Noninvasive preimplantation genetic testing for aneuploidy in spent medium may be more reliable than trophectoderm biopsy

Chromosome screening using culture medium of embryos fertilised in vitro: a pilot clinical study

(2019) Rui Fang et al.   Journal of Translational Medicine

Pregnancy outcomes from more than 1,800 in vitro fertilization cycles with the use of 24-chromosome single-nucleotide polymorphism–based preimplantation genetic testing for aneuploidy

(2018) Alexander L. Simon et al.   FERTILITY AND STERILITY

Pushing the limits of detection: investigation of cell-free DNA for aneuploidy screening in embryos

(2018) Jacqueline R. Ho et al.   FERTILITY AND STERILITY

Origin and composition of cell-free DNA in spent medium from human embryo culture during preimplantation development

(2018) M Vera-Rodriguez et al.   HUMAN REPRODUCTION

Evaluation of a novel non-invasive preimplantation genetic screening approach

(2018) Valeriy Kuznyetsov et al.   PLoS One

Inconclusive chromosomal assessment after blastocyst biopsy: prevalence, causative factors and outcomes after re-biopsy and re-vitrification. A multicenter experience

(2018) Danilo Cimadomo et al.   HUMAN REPRODUCTION

Rates of live birth after mosaic embryo transfer compared with euploid embryo transfer

(2018) Lei Zhang et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Three-dimensional genome structures of single diploid human cells

(2018) Longzhi Tan et al.   SCIENCE

Transfer of embryos with segmental mosaicism is associated with a significant reduction in live-birth rate

(2018) Temeka Zore et al.   FERTILITY AND STERILITY

Deoxyribonucleic acid detection in blastocoelic fluid: a new predictor of embryo ploidy and viable pregnancy

(2018) M. Cristina Magli et al.   FERTILITY AND STERILITY

Global multicenter randomized controlled trial comparing single embryo transfer with embryo selected by preimplantation genetic screening using next-generation sequencing versus morphologic assessment

(2017) S. Munne et al.   FERTILITY AND STERILITY

Preimplantation genetic screening: what is the clinical efficiency?

(2017) Richard J. Paulson   FERTILITY AND STERILITY

Analysis of implantation and ongoing pregnancy rates following the transfer of mosaic diploid–aneuploid blastocysts

(2017) Elpida Fragouli et al.   HUMAN GENETICS

Single-cell DNA methylome sequencing of human preimplantation embryos

(2017) Ping Zhu et al.   NATURE GENETICS

Non-invasive preimplantation genetic screening using array comparative genomic hybridization on spent culture media: a proof-of-concept pilot study

(2017) Michael Feichtinger et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)

(2017) Chongyi Chen et al.   SCIENCE

Why do euploid embryos miscarry? A case-control study comparing the rate of aneuploidy within presumed euploid embryos that resulted in miscarriage or live birth using next-generation sequencing

(2016) Susan M. Maxwell et al.   FERTILITY AND STERILITY

Proof of concept: preimplantation genetic screening without embryo biopsy through analysis of cell-free DNA in spent embryo culture media

(2016) Mousa I. Shamonki et al.   FERTILITY AND STERILITY

Preimplantation genetic testing: polar bodies, blastomeres, trophectoderm cells, or blastocoelic fluid?

(2016) M. Cristina Magli et al.   FERTILITY AND STERILITY

Preimplantation genetic screening: who benefits?

(2016) Hey-Joo Kang et al.   FERTILITY AND STERILITY

Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization

(2016) Juanjuan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential

(2016) Helen Bolton et al.   Nature Communications

Single-Cell Whole-Genome Amplification and Sequencing: Methodology and Applications

(2015) Lei Huang et al.   Annual Review of Genomics and Human Genetics

Blastocoel fluid from differentiated blastocysts harbors embryonic genomic material capable of a whole-genome deoxyribonucleic acid amplification and comprehensive chromosome microarray analysis

(2015) Kyle J. Tobler et al.   FERTILITY AND STERILITY

In vitro fertilization with preimplantation genetic screening improves implantation and live birth in women age 40 through 43

(2015) Hsiao-Ling Lee et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Healthy Babies after Intrauterine Transfer of Mosaic Aneuploid Blastocysts

(2015) Ermanno Greco et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development and validation of a next-generation sequencing–based protocol for 24-chromosome aneuploidy screening of embryos

(2014) Francesco Fiorentino et al.   FERTILITY AND STERILITY

Correlation between standard blastocyst morphology, euploidy and implantation: an observational study in two centers involving 956 screened blastocysts

(2014) Antonio Capalbo et al.   HUMAN REPRODUCTION

The origin, mechanisms, incidence and clinical consequences of chromosomal mosaicism in humans

(2014) Tyl H. Taylor et al.   HUMAN REPRODUCTION UPDATE

Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation

(2014) Dagan Wells et al.   JOURNAL OF MEDICAL GENETICS

Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial

(2013) Richard T. Scott et al.   FERTILITY AND STERILITY

The nature of aneuploidy with increasing age of the female partner: a review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening

(2013) Jason M. Franasiak et al.   FERTILITY AND STERILITY

Single embryo transfer with comprehensive chromosome screening results in improved ongoing pregnancy rates and decreased miscarriage rates

(2012) E. J. Forman et al.   HUMAN REPRODUCTION

Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell

(2012) C. Zong et al.   SCIENCE

Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation

(2010) E. Fragouli et al.   HUMAN REPRODUCTION

SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts

(2010) L. E. Northrop et al.   MOLECULAR HUMAN REPRODUCTION

Comprehensive analysis of karyotypic mosaicism between trophectoderm and inner cell mass

(2010) D.S. Johnson et al.   MOLECULAR HUMAN REPRODUCTION

Circulating Nucleic Acids in Plasma and Serum

(2009) Peter B. Gahan et al.   Annals of the New York Academy of Sciences