Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction

Glycosaminoglycan Regulation by VEGFA and VEGFC of the Glomerular Microvascular Endothelial Cell Glycocalyx in Vitro

(2013) Rebecca R. Foster et al.   AMERICAN JOURNAL OF PATHOLOGY

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart

(2013) Mari E. Strand et al.   FEBS Journal

The role of the glomerular endothelium in albumin handling

(2013) Simon Satchell   Nature Reviews Nephrology

Reactive Oxygen Species Modulate the Barrier Function of the Human Glomerular Endothelial Glycocalyx

(2013) Anurag Singh et al.   PLoS One

Th1 cytokine-induced syndecan-4 shedding by airway smooth muscle cells is dependent on mitogen-activated protein kinases

(2012) Xiahui Tan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Heparan Sulfate Chains of Syndecan-1 Regulate Ectodomain Shedding

(2012) Vishnu C. Ramani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition

(2012) Valentina Masola et al.   Journal of Translational Medicine

The glomerular endothelium emerges as a key player in diabetic nephropathy

(2012) Simon C. Satchell   KIDNEY INTERNATIONAL

Structural damage in diabetic nephropathy is associated with TNF-α system activity

(2011) José Manuel Fernández-Real et al.   ACTA DIABETOLOGICA

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

(2011) N. Gil et al.   DIABETES

Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability

(2011) Andrew HJ Salmon et al.   JOURNAL OF PATHOLOGY

Transmembrane Signaling Proteoglycans

(2010) John R. Couchman   Annual Review of Cell and Developmental Biology

Microvascular fluid exchange and the revised Starling principle

(2010) J. Rodney Levick et al.   CARDIOVASCULAR RESEARCH

Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus

(2010) L. N. Broekhuizen et al.   DIABETOLOGIA

Proteoglycans in health and disease: the multiple roles of syndecan shedding

(2010) Tina Manon-Jensen et al.   FEBS Journal

Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices

(2010) Shoujun Chen et al.   KIDNEY INTERNATIONAL

In VivoVisualization of Glomerular Microcirculation and Hyperfiltration in Streptozotocin-Induced Diabetic Rats

(2010) MINORU SATOH et al.   MICROCIRCULATION

Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion

(2009) D. Chappell et al.   CARDIOVASCULAR RESEARCH

Tumor necrosis factor-α as a therapeutic target for diabetic nephropathy

(2009) Juan F. Navarro-González et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A Disintegrin and Metalloproteinase 17 (ADAM17) Mediates Inflammation-induced Shedding of Syndecan-1 and -4 by Lung Epithelial Cells

(2009) Jessica Pruessmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syndecans Shed Their Reputation as Inert Molecules

(2009) M. D. Bass et al.   Science Signaling

TNF-α induced shedding of the endothelial glycocalyx is prevented by hydrocortisone and antithrombin

(2008) Daniel Chappell et al.   BASIC RESEARCH IN CARDIOLOGY

What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium?

(2008) S. C. Satchell et al.   DIABETOLOGIA

The Role of Inflammatory Cytokines in Diabetic Nephropathy

(2008) J. F. Navarro-Gonzalez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Properties of the Glomerular Barrier and Mechanisms of Proteinuria

(2008) Börje Haraldsson et al.   PHYSIOLOGICAL REVIEWS