An improved in vitro model for studying the structural and functional properties of the endothelial glycocalyx in arteries, capillaries and veins

Endothelial barrier function is differentially regulated by CEACAM1-mediated signaling

(2018) Sharang Ghavampour et al.   FASEB JOURNAL

Oncotically Driven Control over Glycocalyx Dimension for Cell Surface Engineering and Protein Binding in the Longitudinal Direction

(2018) Erika M. J. Siren et al.   Scientific Reports

Experimental cerebral malaria is associated with profound loss of both glycan and protein components of the endothelial glycocalyx

(2018) Casper Hempel et al.   FASEB JOURNAL

“Sweet” Architecture-Dependent Uptake of Glycocalyx-Mimicking Nanoparticles Based on Biodegradable Aliphatic Polyesters by Macrophages

(2017) Libin Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of inflammation induced shedding of the endothelial glycocalyx with low molecular weight heparin

(2017) Herbert H. Lipowsky et al.   MICROVASCULAR RESEARCH

The glycocalyx regulates the uptake of nanoparticles by human endothelial cells in vitro

(2017) Leonhard Möckl et al.   Nanomedicine

Microvasculature on a chip: study of the Endothelial Surface Layer and the flow structure of Red Blood Cells

(2017) Daria Tsvirkun et al.   Scientific Reports

Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis

(2016) Shibin Feng et al.   BIOMATERIALS

Flow-induced stress on adherent cells in microfluidic devices

(2015) Jonathan Shemesh et al.   LAB ON A CHIP

Creating perfused functional vascular channels using 3D bio-printing technology

(2014) Vivian K. Lee et al.   BIOMATERIALS

Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction

(2014) Raina Ramnath et al.   FASEB JOURNAL

Loss of Syndecan-1 Induces a Pro-inflammatory Phenotype in Endothelial Cells with a Dysregulated Response to Atheroprotective Flow

(2014) Peter L. Voyvodic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ICAM-1 signaling in endothelial cells

(2014) Charlotte Lawson et al.   Pharmacological Reports

The Adaptive Remodeling of Endothelial Glycocalyx in Response to Fluid Shear Stress

(2014) Ye Zeng et al.   PLoS One

Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease

(2014) Hasan Erbil Abaci et al.   Scientific Reports

A standalone perfusion platform for drug testing and target validation in micro-vessel networks

(2013) Boyang Zhang et al.   Biomicrofluidics

Shear stress activates extracellular signal-regulated kinase 1/2 via the angiotensin II type 1 receptor

(2013) Bhama Ramkhelawon et al.   FASEB JOURNAL

Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application

(2013) K. Pollinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechano-sensing and transduction by endothelial surface glycocalyx: composition, structure, and function

(2013) Bingmei M. Fu et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Acute and Chronic Shear Stress Differently Regulate Endothelial Internalization of Nanocarriers Targeted to Platelet-Endothelial Cell Adhesion Molecule-1

(2012) Jingyan Han et al.   ACS Nano

Hemodynamic shear stress characteristic of atherosclerosis-resistant regions promotes glycocalyx formation in cultured endothelial cells

(2012) Andrew Koo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Spatio-temporal development of the endothelial glycocalyx layer and its mechanical property in vitro

(2012) K. Bai et al.   Journal of the Royal Society Interface

A multi-shear perfusion bioreactor for investigating shear stress effects in endothelial cell constructs

(2012) Menahem Y. Rotenberg et al.   LAB ON A CHIP

Quantification of the endothelial surface glycocalyx on rat and mouse blood vessels

(2012) Wan-Yi Yen et al.   MICROVASCULAR RESEARCH

Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure

(2012) Sason Torosean et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Should clot composition affect choice of endovascular therapy?

(2012) B. P. Mehta et al.   NEUROLOGY

Imaging the Endothelial Glycocalyx In Vitro by Rapid Freezing/Freeze Substitution Transmission Electron Microscopy

(2011) Eno E. Ebong et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Shear stress increases endothelial hyaluronan synthase 2 and hyaluronan synthesis especially in regard to an atheroprotective flow profile

(2011) Julian Maroski et al.   EXPERIMENTAL PHYSIOLOGY

Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1

(2011) Tridib Bhowmick et al.   JOURNAL OF CONTROLLED RELEASE

Concentration and Time Effects of Dextran Exposure on Endothelial Cell Viability, Attachment, and Inflammatory Marker Expression In Vitro

(2010) Leonie Rouleau et al.   ANNALS OF BIOMEDICAL ENGINEERING

Therapeutic strategies targeting the endothelial glycocalyx: acute deficits, but great potential

(2010) B. F. Becker et al.   CARDIOVASCULAR RESEARCH

Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium

(2010) Dimana O. Miteva et al.   CIRCULATION RESEARCH

Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS

(2010) Veronika Makó et al.   CYTOMETRY PART A

PECAM-targeted delivery of SOD inhibits endothelial inflammatory response

(2010) Vladimir V. Shuvaev et al.   FASEB JOURNAL

The Recovery Time Course of the Endothelial Cell Glycocalyx In Vivo and Its Implications In Vitro

(2009) Daniel R. Potter et al.   CIRCULATION RESEARCH

The Glycocalyx of the Human Umbilical Vein Endothelial Cell

(2009) Daniel Chappell et al.   CIRCULATION RESEARCH

Role of glycocalyx in flow-induced production of nitric oxide and reactive oxygen species

(2009) Robert Kumagai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Determinants of Leukocyte Margination in Rectangular Microchannels

(2009) Abhishek Jain et al.   PLoS One

Arterial versus venous endothelial cells

(2008) Nathaniel G. dela Paz et al.   CELL AND TISSUE RESEARCH

The Hydrodynamically Relevant Endothelial Cell Glycocalyx Observed In Vivo Is Absent In Vitro

(2008) Daniel R. Potter et al.   CIRCULATION RESEARCH

Hypothesis: arterial glycocalyx dysfunction is the first step in the atherothrombotic process

(2008) M.I.M. Noble et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE