Noninvasive preimplantation genetic testing for aneuploidy exhibits high rates of deoxyribonucleic acid amplification failure and poor correlation with results obtained using trophectoderm biopsy

Multicenter prospective study of concordance between embryo cell-free DNA and trophectoderm biopsies from 1,301 human blastocysts

(2020) Carmen Rubio et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Preimplantation genetic testing for aneuploidy in poor ovarian responders with four or fewer oocytes retrieved

(2020) Jie Deng et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Minimally invasive preimplantation genetic testing using blastocyst culture medium

(2019) Jiao Jiao et al.   HUMAN REPRODUCTION

Noninvasive preimplantation genetic testing for aneuploidy in spent medium may be more reliable than trophectoderm biopsy

(2019) Lei Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial

(2019) Santiago Munné et al.   FERTILITY AND STERILITY

Pushing the limits of detection: investigation of cell-free DNA for aneuploidy screening in embryos

(2018) Jacqueline R. Ho et al.   FERTILITY AND STERILITY

Origin and composition of cell-free DNA in spent medium from human embryo culture during preimplantation development

(2018) M Vera-Rodriguez et al.   HUMAN REPRODUCTION

Evaluation of a novel non-invasive preimplantation genetic screening approach

(2018) Valeriy Kuznyetsov et al.   PLoS One

DNA methylation-based age prediction and telomere length in white blood cells and cumulus cells of infertile women with normal or poor response to ovarian stimulation

(2018) Scott J. Morin et al.   Aging-US

Preimplantation genetic testing for aneuploidy is cost-effective, shortens treatment time, and reduces the risk of failed embryo transfer and clinical miscarriage

(2018) Shelby A. Neal et al.   FERTILITY AND STERILITY

Ability to detect aneuploidy from cell free DNA collected from media is dependent on the stage of development of the embryo

(2017) M. Lane et al.   FERTILITY AND STERILITY

Characterizing nuclear and mitochondrial DNA in spent embryo culture media: genetic contamination identified

(2017) Elizabeth R. Hammond et al.   FERTILITY AND STERILITY

Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization

(2016) Juanjuan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Next-generation sequencing: the dawn of a new era for preimplantation genetic diagnostics

(2014) Dagan Wells   FERTILITY AND STERILITY

Application of next-generation sequencing technology for comprehensive aneuploidy screening of blastocysts in clinical preimplantation genetic screening cycles

(2014) Francesco Fiorentino et al.   HUMAN REPRODUCTION

Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial

(2013) Richard T. Scott et al.   FERTILITY AND STERILITY

Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

(2012) C. Zong et al.   SCIENCE