Indole-3-carbinol ameliorates necroptosis and inflammation of intestinal epithelial cells in mice with ulcerative colitis by activating Aryl Hydrocarbon Receptor

Tumor Necrosis Factor Receptors: Pleiotropic Signaling Complexes and Their Differential Effects

(2020) Portia Gough et al.   Frontiers in Immunology

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

A pan-RAF inhibitor LY3009120 inhibits necroptosis by preventing phosphorylation of RIPK1 and alleviates dextran sulfate sodium-induced colitis

(2019) Chong Zhang et al.   CLINICAL SCIENCE

Environmental Risk Factors for Inflammatory Bowel Diseases: an Umbrella Review of Meta-analyses

(2019) Daniele Piovani et al.   GASTROENTEROLOGY

Activation of aryl hydrocarbon receptor regulates the LPS/IFNγ-induced inflammatory response by inducing ubiquitin-proteosomal and lysosomal degradation of RelA/p65

(2018) O. Domínguez-Acosta et al.   BIOCHEMICAL PHARMACOLOGY

A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival

(2018) Michael G. Kattah et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aryl hydrocarbon receptor and intestinal immunity

(2018) Bruno Lamas et al.   Mucosal Immunology

Modulation of CYP1A1 metabolism: From adverse health effects to chemoprevention and therapeutic options

(2018) Melina Mescher et al.   PHARMACOLOGY & THERAPEUTICS

The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

(2018) Amina Metidji et al.   IMMUNITY

The Role of the Aryl Hydrocarbon Receptor (AHR) in Immune and Inflammatory Diseases

(2018) Drew Neavin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Origin, Differentiation, and Function of Intestinal Macrophages

(2018) Calum C. Bain et al.   Frontiers in Immunology

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

(2017) Yu Matsuzawa-Ishimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chemically induced mouse models of acute and chronic intestinal inflammation

(2017) Stefan Wirtz et al.   Nature Protocols

Programmed Necrosis in the Cross Talk of Cell Death and Inflammation

(2015) Francis Ka-Ming Chan et al.   Annual Review of Immunology

The aryl hydrocarbon receptor/microRNA-212/132 axis in T cells regulates IL-10 production to maintain intestinal homeostasis

(2015) Ichino Chinen et al.   INTERNATIONAL IMMUNOLOGY

Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease

(2015) Ryuichi Okamoto et al.   JOURNAL OF GASTROENTEROLOGY

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Biologic agents for IBD: practical insights

(2015) Silvio Danese et al.   Nature Reviews Gastroenterology & Hepatology

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

(2014) Brigitta Stockinger et al.   Annual Review of Immunology

The Burden of Inflammatory Bowel Disease

(2014) Jennifer Devlen et al.   INFLAMMATORY BOWEL DISEASES

Integrin-linked Kinase Modulates Lipopolysaccharide- andHelicobacter pylori-induced Nuclear Factor κB-activated Tumor Necrosis Factor-α Production via Regulation of p65 Serine 536 Phosphorylation

(2014) Afsar U. Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3

(2014) Huayi Wang et al.   MOLECULAR CELL

The Ah Receptor Recruits IKKα to Its Target Binding Motifs to Phosphorylate Serine-10 in Histone H3 Required for Transcriptional Activation

(2014) Hisaka Kurita et al.   TOXICOLOGICAL SCIENCES

Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy

(2014) T Grabinger et al.   Cell Death & Disease

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Linear ubiquitination: a newly discovered regulator of cell signalling

(2013) Eva Rieser et al.   TRENDS IN BIOCHEMICAL SCIENCES

Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium

(2012) Claudia Günther et al.   GUT

You AhR What You Eat: Linking Diet and Immunity

(2011) Lora V. Hooper   CELL

IAPs: Guardians of RIPK1

(2011) M Darding et al.   CELL DEATH AND DIFFERENTIATION

Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

(2011) Ivan Monteleone et al.   GASTROENTEROLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL