Oxidative stress induces downregulation of TP53INP2 and suppresses osteogenic differentiation of BMSCs during osteoporosis through the autophagy degradation pathway

Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells

(2020) Abdul Qadir et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Osteoporosis: From Molecular Mechanisms to Therapies

(2020) Chih-Hsin Tang   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

P53 and Parkin co-regulate mitophagy in bone marrow mesenchymal stem cells to promote the repair of early steroid-induced osteonecrosis of the femoral head

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Regulatory Role of RNA N6-Methyladenosine Modification in Bone Biology and Osteoporosis

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Bone Regeneration, Reconstruction and Use of Osteogenic Cells; from Basic Knowledge, Animal Models to Clinical Trials

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HNGF6A Inhibits Oxidative Stress-Induced MC3T3-E1 Cell Apoptosis and Osteoblast Phenotype Inhibition by Targeting Circ_0001843/miR-214 Pathway

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Let-7a-5p inhibits BMSCs osteogenesis in postmenopausal osteoporosis mice

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H19 and Foxc2 synergistically promotes osteogenic differentiation of BMSCs via Wnt-β-catenin pathway

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The Molecular Mechanism of Vitamin E as a Bone-Protecting Agent: A Review on Current Evidence

(2019) Sok Wong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction

(2019) Zhiyuan You et al.   Autophagy

Role of autophagy in the regulation of adipose tissue biology

(2019) Montserrat Romero et al.   CELL CYCLE

Regulation of death receptor signaling by the autophagy protein TP53INP2

(2019) Saška Ivanova et al.   EMBO JOURNAL

Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function

(2019) Fabio Penna et al.   JOURNAL OF MOLECULAR BIOLOGY

TP 53 INP 2 mediates autophagic degradation of ubiquitinated proteins through its ubiquitin‐interacting motif

(2019) Yinfeng Xu et al.   FEBS LETTERS

SUMOylation Evoked by Oxidative Stress Reduced Lens Epithelial Cell Antioxidant Functions by Increasing the Stability and Transcription of TP53INP1 in Age-Related Cataracts

(2019) Bo Lu et al.   Oxidative Medicine and Cellular Longevity

MiR‐291a‐3p regulates the BMSCs differentiation via targeting DKK1 in dexamethasone‐induced osteoporosis

(2019) Zhe‐Hai Li et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Cellular quality control by the ubiquitin-proteasome system and autophagy

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Coenzyme Q10 Regulation of Apoptosis and Oxidative Stress in H2O2 Induced BMSC Death by Modulating the Nrf-2/NQO-1 Signaling Pathway and Its Application in a Model of Spinal Cord Injury

(2019) Xing Li et al.   Oxidative Medicine and Cellular Longevity

Autophagy activation facilitates mechanical stimulation-promoted osteoblast differentiation and ameliorates hindlimb unloading-induced bone loss

(2018) Zezhu Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteasome inhibitor bortezomib is a novel therapeutic agent for focal radiation-induced osteoporosis

(2018) Abhishek Chandra et al.   FASEB JOURNAL

Melatonin alleviates oxidative stress-inhibited osteogenesis of human bone marrow-derived mesenchymal stem cells through AMPK activation

(2018) Sooho Lee et al.   International Journal of Medical Sciences

Overexpression of Sirt1 in Mesenchymal Stem Cells Protects against Bone Loss in Mice by FOXO3a Deacetylation and Oxidative Stress Inhibition

(2018) Wen Sun et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

TP53INP2 regulates adiposity by activating β-catenin through autophagy-dependent sequestration of GSK3β

(2018) Montserrat Romero et al.   NATURE CELL BIOLOGY

Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis

(2018) Huan Jing et al.   Cell Death & Disease

Role of Teriparatide in Glucocorticoid-induced Osteoporosis through Regulating Cellular Reactive Oxygen Species

(2018) Tao Wang et al.   Orthopaedic Surgery

Long noncoding RNA Bmncr regulates mesenchymal stem cell fate during skeletal aging

(2018) Chang-Jun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis

(2018) Yunshu Wu et al.   Nature Communications

Evidence of the Role of R-Spondin 1 and Its Receptor Lgr4 in the Transmission of Mechanical Stimuli to Biological Signals for Bone Formation

(2017) Gui-Xun Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway

(2016) Chao Zhu et al.   CELLULAR SIGNALLING

Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses

(2016) Qiaozhen Zhou et al.   DISEASE MARKERS

Is TP53INP2 a critical regulator of muscle mass?

(2015) David Sala et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Oxidative damage to osteoblasts can be alleviated by early autophagy through the endoplasmic reticulum stress pathway—Implications for the treatment of osteoporosis

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Estimating prevalence of osteoporosis: examples from industrialized countries

(2014) S. W. Wade et al.   Archives of Osteoporosis

Chaperones, but not oxidized proteins, are ubiquitinated after oxidative stress

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Spinal cord injury causes bone loss through peroxisome proliferator-activated receptor-γ and Wnt signalling

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Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation

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Differential responsiveness to 17β-estradiol of mesenchymal stem cells from postmenopausal women between osteoporosis and osteoarthritis

(2011) W.-J. Jin et al.   OSTEOPOROSIS INTERNATIONAL

Association of Oxidative Stress with Postmenopausal Osteoporosis and the Effects of Hydrogen Peroxide on Osteoclast Formation in Human Bone Marrow Cell Cultures

(2010) Ki Hyun Baek et al.   CALCIFIED TISSUE INTERNATIONAL

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Oxidative Stress Stimulates Apoptosis and Activates NF-κB in Osteoblastic Cells via a PKCβ/p66shcSignaling Cascade: Counter Regulation by Estrogens or Androgens

(2010) Maria Almeida et al.   MOLECULAR ENDOCRINOLOGY

The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells

(2009) Caroline Mauvezin et al.   EMBO REPORTS

The TP53INP2 Protein Is Required for Autophagy in Mammalian Cells

(2008) Jonathan Nowak et al.   MOLECULAR BIOLOGY OF THE CELL