Origin and composition of cell-free DNA in spent medium from human embryo culture during preimplantation development

Ability to detect aneuploidy from cell free DNA collected from media is dependent on the stage of development of the embryo

(2017) M. Lane et al.   FERTILITY AND STERILITY

Assessing the true incidence of mosaicism in preimplantation embryos

(2017) Maria Vera-Rodriguez et al.   FERTILITY AND STERILITY

Characterizing nuclear and mitochondrial DNA in spent embryo culture media: genetic contamination identified

(2017) Elizabeth R. Hammond et al.   FERTILITY AND STERILITY

Non-invasive preimplantation genetic screening using array comparative genomic hybridization on spent culture media: a proof-of-concept pilot study

(2017) Michael Feichtinger et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Proof of concept: preimplantation genetic screening without embryo biopsy through analysis of cell-free DNA in spent embryo culture media

(2016) Mousa I. Shamonki et al.   FERTILITY AND STERILITY

Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization

(2016) Juanjuan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends

(2016) K. C. Allen Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular analysis of products of conception obtained by hysteroembryoscopy from infertile couples

(2015) Inmaculada Campos-Galindo et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis

(2015) Maria Vera-Rodriguez et al.   Nature Communications

Development and validation of a next-generation sequencing–based protocol for 24-chromosome aneuploidy screening of embryos

(2014) Francesco Fiorentino et al.   FERTILITY AND STERILITY

New Tools for Embryo Selection: Comprehensive Chromosome Screening by Array Comparative Genomic Hybridization

(2014) Lorena Rodrigo et al.   Biomed Research International

A Single Cell Level Based Method for Copy Number Variation Analysis by Low Coverage Massively Parallel Sequencing

(2013) Chunlei Zhang et al.   PLoS One

Outcomes of vitrified early cleavage-stage and blastocyst-stage embryos in a cryopreservation program: evaluation of 3,150 warming cycles

(2012) Ana Cobo et al.   FERTILITY AND STERILITY

Validation of array comparative genome hybridization for diagnosis of translocations in preimplantation human embryos

(2012) Pere Colls et al.   REPRODUCTIVE BIOMEDICINE ONLINE

The relationship between blastocyst morphology, chromosomal abnormality, and embryo gender

(2010) Samer Alfarawati et al.   FERTILITY AND STERILITY

Improving FISH diagnosis for preimplantation genetic aneuploidy screening

(2010) P. Mir et al.   HUMAN REPRODUCTION

SNP microarray-based 24 chromosome aneuploidy screening is significantly more consistent than FISH

(2010) N. R. Treff et al.   MOLECULAR HUMAN REPRODUCTION