory A. Grabowski   Seminars in Pediatric Neurology

Low-level laser facilitates alternatively activated macrophage/microglia polarization and promotes functional recovery after crush spinal cord injury in rats

(2017) Ji Wei Song et al.   Scientific Reports

Post-translational regulation of inflammasomes

(2016) Jie Yang et al.   Cellular & Molecular Immunology

FK506 Attenuates the Inflammation in Rat Spinal Cord Injury by Inhibiting the Activation of NF-κB in Microglia Cells

(2016) Gang Liu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Downregulation of miR-199b promotes the acute spinal cord injury through IKKβ-NF-κB signaling pathway activating microglial cells

(2016) Heng-Jun Zhou et al.   EXPERIMENTAL CELL RESEARCH

Mechanical Design and Analysis of a Unilateral Cervical Spinal Cord Contusion Injury Model in Non-Human Primates

(2016) Carolyn J. Sparrey et al.   JOURNAL OF NEUROTRAUMA

Inflammogenesis of Secondary Spinal Cord Injury

(2016) M. Akhtar Anwar et al.   Frontiers in Cellular Neuroscience

Cellular and subcellular oxidative stress parameters following severe spinal cord injury

(2016) Nishant P. Visavadiya et al.   Redox Biology

Methionine Sulfoxide Reductase A Negatively Controls Microglia-Mediated Neuroinflammation via Inhibiting ROS/MAPKs/NF-κB Signaling Pathways Through a Catalytic Antioxidant Function

(2015) Hua Fan et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of Amaranthus on Advanced Glycation End-Products Induced Cytotoxicity and Proinflammatory Cytokine Gene Expression in SH-SY5Y Cells

(2015) Warisa Amornrit et al.   MOLECULES

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

Batroxobin protects against spinal cord injury in rats by promoting the expression of vascular endothelial growth factor to reduce apoptosis

(2015) HUI YU et al.   Experimental and Therapeutic Medicine

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

1-O-Tigloyl-1-O-deacetyl-nimbolinin B Inhibits LPS-Stimulated Inflammatory Responses by Suppressing NF-κB and JNK Activation in Microglia Cells

(2014) Li Tao et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Inflammasomes in the CNS

(2014) John G. Walsh et al.   NATURE REVIEWS NEUROSCIENCE

Curcumin abrogates LPS-induced pro-inflammatory cytokines in RAW 264.7 macrophages. Evidence for novel mechanisms involving SOCS-1, -3 and p38 MAPK

(2013) Morgana Rodrigues Guimarães et al.   ARCHIVES OF ORAL BIOLOGY

Multifaceted effects of rapamycin on functional recovery after spinal cord injury in rats through autophagy promotion, anti-inflammation, and neuroprotection

(2012) Hsien-Chih Chen et al.   JOURNAL OF SURGICAL RESEARCH

Regulation of inflammasome signaling

(2012) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

(2011) SE Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Oxidative stress in spinal cord injury and antioxidant-based intervention

(2011) Z Jia et al.   SPINAL CORD

Administration of Chondroitinase ABC Rostral or Caudal to a Spinal Cord Injury Site Promotes Anatomical but Not Functional Plasticity

(2009) Veronica J. Tom et al.   JOURNAL OF NEUROTRAUMA

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

THE SELECTIVE ADENOSINE A2A RECEPTOR AGONIST CGS 21680 REDUCES JNK MAPK ACTIVATION IN OLIGODENDROCYTES IN INJURED SPINAL CORD

(2009) Tiziana Genovese et al.   SHOCK